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Showing 1–24 of 31 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Volatile Organic Compounds Clear all
Recruiting No phase listed Observational Accepts healthy volunteers

Using Urine Samples to Identify Lung Cancer

NCT06033248
View directory record Official record
Conditions
Non Small Cell Lung Cancer
Interventions
urine sample
Diagnostic Test
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 90 Years
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 3, 2026, 6:52 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Tuberculosis Volatile Organic Compounds

NCT01379066
View directory record Official record
Conditions
Pulmonary Tuberculosis
Interventions
Not listed
Lead sponsor
Landon Pediatric Foundation
Other
Eligibility
1 Year to 40 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
2
States / cities
Oxnard, California • Ventura, California
Source: ClinicalTrials.gov public record
Updated Aug 12, 2014 · Synced Sep 3, 2026, 6:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of a Proprietary Dietary Supplement on Fecal Volatile Organic Compounds

NCT02871596
View directory record Official record
Conditions
Healthy
Interventions
Placebo, Flavonoids, Flavonoids+Prebiotics
Other · Dietary Supplement
Lead sponsor
Pharmanex
Industry
Eligibility
18 Years to 70 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Logan, Utah
Source: ClinicalTrials.gov public record
Updated Feb 22, 2017 · Synced Sep 3, 2026, 6:52 AM EDT
Completed Not applicable Interventional

Temporal Variation in Exhaled Volatile Organic Compounds in Esophageal Cancer Patients

NCT06453993
View directory record Official record
Conditions
Esophageal Cancer
Interventions
Exhaled VOC breath test
Other
Lead sponsor
Benaroya Research Institute
Other
Eligibility
18 Years to 90 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 26, 2024 · Synced Sep 3, 2026, 6:52 AM EDT
Completed No phase listed Observational Results available

Home Air Quality Impact for Adults With Asthma

NCT05224076
View directory record Official record
Conditions
Asthma, Environmental Exposure, Home Environment Related Disease
Interventions
Home Air Quality
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Sep 3, 2026, 6:52 AM EDT
Completed No phase listed Observational

Biomarkers in Exhaled Breath of Glucose Fluctuation in Type 1 Diabetes

NCT03435198
View directory record Official record
Conditions
Volatile Organic Compounds, Hypoglycemia, Type 1 Diabetes Mellitus
Interventions
Collect exhaled breath during low and normal blood sugar
Diagnostic Test
Lead sponsor
East Tennessee State University
Other
Eligibility
5 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Johnson City, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 14, 2019 · Synced Sep 3, 2026, 6:52 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Breath Analysis in Early Stage Lung Cancer Using Infrared Spectroscopy

NCT04556435
View directory record Official record
Conditions
Lung Cancer, Non Small Cell Lung Cancer
Interventions
Not listed
Lead sponsor
Breathe BioMedical Inc
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 3, 2026, 6:52 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Volatile Organic Compounds in Staphylococcus Aureus Patients

NCT01379053
View directory record Official record
Conditions
Staphylococcus Aureus, Methicillin-resistant Staphylococcus Aureus, Nosocomial Disease
Interventions
Not listed
Lead sponsor
Landon Pediatric Foundation
Other
Eligibility
1 Year to 85 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Ventura, California
Source: ClinicalTrials.gov public record
Updated Aug 12, 2014 · Synced Sep 3, 2026, 6:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Validating eNose Measurement of Daily Fiber Intake

NCT05634044
View directory record Official record
Conditions
Dietary Fiber
Interventions
eNose Device
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 28, 2024 · Synced Sep 3, 2026, 6:52 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

NanoSpectrometer Biomarker Discovery and Confirmation Study

NCT03275688
View directory record Official record
Conditions
Lung Cancer
Interventions
Breath Analysis
Diagnostic Test
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
332 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 21, 2020 · Synced Sep 3, 2026, 6:52 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Analysis of Volatile Chemicals in Lung Cancer Screen-Eligible Subjects Using Infrared Spectroscopy

NCT05174468
View directory record Official record
Conditions
Lung Cancer
Interventions
Not listed
Lead sponsor
Breathe BioMedical Inc
Industry
Eligibility
50 Years to 80 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 3, 2026, 6:52 AM EDT
Not listed No phase listed Observational

Breath Test for Biomarkers in Humans Receiving Total Body Irradiation

NCT02152722
View directory record Official record
Conditions
Radiation Injury
Interventions
Not listed
Lead sponsor
Menssana Research, Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
3
States / cities
Atlanta, Georgia • Hackensack, New Jersey • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 6, 2015 · Synced Sep 3, 2026, 6:52 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Organic Compounds and Postoperative Delirum

