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Showing 1–24 of 31 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Verbal Apraxia Clear all
Recruiting Phase 4 Interventional

Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech

NCT01818661
View directory record Official record
Conditions
PPA, Non-fluent Aphasia, Apraxia of Speech, Primary Progressive Non-fluent Aphasia, Primary Progressive Aphasia
Interventions
AV-1451
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Sep 7, 2026, 6:50 PM EDT
Completed Not applicable Interventional Results available

Treatment Intensity - Apraxia of Speech

NCT02332915
View directory record Official record
Conditions
Aphasia, CVA, Apraxia of Speech
Interventions
Sound Production Treatment (SPT)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 90 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 11, 2022 · Synced Sep 7, 2026, 6:50 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Central Mechanisms in Speech Motor Control Studied With H215O PET

NCT00001308
View directory record Official record
Conditions
Communication Disorder, Healthy, Stuttering, Tourette Syndrome, Voice Disorder
Interventions
Not listed
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
18 Years to 85 Years
Enrollment
1,163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1992 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Sep 7, 2026, 6:50 PM EDT
Completed Not applicable Interventional Results available

A Novel Treatment for Aphasia and Apraxia of Speech : Measurement of Outcomes

NCT01979159
View directory record Official record
Conditions
Apraxia of Speech, Aphasia
Interventions
Combined Aphasia and Apraxia of Speech Treatment (CAAST)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 75 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 18, 2019 · Synced Sep 7, 2026, 6:50 PM EDT
Completed Phase 1 Interventional

PiB PET Scanning in Speech and Language Based Dementias

NCT01623284
View directory record Official record
Conditions
PPA, Primary Progressive Aphasia, Aphasia, Non-fluent Aphasia, Semantic Dementia, Apraxia of Speech, Primary Progressive Nonfluent Aphasia, Progressive Aphasia
Interventions
C-11 PiB, F-18 FDG
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 21, 2015 · Synced Sep 7, 2026, 6:50 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

ReadMap: Reading in Stroke Alexia and Typical Aging

NCT06700005
View directory record Official record
Conditions
Aphasia, Stroke, Alexia
Interventions
Not listed
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 20, 2024 · Synced Sep 7, 2026, 6:50 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effects of tDCS on Apraxia of Speech in Non-Fluent Primary Progressive Aphasia

NCT04486586
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
Active tDCS plus Speech-Language Therapy, Sham plus Speech-Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 90 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Sep 7, 2026, 6:50 PM EDT
Active, not recruiting Not applicable Interventional

Treating Primary Progressive Aphasia and Apraxia of Speech Using Non-invasive Brain Stimulation

NCT05368350
View directory record Official record
Conditions
Primary Progressive Aphasia, Apraxia of Speech
Interventions
high-definition transcranial direct current stimulation (HD-tDCS)
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 85 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 7, 2026, 6:50 PM EDT
Active, not recruiting Not applicable Interventional

A Randomized Control Trial of Motor-based Intervention for CAS

NCT04642053
View directory record Official record
Conditions
Childhood Apraxia of Speech
Interventions
Dynamic Temporal and Tactile Cuing
Behavioral
Lead sponsor
New York University
Other
Eligibility
29 Months to 95 Months
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Sep 7, 2026, 6:50 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

ASSIST: Treatment for Childhood Apraxia of Speech

NCT03903120
View directory record Official record
Conditions
Childhood Apraxia of Speech
Interventions
ASSIST
Behavioral
Lead sponsor
Temple University
Other
Eligibility
4 Years to 9 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 7, 2026, 6:50 PM EDT
Not listed Not applicable Interventional

Motor Imagery for Treatment Enhancement and Efficacy in Persons With Apraxia of Speech

NCT06467136
View directory record Official record
Conditions
Apraxia, Oral, Apraxia of Speech
Interventions
Sound production treatment, Motor Imagery Practice
Behavioral
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Sep 7, 2026, 6:50 PM EDT
Recruiting Not applicable Interventional

Using tDCS in Speech-based Stroke Rehabilitation

NCT03452202
View directory record Official record
Conditions
Apraxia of Speech
Interventions
Soterix 1x1 line tDCS low-intensity stimulator, Sham
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 99 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
2
States / cities
New York, New York • White Plains, New York
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 7, 2026, 6:50 PM EDT
Terminated Not applicable Interventional Results available

Transcranial Magnetic Stimulation (TMS) for Primary Progressive Apraxia of Speech (PPAOS)

NCT03028324
View directory record Official record
Conditions
Apraxia Speech
Interventions
Transcranial Magnetic Stimulation (TMS)
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 25, 2020 · Synced Sep 7, 2026, 6:50 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Brain-based Understanding of Individual Language Differences After Stroke

