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Showing 1–24 of 31 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed No phase listed Observational Accepts healthy volunteers

Auditory Masking Effects on Speech Fluency in Aphasia and Apraxia of Speech

NCT02094014
Conditions
Apraxia of Speech, Aphasia, Cerebrovascular Accident
Interventions
Normal Auditory Feedback, Masked Auditory Feedback, Altered Auditory Feedback
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Not applicable Interventional Results available

Treating Childhood Apraxia of Speech

NCT03238677
Conditions
Childhood Apraxia of Speech
Interventions
Speech Motor Chaining without Biofeedback, Biofeedback, Distributed Practice, Massed --> Distributed Practice
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
9 Years to 17 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Syracuse, New York
Conditions
Apraxia of Speech
Interventions
Soterix 1x1 line tDCS low-intensity stimulator, Sham
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 99 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
2
States / cities
New York, New York • White Plains, New York
Conditions
PPA, Non-fluent Aphasia, Apraxia of Speech, Primary Progressive Non-fluent Aphasia, Primary Progressive Aphasia
Interventions
AV-1451
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Developmental Verbal Dyspraxia, Autism Spectrum Disorder
Interventions
CAS Treatment for Minimally Verbal Children with Autism
Behavioral
Lead sponsor
MGH Institute of Health Professions
Other
Eligibility
5 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Apraxia of Speech, Aphasia, Acquired, Speech Disorders
Interventions
EPG Tx, SPT
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Apraxia of Speech, Aphasia
Interventions
Combined Aphasia and Apraxia of Speech Treatment (CAAST)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 75 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Salt Lake City, Utah
Completed Not applicable Interventional Results available

Brain Biomarkers of Response to Treatment for Apraxia of Speech

NCT02046941
Conditions
Aphasia, Stroke
Interventions
Speech Production Treatment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 90 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Sacramento, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Video Assisted Speech Technology to Enhance Motor Planning for Speech

NCT04764539
Conditions
Autism Spectrum Disorder, Apraxia of Speech
Interventions
Video Assisted Speech Therapy (VAST)
Behavioral
Lead sponsor
iTherapy, LLC
Other
Eligibility
4 Years to 8 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Vallejo, California
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Brain-based Understanding of Individual Language Differences After Stroke

NCT04991519
Conditions
Aphasia, Stroke, Alexia
Interventions
Not listed
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Completed Phase 1 Interventional Accepts healthy volunteers Results available

ASSIST: Treatment for Childhood Apraxia of Speech

NCT03903120
Conditions
Childhood Apraxia of Speech
Interventions
ASSIST
Behavioral
Lead sponsor
Temple University
Other
Eligibility
4 Years to 9 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Apraxia Speech
Interventions
Transcranial Magnetic Stimulation (TMS)
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Miami, Florida
Conditions
Stroke, Aphasia, Apraxia of Speech
Interventions
Startle Adjuvant Rehabilitation Therapy (START)
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 100 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Tempe, Arizona
Conditions
Apraxia of Speech, Non-fluent Aphasia, Primary Progressive Aphasia, Primary Progressive Nonfluent Aphasia
Interventions
Testing protocol for the study
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Completed Not applicable Interventional Accepts healthy volunteers Results available

Investigating the Effects of Rhythm and Entrainment on Fluency in People With Aphasia

NCT05248295
Conditions
Aphasia, Apraxia of Speech
Interventions
Unison speech (vs. solo), Metrical timing (vs. conversational)
Behavioral
Lead sponsor
MGH Institute of Health Professions
Other
Eligibility
18 Years to 80 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Childhood Apraxia of Speech, Verbal Apraxia, Autism
Interventions
Omega-DEK, L-carnitine, Placebo
Drug
Lead sponsor
Claudia R. Morris
Other
Eligibility
2 Years to 6 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Atlanta, Georgia
Active, not recruiting Not applicable Interventional

Dose Frequency RCT on DTTC in Children With CAS

NCT05675306
Conditions
Childhood Apraxia of Speech
Interventions
Dynamic Temporal and Tactile Cueing Treatment
Behavioral
Lead sponsor
Marquette University
Other
Eligibility
30 Months to 95 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Recruiting No phase listed Observational Accepts healthy volunteers

ReadMap: Reading in Stroke Alexia and Typical Aging

NCT06700005
Conditions
Aphasia, Stroke, Alexia
Interventions
Not listed
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Completed Not applicable Interventional Results available

Treatments of Acquired Apraxia of Speech

NCT01483807
Conditions
Aphasia, Apraxia of Speech, Stroke
Interventions
Sound Production Treatment - Blocked, Sound Production Treatment - Random
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Salt Lake City, Utah
Recruiting Not applicable Interventional

Measuring Aided Language Development

NCT06512168
Conditions
Down Syndrome, Cerebral Palsy, Apraxia of Speech, Speech Sound Disorder, Speech Disorders in Children, Speech and Language Disorder
Interventions
AAC Generative Language Intervention
Behavioral
Lead sponsor
University of Central Florida
Other
Eligibility
42 Months to 60 Months
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Orlando, Florida
Conditions
PSP, CBD, PCA, LPA, Semantic Dementia, Semantic Aphasia, Behavioral Variant of Frontotemporal Dementia, FTD, PPA, Apraxia of Speech, MSA - Multiple System Atrophy, Parkinson Disease
Interventions
C-11 PiB, AV1451 Tau, C-11 ER176
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2050
U.S. locations
1
States / cities
Rochester, Minnesota
Enrolling by invitation Not applicable Interventional

taVNS for Speech and Language Recovery in Aphasia

NCT07563387
Conditions
Aphasia, Apraxia of Speech
Interventions
taVNS, sham taVNS
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Jacksonville, Florida
Conditions
Cerebral Palsy, Hydrocephalus, Apraxia of Speech, Hypoxia Ischemia, Cerebral, Drowning; Anoxia
Interventions
Cord Blood Infusion
Biological
Lead sponsor
Joanne Kurtzberg, MD
Other
Eligibility
Up to 26 Years
U.S. locations
2
States / cities
New Brunswick, New Jersey • Durham, North Carolina
Completed Not applicable Interventional Results available

Treatment Intensity - Apraxia of Speech

NCT02332915
Conditions
Aphasia, CVA, Apraxia of Speech
Interventions
Sound Production Treatment (SPT)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 90 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Salt Lake City, Utah