Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 2, 2026, 3:22 PM EDT

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Showing 1–24 of 31 matching trials from the live ClinicalTrials.gov search.
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Conditions
Eating Behaviors
Interventions
No water, Water, Low Moisture, High moisture
Other
Lead sponsor
Cornell University
Other
Eligibility
20 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Ithaca, New York
Completed Not applicable Interventional Accepts healthy volunteers

Water Intervention for Thinking in Kids (WITiKids ) Study

NCT02816450
Conditions
Low Fluid Intake, Chronic
Interventions
Water Intake
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
9 Years to 10 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Urbana, Illinois
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Effect of Low Water Intake on Glucose Regulation Measured Using Continuous Glucose Monitoring

NCT06645431
Conditions
Blood Glucose Concentration, Blood Glucose Self Monitoring
Interventions
Water Intake
Behavioral
Lead sponsor
California Polytechnic State University-San Luis Obispo
Other
Eligibility
18 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Luis Obispo, California
Recruiting Not applicable Interventional Accepts healthy volunteers

Thirst for Knowledge

NCT07670767
Conditions
Geriatric Population
Interventions
Education with a regular hydration opportunity
Behavioral
Lead sponsor
Duquesne University
Other
Eligibility
60 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Cornwall, Pennsylvania
Conditions
Cardiovascular Diseases, Hypertension, Diet
Interventions
Energy Drink, Water Control
Dietary Supplement · Other
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
18 Years to 30 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Arlington, Texas
Conditions
Healthy Nutrition, Culinary Medicine, Sodium Excess
Interventions
Salt replacement seasoning (50% salt and 50% MSG) mix, Salt replacement seasoning (70% salt and 30% MSG) mix, NaCl (sodium chloride/table salt)
Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Lubbock, Texas
Conditions
Dehydration, Diabetes Mellitus, Type 2
Interventions
Water Intake
Other
Lead sponsor
Arizona State University
Other
Eligibility
30 Years to 55 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Phoenix, Arizona
Conditions
Dehydration, Mood
Interventions
Increase water consumption, Maintain adequate water consumption
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 35 Years
Enrollment
217 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Phoenix, Arizona
Recruiting Not applicable Interventional Accepts healthy volunteers

Water Intake and Weight Control in Older Adults

NCT05843318
Conditions
Overweight and Obesity
Interventions
Water intake and weight control in older adults - Premeal Water + hypocaloric diet, Water intake and weight control in older adults - Total Daily Water + hypocaloric diet, Water Intake and weight control in older adults - hypocaloric diet alone
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
50 Years and older
Enrollment
375 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Blacksburg, Virginia
Conditions
Radiation Toxicity, Recurrent Breast Cancer, Stage I Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer, Stage IIIC Breast Cancer, Stage IV Breast Cancer
Interventions
alkaline water, distilled water, external beam radiation therapy (EBRT)
Dietary Supplement · Radiation
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Westlake, Ohio
Conditions
Obesity
Interventions
Healthy Drinks, Healthy Futures
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
2 Years to 105 Years
Enrollment
1,034 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Stanford, California
Conditions
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Interventions
Diet and water adjustment
Behavioral
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Obesity
Interventions
Drink Tap
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
Not listed
Enrollment
1,038 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Stanford, California
Conditions
Dehydration
Interventions
Not listed
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 65 Years
Enrollment
492 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Phoenix, Arizona
Completed Not applicable Interventional Accepts healthy volunteers

Oral Water Hydration to Prevent Post-Vaccination Presyncope

NCT02353390
Conditions
Presyncope, Syncope
Interventions
Oral Water Hydration
Other
Lead sponsor
Duke University
Other
Eligibility
11 Years to 21 Years
Enrollment
1,820 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts • Durham, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

A Community-based Study to Target Childhood Obesity

NCT02890056
Conditions
Obesity
Interventions
H2GO!
Behavioral
Lead sponsor
Boston University
Other
Eligibility
9 Years to 12 Years
Enrollment
207 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Obesity, Adolescent, PreDiabetes
Interventions
Unsweetened flavored sparkling water
Other
Lead sponsor
Indiana University
Other
Eligibility
10 Years to 21 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Bloomington, Indiana
Conditions
Water Intake
Interventions
Air Up® Peach Pod, Air Up® Orangeade Pod
Dietary Supplement
Lead sponsor
air up GmbH
Industry
Eligibility
18 Years to 50 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Santa Monica, California
Conditions
Dehydration
Interventions
Exercise Intervention
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

A Cluster Randomized Trial of the H2GO! Program

NCT04265794
Conditions
Childhood Obesity
Interventions
H2GO!
Behavioral
Lead sponsor
Boston University
Other
Eligibility
9 Years and older
Enrollment
824 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Hydration on Gut Health and Thinking

NCT05315531
Conditions
Dehydration, Cognitive Change, Gastrointestinal Microbiota
Interventions
Water Intake
Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
19 Years to 50 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Urbana, Illinois
Completed Phase 1 Interventional Accepts healthy volunteers

A Water Consumption Study of ALKS 5461 in Healthy Volunteers

NCT02521857
Conditions
Healthy
Interventions
ALKS 5461
Drug
Lead sponsor
Alkermes, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Overland Park, Kansas
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Sodium Intake on Calcium Retention in Girls

NCT01564238
Conditions
Osteoporosis
Interventions
Low Na diet (1.3 g/d), High sodium diet (3.8 g/d)
Other
Lead sponsor
Purdue University
Other
Eligibility
11 Years to 15 Years · Female only
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2000
U.S. locations
1
States / cities
West Lafayette, Indiana
Completed Not applicable Interventional Accepts healthy volunteers Results available

High Water Intake to Slow Progression of Polycystic Kidney Disease

NCT00784030
Conditions
Kidney, Polycystic, Autosomal Dominant
Interventions
Water
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
New York, New York