NCT04991519
View directory record Official record
Conditions
Aphasia, Stroke, Alexia
Interventions
Not listed
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Sep 7, 2026, 6:50 PM EDT
Completed Not applicable Interventional Results available

Treatments of Acquired Apraxia of Speech

NCT01483807
View directory record Official record
Conditions
Aphasia, Apraxia of Speech, Stroke
Interventions
Sound Production Treatment - Blocked, Sound Production Treatment - Random
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 21, 2019 · Synced Sep 7, 2026, 6:50 PM EDT
Not yet recruiting Phase 2 Interventional

Role of Omega-DEK in Childhood Apraxia of Speech

NCT07216001
View directory record Official record
Conditions
Childhood Apraxia of Speech, Verbal Apraxia, Autism
Interventions
Omega-DEK, L-carnitine, Placebo
Drug
Lead sponsor
Claudia R. Morris
Other
Eligibility
36 Months to 6 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 7, 2026, 6:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Investigating the Effects of Rhythm and Entrainment on Fluency in People With Aphasia

NCT05248295
View directory record Official record
Conditions
Aphasia, Apraxia of Speech
Interventions
Unison speech (vs. solo), Metrical timing (vs. conversational)
Behavioral
Lead sponsor
MGH Institute of Health Professions
Other
Eligibility
18 Years to 80 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 17, 2025 · Synced Sep 7, 2026, 6:50 PM EDT
Active, not recruiting Not applicable Interventional

The Effects of Caregiver Training on DTTC Treatment Outcomes in CAS

NCT05916222
View directory record Official record
Conditions
Childhood Apraxia of Speech
Interventions
Dynamic Temporal and Tactile Cueing (DTTC)
Behavioral
Lead sponsor
New York University
Other
Eligibility
24 Months to 95 Months
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Hempstead, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Sep 7, 2026, 6:50 PM EDT
Completed Not applicable Interventional Results available

Apraxia of Speech: Comparison of EPG Treatment (Tx) and Sound Production Treatment (SPT)

NCT02554513
View directory record Official record
Conditions
Apraxia of Speech, Aphasia, Acquired, Speech Disorders
Interventions
EPG Tx, SPT
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 3, 2021 · Synced Sep 7, 2026, 6:50 PM EDT
Active, not recruiting Not applicable Interventional

Dose Frequency RCT on DTTC in Children With CAS

NCT05675306
View directory record Official record
Conditions
Childhood Apraxia of Speech
Interventions
Dynamic Temporal and Tactile Cueing Treatment
Behavioral
Lead sponsor
Marquette University
Other
Eligibility
30 Months to 95 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 20, 2025 · Synced Sep 7, 2026, 6:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Video Assisted Speech Technology to Enhance Motor Planning for Speech

NCT04764539
View directory record Official record
Conditions
Autism Spectrum Disorder, Apraxia of Speech
Interventions
Video Assisted Speech Therapy (VAST)
Behavioral
Lead sponsor
iTherapy, LLC
Other
Eligibility
4 Years to 8 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Vallejo, California
Source: ClinicalTrials.gov public record
Updated May 8, 2023 · Synced Sep 7, 2026, 6:50 PM EDT
Recruiting Not applicable Interventional

Measuring Aided Language Development

NCT06512168
View directory record Official record
Conditions
Down Syndrome, Cerebral Palsy, Apraxia of Speech, Speech Sound Disorder, Speech Disorders in Children, Speech and Language Disorder
Interventions
AAC Generative Language Intervention
Behavioral
Lead sponsor
University of Central Florida
Other
Eligibility
42 Months to 60 Months
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced Sep 7, 2026, 6:50 PM EDT
Not listed Early Phase 1 Interventional

Efficacy of START (Startle Rehabilitation Therapy) in the Treatment Stroke-induced Aphasia/Apraxia

NCT04816799
View directory record Official record
Conditions
Stroke, Aphasia, Apraxia of Speech
Interventions
Startle Adjuvant Rehabilitation Therapy (START)
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 100 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 21, 2022 · Synced Sep 7, 2026, 6:50 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Auditory Masking Effects on Speech Fluency in Aphasia and Apraxia of Speech

NCT02094014
View directory record Official record
Conditions
Apraxia of Speech, Aphasia, Cerebrovascular Accident
Interventions
Normal Auditory Feedback, Masked Auditory Feedback, Altered Auditory Feedback
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 11, 2016 · Synced Sep 7, 2026, 6:50 PM EDT