Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 13, 2026, 10:06 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 127 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Very Preterm Infant Clear all

Conditions: Preterm Birth, Very Preterm Infant, Infant Development, Neonatal Intensive Care Unit
Interventions: Homebased SPEEDI, Telehealth SPEEDI; Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 0 Years to 6 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 2
States / cities: Minneapolis, Minnesota

Conditions: Infant Respiratory Distress Syndrome, Respiratory Insufficiency, Apnea of Prematurity
Interventions: Nasal high frequency ventilation; Other
Lead sponsor: Tarah T Colaizy; Other
Eligibility: 7 Days to 3 Months
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Iron Deficiency Anemia
Interventions: Ferrous Sulfate Oral Product; Drug
Lead sponsor: AdventHealth; Other
Eligibility: 29 Weeks to 33 Weeks
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Respiratory Distress Syndrome in Premature Infants, Very Low Birth Weight Baby
Interventions: iNO, Nitrogen; Drug · Other
Lead sponsor: University of Oklahoma; Other
Eligibility: 1 Minute to 2 Minutes
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 2
States / cities: Oklahoma City, Oklahoma

Conditions: Prematurity, VLBW - Very Low Birth Weight Infant
Interventions: Prepod, Joint compression exercises; Other · Procedure
Lead sponsor: Asante Health System; Other
Eligibility: 32 Weeks to 36 Weeks
Enrollment: 54 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Medford, Oregon

Conditions: Infant, Premature, Erythropoietin, Brain Injury, Intraventricular Hemorrhage, Periventricular Leukomalacia, Neurodevelopmental Outcomes, Randomized Clinical Trial
Interventions: Erythropoietin, Saline placebo; Drug
Lead sponsor: Atlantic Health System; Other
Eligibility: Up to 24 Hours
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Morristown, New Jersey

Conditions: Bacteria Infection, Respiratory Tract Infections
Interventions: Azithromycin; Drug
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 1 Day to 3 Days
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Bronchopulmonary Dysplasia
Interventions: Montelukast; Drug
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 7 Days and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Ductus Arteriosus, Patent
Interventions: Nondisclosure of screening echocardiogram results, Disclosure of screening echocardiogram results; Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: Up to 72 Hours
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania

Conditions: Apnea of Prematurity
Interventions: NCPAP as mode for apnea prevention, NIPPV as rescue mode for apnea prevention; Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: Not listed
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Respiratory Insufficiency of Prematurity
Interventions: Titration of oxygen therapy; Other
Lead sponsor: McMaster University; Other
Eligibility: Up to 24 Hours
Enrollment: 1,201 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 3
States / cities: Stony Brook, New York • Philadelphia, Pennsylvania

Conditions: Gastric Residual Volume, Preterm Infant, Feeding Disorder Neonatal
Interventions: No Gastric residual volume monitoring; Other
Lead sponsor: AdventHealth; Other
Eligibility: 2 Hours to 1 Month
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Retinopathy of Prematurity, Bronchopulmonary Dysplasia (BPD)
Interventions: Inositol lower volume, Inositol higher volume, Placebo lower volume, Placebo higher volume; Drug
Lead sponsor: NICHD Neonatal Research Network; Network
Eligibility: 3 Days to 6 Days
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 11
States / cities: New Haven, Connecticut • Indianapolis, Indiana • Detroit, Michigan + 7 more

Conditions: Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Retinopathy of Prematurity, Blindness
Interventions: Supplemental Oxygen Management, Conventional Oxygen Management; Procedure
Lead sponsor: NICHD Neonatal Research Network; Network
Eligibility: Up to 48 Hours
Enrollment: 649 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1994 – 1999
U.S. locations: 9
States / cities: Palo Alto, California • New Haven, Connecticut • Atlanta, Georgia + 6 more

Conditions: Chronic Lung Disease
Interventions: gene variations; Genetic
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: Not listed
Enrollment: 1,100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2028
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Infant, Newborn, Diseases, Other Preterm Infants, Infant, Small for Gestational Age, Premature Birth, Bronchopulmonary Dysplasia, Retinopathy of Prematurity
Interventions: Surfactant, Continuous Positive Airway Pressure (CPAP), Supplemental oxygen with target saturation of 85 to 89%, Supplemental oxygen with target saturation of 91 to 95%; Drug · Device
Lead sponsor: NICHD Neonatal Research Network; Network
Eligibility: 24 Weeks to 27 Weeks
Enrollment: 1,316 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2016
U.S. locations: 22
States / cities: Birmingham, Alabama • Palo Alto, California • San Diego, California + 18 more

