Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 22, 2026, 12:17 AM EDT

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Showing 481–504 of 2,373 matching trials from the live ClinicalTrials.gov search.
Conditions
Non-proliferative Diabetic Retinopathy (NPDR), Open-angle Glaucoma (OAG), Normal Tension Glaucoma (NTG)
Interventions
QLS-111 Ophthalmic Solution (0.015%), QLS-111 Ophthalmic Solution (0.075%)
Drug
Lead sponsor
Qlaris Bio, Inc.
Industry
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Uveal Melanoma
Interventions
Darovasertib
Drug
Lead sponsor
IDEAYA Biosciences
Industry
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
10
States / cities
Scottsdale, Arizona • La Jolla, California • Palo Alto, California + 7 more
Conditions
Glaucoma
Interventions
Restasis, Endura (artificial tears)
Drug
Lead sponsor
Wills Eye
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Glaucoma, Glaucoma, Suspect
Interventions
Standard GAT, Fixed force GAT, Upright applanating prototype, Pneumotonometer
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Glaucoma
Interventions
Collection of trabecular meshwork tissue during surgery
Other
Lead sponsor
Wills Eye
Other
Eligibility
21 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Glaucoma, Ocular Hypertension
Interventions
Brimonidine ophthalmic solution 0.1%, Brimonidine ophthalmic solution 0.2%
Drug
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older
Enrollment
433 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
1
States / cities
Atlanta, Georgia
Completed Not applicable Interventional Results available

Comparison of Silicone and Porous Plate Ahmed Glaucoma Valves

NCT01883856
Conditions
Glaucoma
Interventions
Silicone plate Ahmed Glaucoma Valve (Model FP7), Porous Plate Ahmed Glaucoma Valve (Model M4)
Device
Lead sponsor
Peter Netland, MD
Other
Eligibility
18 Years to 80 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Charlottesville, Virginia
Completed Not applicable Interventional Accepts healthy volunteers Results available

DAILIES TOTAL1 Versus ACUVUE TruEye - Effects on the Biology of the Ocular Surface and Lid Margin

NCT02347631
Conditions
Soft Contact Lenses, Myopia
Interventions
Soft Contact Lens - Daily Disposable Alcon Dailies Total 1 and ACUVUE TruEye, Soft Contact Lens - Acuvue TruEye and Alcon DAILIES TOTAL 1.
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 38 Years
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Adult Refractory Complex Partial Seizures
Interventions
Sabril
Drug
Lead sponsor
Lundbeck LLC
Industry
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
22
States / cities
San Francisco, California • New Haven, Connecticut • Dover, Delaware + 19 more
Recruiting Phase 1 Interventional Accepts healthy volunteers

Home-based Vision Therapy

NCT06886737
Conditions
Convergence Insufficiency
Interventions
Virtual-reality convergence training game
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Glaucoma, Ocular Hypertension
Interventions
Latanoprost-PPDS
Drug
Lead sponsor
Mati Therapeutics Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Menlo Park, California
Conditions
Progressive Supranuclear Palsy, Corticobasal Degeneration
Interventions
Lithium
Drug
Lead sponsor
Westat
Other
Eligibility
40 Years to 80 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
8
States / cities
Chicago, Illinois • Louisville, Kentucky • Baltimore, Maryland + 4 more
Conditions
Glaucoma, Dry Eye Syndrome, Conjunctivitis
Interventions
Not listed
Lead sponsor
Robin, Alan L., M.D.
Individual
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Baltimore, Maryland
Completed No phase listed Observational Accepts healthy volunteers

A Patient Reported Ocular Comfort Assessment Comparing Bepreve to Lastacaft

NCT01339507
Conditions
Allergic Conjunctivitis
Interventions
Not listed
Lead sponsor
Cunningham, Derek N., O.D., P.A.
Individual
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Austin, Texas
Conditions
Glaucoma, Open Angle
Interventions
brimonidine, timolol
Drug
Lead sponsor
Chicago Center for Vision Research
Other
Eligibility
30 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2004
U.S. locations
12
States / cities
Little Rock, Arkansas • Gainesville, Florida • Palm Beach Gardens, Florida + 7 more
Completed Not applicable Interventional Results available

Beacon Sensors and Telerehabilitation for Low Vision

NCT04066075
Conditions
Low Vision
Interventions
Low Vision Rehabilitation
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
11
States / cities
Fullerton, California • Grass Valley, California • Los Angeles, California + 8 more
Conditions
Correction Vision Surgery, Cataract Surgery
Interventions
cataract surgery
Procedure
Lead sponsor
Utah Eye Centers
Other
Eligibility
Not listed
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Ogden, Utah
Conditions
Usher Syndrome, Retinitis Pigmentosa
Interventions
Not listed
Lead sponsor
National Center for Research Resources (NCRR)
NIH
Eligibility
0 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 1999
U.S. locations
1
States / cities
Portland, Oregon
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Approved and Investigational Contact Lenses

NCT02669095
Conditions
Visual Disorder
Interventions
Investigational Contact Lenses (Test), Marketed Contact Lenses (Control)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
4
States / cities
Sarasota, Florida • Winter Park, Florida • Pickens, South Carolina + 1 more
Conditions
Ocular Blood Flow
Interventions
Experimental, Placebo
Dietary Supplement
Lead sponsor
LycoRed Ltd.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Indianapolis, Indiana
Not listed No phase listed Observational Accepts healthy volunteers

Dynamic Vision Testing and Concussion Management Dream Team 65

NCT05326555
Conditions
Head Injury, Sport Injury, Concussion, Brain
Interventions
Dynamic Vision Testing (Bertec Vision Advantage System) and Balance Error Scoring System
Diagnostic Test
Lead sponsor
California State University, Northridge
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Northridge, California
Conditions
COPD
Interventions
Sulforaphane 25, Sulforaphane 150, Placebo
Drug · Dietary Supplement · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
40 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
3
States / cities
Baltimore, Maryland • Buffalo, New York • Philadelphia, Pennsylvania
Not listed No phase listed Observational Accepts healthy volunteers

Panoptix Trifocal Lens in Post Refractive Myopic Laser Vision Correction Surgery

NCT04698278
Conditions
Cataract, Refractive Errors
Interventions
PanOptix Trifocal Intraocular Lens
Device
Lead sponsor
Parkhurst NuVision Clinical Research LLC
Other
Eligibility
22 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Glaucoma, Cataract
Interventions
Cornea/Anterior Segment OCT CASIA2, Optovue RTVue XR Avanti
Device
Lead sponsor
Tomey Corporation
Industry
Eligibility
22 Years and older
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Andover, Massachusetts