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Showing 25–45 of 21 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Virtual Reality Exposure Therapy Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

3D Video Virtual Reality Exposure Therapy Study

NCT02584387
View directory record Official record
Conditions
Acrophobia, Arachnophobia
Interventions
3D Video Virtual Reality Exposure Therapy
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 25, 2017 · Synced Sep 1, 2026, 11:03 PM EDT
Recruiting Not applicable Interventional

Virtual Reality-Enhanced Behavioral Activation for Older Adults With Depression

NCT07188623
View directory record Official record
Conditions
Depression - Major Depressive Disorder, Older Adults (65 Years and Older), Behavioral Activation Treatment, Virtual Reality Therapy
Interventions
VR-Enhanced BA
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
65 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 1, 2026, 11:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Virtual Reality System to Increase Access to Exposure Therapy for Anxiety and OCD

NCT02713516
View directory record Official record
Conditions
Anxiety, Obsessive Compulsive Disorder
Interventions
Virtual Reality
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
7 Years to 12 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 12, 2018 · Synced Sep 1, 2026, 11:03 PM EDT
Withdrawn Phase 2 Interventional

D-Cycloserine and Virtual Reality Exposure Therapy

NCT02933684
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
Seromycin, Virtual Reality Exposure Therapy, Placebo
Drug · Behavioral
Lead sponsor
Georgia State University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 12, 2018 · Synced Sep 1, 2026, 11:03 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Using Virtual Reality in Exposure-Based Treatment for Social Anxiety in Youth

NCT03135990
View directory record Official record
Conditions
Social Anxiety, Social Anxiety Disorder, Social Anxiety Disorder of Childhood
Interventions
Cognitive Behavioral Therapy with Virtual Reality Technology
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
13 Years to 23 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Sep 1, 2026, 11:03 PM EDT
Completed Not applicable Interventional Results available

Virtual Reality Therapy for Chronic Low Back Pain

NCT04409353
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Distraction-Based VR, Sham VR, Skills-Based VR, Activity Tracker
Device
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
13 Years and older
Enrollment
413 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Sep 1, 2026, 11:03 PM EDT
Completed Not applicable Interventional

Virtual Reality as a Tool to Lower Blood Pressure and Anxiety in Clinic Settings

NCT06960057
View directory record Official record
Conditions
White Coat Hypertension, Hypertension, Blood Pressure, Anxiety, Virtual Reality Exposure Therapy, Ambulatory Blood Pressure Monitoring, Blood Pressure Disorders
Interventions
Virtual Reality Exposure
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Sep 1, 2026, 11:03 PM EDT
Withdrawn Not applicable Interventional

Virtual Reality and D-Cycloserine in Combat Related Psycological Trauma in Burn Service Members

NCT00855153
View directory record Official record
Conditions
Psychological Trauma
Interventions
VR (Virtual reality), D-Cycloserine
Other · Drug
Lead sponsor
United States Army Institute of Surgical Research
Federal
Eligibility
18 Years to 45 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 19, 2011 · Synced Sep 1, 2026, 11:03 PM EDT
Terminated Not applicable Interventional

Embodied Virtual Reality Therapy for Functional Neurological Symptom/ Conversion Disorder

NCT02764476
View directory record Official record
Conditions
Conversion Disorder, Psychogenic Movement Disorder, Functional Movement Disorder, Functional Neurological Disorder, Non-epileptic Seizures
Interventions
Embodied Virtual Reality Therapy, Virtual reality
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 29, 2023 · Synced Sep 1, 2026, 11:03 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Modifying Virtual Reality Analgesia With Low-Dose Pain Medication

NCT01840774
View directory record Official record
Conditions
Virtual Reality Therapy
Interventions
Low-dose pain medication (Ketalar) and saline placebo
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 25, 2013 · Synced Sep 1, 2026, 11:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating VR Therapy Using Cold Pressor Test

NCT03268863
View directory record Official record
Conditions
Pain
Interventions
Virtual Reality, Cold Pressor
Device · Other
Lead sponsor
Janet Vittone
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
2
States / cities
Scottsdale, Arizona • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 10, 2019 · Synced Sep 1, 2026, 11:03 PM EDT
Completed Phase 2 Interventional

