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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Conditions
Dysphonia Resulting From Vocal Fold Scarring, Age-related Dysphonia
Interventions
Azficel-T (autologous fibroblasts), Placebo
Biological · Drug
Lead sponsor
Castle Creek Biosciences, LLC.
Industry
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
3
States / cities
Los Angeles, California • Stanford, California • New York, New York
Terminated Not applicable Interventional Accepts healthy volunteers

Effect of Vocal Exercise After Botulinum Toxin Injection for Spasmodic Dysphonia

NCT00895063
Conditions
Spasmodic Dysphonia, Dystonia
Interventions
Vocal Exercise
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
1
States / cities
New York, New York
Completed No phase listed Observational

Voice Changes During ECT

NCT04420793
Conditions
Unipolar Depression, Bipolar Depression, Bipolar Disorder, Manic
Interventions
Questionnaire
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 89 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Adductor Spasmodic Dysphonia
Interventions
Voice Exercise
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years to 70 Years · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Madison, Wisconsin
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

The Effect of IV NSAID's and Corticosteroids on Dysphasia and Dysphonia Following ASDF

NCT04650893
Conditions
Dysphagia, Dysphonia
Interventions
Intravenous Ketorolac, Intravenous Dexamethasone, Placebo
Drug
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Omaha, Nebraska
Conditions
Spasmodic Dysphonia, Adductor Spasmodic Dysphonia, Voice Disorders
Interventions
Sensation testing
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 85 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Francisco, California
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Investigation of the Role of Steroids in Enhancing Voice Therapy Outcomes

NCT02286960
Conditions
Dysphonia
Interventions
Steroid, Lactose Pills
Drug · Dietary Supplement
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
New York, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

Brain Network Changes After Vibro-tactile Stimulation in Laryngeal Dystonia

NCT07443891
Conditions
Laryngeal Dystonia
Interventions
Vibrotactile Stimulation (VTS)
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Completed No phase listed Observational

Neuropathology of Spasmodic Dysphonia

NCT00118586
Conditions
Voice Disorders, Spasmodic Dysphonia, Healthy, Movement Disorder, Focal Dystonia
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
21 Years and older
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2022
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Muscle Tension Dysphonia
Interventions
Standard of care voice therapy with novice clinician RTSS-Voice documentation, Standard of care voice therapy with expert clinician RTSS-Voice documentation
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
14 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
5
States / cities
Atlanta, Georgia • Boston, Massachusetts • New York, New York + 2 more
Conditions
Sore Throat, Dysphagia, Dysphonia
Interventions
Standard inflation of LMA cuff, Pressure check with syringe recoil, Pressure check by pressure transducer
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 99 Years
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Gainesville, Florida • Jacksonville, Florida
Conditions
Vocal Fold Nodules, Muscle Tension Dysphonia
Interventions
Ambulatory voice biofeedback
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

rTMS in Spasmodic Dysphonia

NCT02957942
Conditions
Spasmodic Dysphonia, Laryngeal Dystonia
Interventions
1Hz repetitive transcranial magnetic stimulation (rTMS)
Device
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Not listed No phase listed Observational Accepts healthy volunteers

A Study to Analyze Symptoms Prevalent in Early PD (Dysphonia, Tremor)

NCT04288804
Conditions
Parkinson Disease
Interventions
Smartphone microphone sensor, Smartphone accelerometer sensor
Device
Lead sponsor
Goalspal LLC
Other
Eligibility
Not listed
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Pleasanton, California
Recruiting Phase 3 Interventional Accepts healthy volunteers

Translaryngeal Vibration for Hyperfunctional Voice Disorders

NCT07145086
Conditions
Dysphonia, Muscle Tension Dysphonia
Interventions
Voice therapy with vibration
Behavioral
Lead sponsor
Texas Christian University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Fort Worth, Texas
Completed No phase listed Observational Accepts healthy volunteers

Brain Mapping of Voice Control

NCT00066911
Conditions
Voice Disorders
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
20 Years to 70 Years
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Laryngopharyngeal Reflux
Interventions
Lansoprazole, Sugar pill
Drug · Dietary Supplement
Lead sponsor
American Institute for Voice and Ear Research
Other
Eligibility
18 Years to 89 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
3
States / cities
Detroit, Michigan • Philadelphia, Pennsylvania • Houston, Texas
Conditions
Dysphonia, Unilateral Vocal Cord Paralysis
Interventions
Standard of care voice therapy, Expiratory muscle strength training (EMST)
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Miami, Florida
Conditions
Spasmodic Dysphonia, Laryngeal Dystonia
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Atlanta, Georgia • St Louis, Missouri
Conditions
Laryngeal Dystonia, Adductor Spastic Dysphonia of Dystonia
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
1
States / cities
Indianapolis, Indiana
Terminated No phase listed Observational Accepts healthy volunteers

Central Mechanisms in Speech Motor Control Studied With H215O PET

NCT00001308
Conditions
Communication Disorder, Healthy, Stuttering, Tourette Syndrome, Voice Disorder
Interventions
Not listed
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
18 Years to 85 Years
Enrollment
1,163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1992 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Not applicable Interventional Accepts healthy volunteers Results available

No Post Intubation Laryngeal Symptoms

NCT05383417
Conditions
Sore-throat, Dysphonia, Dysphagia, Intubation Complication, Anesthesia Intubation Complication, Anesthesia Morbidity, Anesthesia Complication, Anesthesia; Adverse Effect, Anesthesia; Reaction, Throat Disorder, Throat; Wound, Throat Injury
Interventions
EndoClip
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
La Jolla, California
Conditions
Voice and Resonance Disorders, Vocal Fold Polyp, Vocal Cord Cyst, Vocal Cord Polyp, Atrophy of Vocal Cord
Interventions
Inclusion of semi-occluded mask in voice therapy
Device
Lead sponsor
Jacqueline Gartner-Schmidt
Other
Eligibility
18 Years to 60 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Dystonia
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
3,265 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
34
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Fountain Valley, California + 26 more