- Conditions
- Very Low Birth Weight Infants
- Interventions
- application of mother's own colostrum, application of sterile water
- Other
- Lead sponsor
- Milton S. Hershey Medical Center
- Other
- Eligibility
- Up to 3 Days
- Enrollment
- 43 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2013
- U.S. locations
- 1
- States / cities
- Hershey, Pennsylvania
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Showing 25–48
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- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Respiratory Distress Syndrome (RDS), Sepsis, Pneumonia, Hypertension, Pulmonary
- Interventions
- Inhaled nitric oxide, Placebo
- Drug
- Lead sponsor
- NICHD Neonatal Research Network
- Network
- Eligibility
- Up to 120 Hours
- Enrollment
- 420 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2006
- U.S. locations
- 17
- States / cities
- Birmingham, Alabama • Palo Alto, California • San Diego, California + 14 more
- Conditions
- Prematurity
- Interventions
- Amino acids
- Drug
- Lead sponsor
- Women and Infants Hospital of Rhode Island
- Other
- Eligibility
- Up to 18 Hours
- Enrollment
- 168 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2016
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Sepsis
- Interventions
- IVIG, Placebo
- Drug
- Lead sponsor
- NICHD Neonatal Research Network
- Network
- Eligibility
- Up to 72 Hours
- Enrollment
- 2,416 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1988 – 1991
- U.S. locations
- 8
- States / cities
- Birmingham, Alabama • Washington D.C., District of Columbia • Miami, Florida + 5 more
- Conditions
- Infant, Premature, Erythropoietin, Brain Injury, Intraventricular Hemorrhage, Periventricular Leukomalacia, Neurodevelopmental Outcomes, Randomized Clinical Trial
- Interventions
- Erythropoietin, Saline placebo
- Drug
- Lead sponsor
- Atlantic Health System
- Other
- Eligibility
- Up to 24 Hours
- Enrollment
- 22 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2010
- U.S. locations
- 1
- States / cities
- Morristown, New Jersey
- Conditions
- Bronchopulmonary Dysplasia, Very Low Birth Weight Infant, Prematurity
- Interventions
- Enrollment
- Other
- Lead sponsor
- Christiana Care Health Services
- Other
- Eligibility
- 1 Month to 7 Months
- Enrollment
- 78 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Newark, Delaware
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Electroencephalography
- Interventions
- Not listed
- Lead sponsor
- NICHD Neonatal Research Network
- Network
- Eligibility
- Up to 72 Hours
- Enrollment
- 102 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 8
- States / cities
- Palo Alto, California • Atlanta, Georgia • Detroit, Michigan + 4 more
- Conditions
- Tissue Oxygenation
- Interventions
- Resonance Raman Spectroscopy (RPS)
- Device
- Lead sponsor
- University of Florida
- Other
- Eligibility
- Not listed
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Very Low Birth Weight Infant
- Interventions
- FlexiMitt
- Device
- Lead sponsor
- Wyss Institute at Harvard University
- Other
- Eligibility
- 13 Months to 60 Months
- Enrollment
- 33 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2021
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts
- Conditions
- Preterm Infant, Early-Onset Neonatal Sepsis, Umbilical Cord
- Interventions
- Placental/Umbilical Cord Blood sample
- Other
- Lead sponsor
- The University of Texas Medical Branch, Galveston
- Other
- Eligibility
- Up to 1 Day
- Enrollment
- 65 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Galveston, Texas
- Conditions
- Infant Respiratory Distress Syndrome, Respiratory Insufficiency, Apnea of Prematurity
- Interventions
- Nasal high frequency ventilation
- Other
- Lead sponsor
- Tarah T Colaizy
- Other
- Eligibility
- 7 Days to 3 Months
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Premature; Infant, Enteral Nutrition, Human Milk, Fortification
- Interventions
- Human milk fortifiers
- Dietary Supplement
- Lead sponsor
- University of Tennessee
- Other
- Eligibility
- 2 Days to 7 Days
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Memphis, Tennessee
- Conditions
- Infection
- Interventions