NCT05875220
View directory record Official record
Conditions
Identify Postoperative Delirium Using Exhaled Gas Patterns
Interventions
No intervention
Other
Lead sponsor
University of Virginia
Other
Eligibility
65 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Sep 3, 2026, 6:52 AM EDT
Completed No phase listed Observational

Breath Test for Chemicals (Volatile Organic Compounds)

NCT01437033
View directory record Official record
Conditions
Breath Tests, Human Volunteers, Pilot Study
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
30 Years to 60 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Sep 3, 2026, 6:52 AM EDT
Terminated No phase listed Observational

Analysis of Volatile Organic Compounds in the Breath of Lung Transplant Rejection Patients Using Infrared Spectroscopy

NCT06309628
View directory record Official record
Conditions
Lung Transplant Rejection
Interventions
Breathe sample
Diagnostic Test
Lead sponsor
Paragonix Technologies
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Sep 3, 2026, 6:52 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Testing Spectrosense EVA System for Detection of Breast Cancer by Analyzing Volatile Organic Compounds (VOCs) in Exhaled Air

NCT01849328
View directory record Official record
Conditions
Breast Cancer
Interventions
Not listed
Lead sponsor
Rauscher, Gregory E., M.D. PA
Individual
Eligibility
18 Years and older · Female only
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2013
U.S. locations
1
States / cities
Englewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 18, 2013 · Synced Sep 3, 2026, 6:52 AM EDT
Not yet recruiting No phase listed Observational Accepts healthy volunteers

Analysis of Breath Volatile Organic Compounds Using Mass Spectrometry

NCT07732686
View directory record Official record
Conditions
Pancreas Cancer, Hepatocellular Carcinoma, Lung Cancer, Ovarian Cancer, Breast Cancer, Head and Neck Cancer, Colon Cancer, Bladder Cancer, Other Cancer
Interventions
Proton Transfer Reaction Mass Spectrometry Analysis
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 3, 2026, 6:52 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Identifying Patterns in the Breath of Individuals With Breast Cancer

NCT06512350
View directory record Official record
Conditions
Breast Cancer
Interventions
Not listed
Lead sponsor
Breathe BioMedical Inc
Industry
Eligibility
40 Years to 74 Years · Female only
Enrollment
5,175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Jacksonville, Florida • Durham, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Sep 3, 2026, 6:52 AM EDT
Active, not recruiting No phase listed Observational

Lipidomics, Proteomics, Micro RNAs and Volatile Organic Compounds (VOC)

NCT02531607
View directory record Official record
Conditions
Pancreatic Neoplasms
Interventions
blood and bile
Other
Lead sponsor
AdventHealth
Other
Eligibility
19 Years to 95 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2026
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 3, 2026, 6:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Work Should Not Hurt You: Reduction of Hazardous Exposures in Small Businesses Through a Community Health Worker Intervention

NCT03455530
View directory record Official record
Conditions
Community Health Aides, Industrial Hygiene, Volatile Organic Compounds
Interventions
Industrial Hygiene-Enhance Community Health Worker Intervention
Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
268 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 9, 2025 · Synced Sep 3, 2026, 6:52 AM EDT
Recruiting Not applicable Interventional

Addressing Tetrachloroethylene Exposure in an Impacted Community

NCT05819996
View directory record Official record
Conditions
Vapors; Inhalation, Cancer, Volatile Organic Compounds
Interventions
Environmental educational campaign
Behavioral
Lead sponsor
Purdue University
Other
Eligibility
18 Years to 99 Years
Enrollment
510 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 17, 2025 · Synced Sep 3, 2026, 6:52 AM EDT
Completed Not applicable Interventional

Humidified Forest Oils for Immune System Recovery in Stage I-III Breast or Prostate Cancer

NCT05012813
View directory record Official record
Conditions
Breast Carcinoma, Prostate Carcinoma
Interventions
Aromatherapy with Essential Oils
Other
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Sep 3, 2026, 6:52 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Testing Spectrosense EVA System for Detection of Pancreatic Cancer by Analyzing Volatile Organic Compounds (VOCs) in Exhaled Air

NCT01994681
View directory record Official record
Conditions
Pancreatic Cancer
Interventions
Not listed
Lead sponsor
Rauscher, Gregory E., M.D. PA
Individual
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2013
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 4, 2013 · Synced Sep 3, 2026, 6:52 AM EDT
Completed No phase listed Observational

Exploratory Study of Volatile Organic Compounds in Alveolar Breath

NCT03451994
View directory record Official record
Conditions
Nutritional and Metabolic Diseases
Interventions
Breath test
Other
Lead sponsor
Mebo Research, Inc.
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Oct 13, 2020 · Synced Sep 3, 2026, 6:52 AM EDT