Virtual Reality Intervention for Skill Acquisition Support in Autism Spectrum Disorder (ASD)

NCT05791071
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Floreo VR Building Social Connections, Sham
Device
Lead sponsor
Floreo, Inc.
Industry
Eligibility
4 Years to 10 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Thousand Oaks, California
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Sep 1, 2026, 11:03 PM EDT
Completed Phase 4 Interventional Results available

Dexamethasone Plus Virtual Reality Exposure Therapy for PTSD

NCT01965366
View directory record Official record
Conditions
PTSD
Interventions
Virtual reality exposure therapy, 0.5 mg DEX
Behavioral · Drug
Lead sponsor
Emory University
Other
Eligibility
21 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 11, 2018 · Synced Sep 1, 2026, 11:03 PM EDT
Completed Phase 1Phase 2 Interventional

Virtual Reality (VR) Therapy for Post-Traumatic Stress Disorder (PTSD)

NCT00992953
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Treatment as Usual, Virtual Reality Exposure with Stimulus Control
Behavioral
Lead sponsor
Office of Naval Research (ONR)
Federal
Eligibility
18 Years to 65 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
2
States / cities
Camp Pendlton, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 8, 2009 · Synced Sep 1, 2026, 11:03 PM EDT
Enrolling by invitation Not applicable Interventional

Use of Augmented Reality and Virtual Reality During Cognitive Behavioral Therapy for Needle Phobia

NCT07042074
View directory record Official record
Conditions
Needle Phobia, Virtual Reality, Cognitive Behavior Treatment
Interventions
Mixed reality (XR) Exposure Therapy
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
11 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 1, 2026, 11:03 PM EDT
Recruiting Not applicable Interventional

Pilot Study of Virtual Reality Therapy for Students With Anxiety

NCT05319509
View directory record Official record
Conditions
Anxiety
Interventions
gameChange
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 30 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Sep 1, 2026, 11:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Developing a Virtual Reality Training Tool for Exposure Therapy: Simulated Exposure Trainer (SET)

NCT06706245
View directory record Official record
Conditions
Low-immersion (Mobile Device), High-immersion (Head Mounted Display)
Interventions
SET-VR (computer), SET-VR (headset)
Behavioral
Lead sponsor
Bradley Hospital
Other
Eligibility
Not listed
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Sep 1, 2026, 11:03 PM EDT
Completed Not applicable Interventional

Virtual Reality Exposure Versus In Vivo Exposure for Fear of Heights

NCT04737915
View directory record Official record
Conditions
Fear of Heights, Acrophobia, Specific Phobia, Anxiety Disorder
Interventions
Exposure Therapy (In Vivo), Exposure Therapy (Virtual Reality)
Behavioral
Lead sponsor
University of Notre Dame
Other
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Notre Dame, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 7, 2021 · Synced Sep 1, 2026, 11:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise and Virtual Reality Exposure Therapy for Acrophobia

NCT02361203
View directory record Official record
Conditions
Fear of Heights
Interventions
Exercise
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 25 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 1, 2016 · Synced Sep 1, 2026, 11:03 PM EDT
Completed Not applicable Interventional Results available

Efficacy of Virtual Reality Exposure Therapy Scripts for Social Phobia

NCT04850989
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
Pico Goblin VR headset
Device
Lead sponsor
Penn State University
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 12, 2025 · Synced Sep 1, 2026, 11:03 PM EDT
Completed Phase 3 Interventional Results available

Enhancing Exposure Therapy for Post Traumatic Stress Disorder (PTSD): Virtual Reality and Imaginal Exposure With a Cognitive Enhancer

NCT01352637
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
DCS (D-Cycloserine ) + Prolonged Imaginal Exposure, DCS (D-Cycloserine ) + Virtual Reality Exposure, Placebo + Prolonged Imaginal Exposure, Placebo (sugar pill) + Virtual Reality Exposure
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 70 Years
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
5
States / cities
Long Beach, California • Los Angeles, California • Atlanta, Georgia + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2019 · Synced Sep 1, 2026, 11:03 PM EDT