Conditions: Bronchopulmonary Dysplasia, Necrotizing Enterocolitis, Intraventricular Hemorrhage, Late Onset Neonatal Sepsis, Motor Skills Disorders
Interventions: delayed cord clamping; Procedure
Lead sponsor: University of Rhode Island; Other
Eligibility: Female only
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2006
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Preterm Birth
Interventions: Human milk fortifier; Dietary Supplement
Lead sponsor: Augusta University; Other
Eligibility: Up to 4 Days
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: Preterm Infant, Cerebral Palsy
Interventions: Supporting Play Exploration and Developmental Intervention (SPEEDI); Behavioral
Lead sponsor: University of Southern California; Other
Eligibility: Up to 6 Months
Enrollment: 85 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 2
States / cities: Los Angeles, California • Richmond, Virginia

Conditions: Preterm Infant, Early-Onset Neonatal Sepsis, Umbilical Cord
Interventions: Placental/Umbilical Cord Blood sample; Other
Lead sponsor: The University of Texas Medical Branch, Galveston; Other
Eligibility: Up to 1 Day
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Galveston, Texas

Conditions: Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Bronchopulmonary Dysplasia (BPD)
Interventions: Benchmarking Management Practices, Standard Management Practices; Other
Lead sponsor: NICHD Neonatal Research Network; Network
Eligibility: Up to 36 Weeks
Enrollment: 4,095 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2001 – 2004
U.S. locations: 17
States / cities: Birmingham, Alabama • Palo Alto, California • San Diego, California + 13 more

Conditions: Infant, Very Low Birth Weight
Interventions: Similac special care 30, Similac human milk fortifier; Dietary Supplement
Lead sponsor: University of Oklahoma; Other
Eligibility: 1 Day to 10 Weeks
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Preterm Infants
Interventions: 3-hour bundled care, 6-hour bundled care; Other
Lead sponsor: Duke University; Other
Eligibility: Up to 32 Weeks
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Enterocolitis, Necrotizing, Intestinal Perforation
Interventions: Laparotomy, Drainage; Procedure
Lead sponsor: NICHD Neonatal Research Network; Network
Eligibility: Up to 8 Weeks
Enrollment: 529 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2019
U.S. locations: 22
States / cities: Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 18 more

Search by objective public record fields.

NICU-to-Home Dyadic Support for Very Preterm Infants and Families

Nasal High Frequency Ventilation in Preterm Infants: A Pilot Study

Donor Breast Milk 2

Inhaled Nitric Oxide (iNO) as an Adjunct to Neonatal Resuscitation

Self Regulated Physical Activity and Bone Growth Enhancement in Premature Infants

High-Dose Erythropoietin in Extremely Premature Infants to Prevent/Attenuate Brain Injury: A Phase II Study

Early Versus Expectant Treatment of Ureaplasma Infection in Very Low Birth Weight Neonates

Montelukast in Very Low Birthweight Infants

Patent Ductus Arteriosus (PDA) Screening Trial

A Comparison of Non-invasive Ventilation Methods Used to Prevent Endotracheal Intubation Due to Apnea in Very Low Birth Weight Infants

Canadian Oxygen Trial (COT)

Routine Versus no Assessment of Gastric Residual Volumes in Preterm Infants

Single-Dose Intravenous Inositol Pharmacokinetics in Preterm Infants

Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of Prematurity

Genetic Variants and Susceptibility to Diseases of Prematurity in Very Low Birth-Weight Infants

Surfactant Positive Airway Pressure and Pulse Oximetry Trial

Effects of Delayed Cord Clamping in Very Low Birth Weight Infants

Human Milk in Preterm Infants

Does Timing Matter? Supporting Play, Exploration, and Early Developmental Intervention

Utility of Placental/Umbilical Cord Blood in Early Onset Neonatal Sepsis in Very Low Birth Weight Infants

Benchmarking Initiative to Reduce Bronchopulmonary Dysplasia

Liquid Preterm Formula Versus Powdered Human Milk Fortifier in VLBW Infants

Very Low Birth Weight Preterm Infant Bundled Care in the NICU

Laparotomy vs. Drainage for Infants With Necrotizing Enterocolitis