- Not listed
- Lead sponsor
- Duke University
- Other
- Eligibility
- 1 Hour to 1 Week
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Interventions
- Standard Cord Clamping, Delayed Cord Clamping
- Procedure
- Lead sponsor
- NICHD Neonatal Research Network
- Network
- Eligibility
- Up to 1 Minute
- Enrollment
- 54 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2000
- U.S. locations
- 4
- States / cities
- Birmingham, Alabama • Cincinnati, Ohio • Cleveland, Ohio + 1 more
- Conditions
- Infant, Very Low Birth Weight, Infant, Premature, Diseases, Cerebral Hemorrhage
- Interventions
- Not listed
- Lead sponsor
- University of Arkansas
- Other
- Eligibility
- 1 Hour to 7 Days
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2008
- U.S. locations
- 1
- States / cities
- Little Rock, Arkansas
- Conditions
- Pneumococcal Infections, Streptococcus Pneumoniae, Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Interventions
- Not listed
- Lead sponsor
- NICHD Neonatal Research Network
- Network
- Eligibility
- Up to 3 Months
- Enrollment
- 368 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2004 – 2009
- U.S. locations
- 10
- States / cities
- Birmingham, Alabama • Palo Alto, California • Miami, Florida + 6 more
- Conditions
- Respiratory Distress Syndrome
- Interventions
- PSV+VG mode versus SIMV+VG mode
- Procedure
- Lead sponsor
- Children's Hospitals and Clinics of Minnesota
- Other
- Eligibility
- 72 Hours to 120 Hours
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Infant, Newborn, Diseases, Other Preterm Infants, Infant, Small for Gestational Age, Premature Birth, Bronchopulmonary Dysplasia, Retinopathy of Prematurity
- Interventions
- Surfactant, Continuous Positive Airway Pressure (CPAP), Supplemental oxygen with target saturation of 85 to 89%, Supplemental oxygen with target saturation of 91 to 95%
- Drug · Device
- Lead sponsor
- NICHD Neonatal Research Network
- Network
- Eligibility
- 24 Weeks to 27 Weeks
- Enrollment
- 1,316 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2016
- U.S. locations
- 22
- States / cities
- Birmingham, Alabama • Palo Alto, California • San Diego, California + 18 more
- Conditions
- Infant, Very Low Birth Weight
- Interventions
- Similac special care 30, Similac human milk fortifier
- Dietary Supplement
- Lead sponsor
- University of Oklahoma
- Other
- Eligibility
- 1 Day to 10 Weeks
- Enrollment
- 84 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2010
- U.S. locations
- 1
- States / cities
- Oklahoma City, Oklahoma
- Conditions
- Sepsis
- Interventions
- HeRO heart rate characteristics monitor
- Device
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 1 Day to 32 Weeks
- Enrollment
- 3,003 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2011
- U.S. locations
- 8
- States / cities
- Birmingham, Alabama • Miami, Florida • Orlando, Florida + 5 more
- Conditions
- Breast Milk Expression
- Interventions
- Early initiation, Intermediate expression, Late initiation
- Behavioral
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 180 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2017
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Prematurity
- Interventions
- preterm infant formula with high protein levels, preterm standard infant formula
- Other
- Lead sponsor
- Société des Produits Nestlé (SPN)
- Industry
- Eligibility
- 1 Day to 10 Weeks
- Enrollment
- 70 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2012
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Ductus Arteriosus, Patent
- Interventions
- Nondisclosure of screening echocardiogram results, Disclosure of screening echocardiogram results
- Other
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- Up to 72 Hours
- Enrollment
- 88 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 2
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Neurodevelopmental Outcomes of VLBW Infants
- Interventions
- Donor Human Milk
- Dietary Supplement
- Lead sponsor
- Tarah T Colaizy
- Other
- Eligibility
- Up to 24 Months
- Enrollment
- 121 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2016
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa