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ClinicalTrials.gov public records Last synced Oct 1, 2026, 10:55 PM EDT

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Showing 49–72 of 1,561 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Weight Change, Body Clear all
Completed Not applicable Interventional

Using Technology to Investigate Lapses in a Weight Loss Program Among Individuals With Overweight and Obesity

NCT06023537
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Behavioral weight loss program
Behavioral
Lead sponsor
Williams College
Other
Eligibility
18 Years to 65 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Williamstown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 1, 2026, 10:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Calcium Supplementation for a Healthy Weight-Lite (CaSHeW Lite)

NCT00386672
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Reduced energy (lite) OJ fortified with Calcium and Vitamin D, Nutrition Counseling, Reduced energy (lite) OJ without Calcium and Vitamin D
Dietary Supplement · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Oct 1, 2026, 10:55 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Opt-IN: Optimization of Remotely Delivered Intensive Lifestyle Treatment for Obesity

NCT01814072
View directory record Official record
Conditions
Weight Loss
Interventions
12 Telephone Coaching Sessions, 24 Telephone Coaching Sessions, Report to Primary Care Physician, Text Messages, Recommendations to use meal replacements, Buddy Training
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years
Enrollment
562 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 1, 2023 · Synced Oct 1, 2026, 10:55 PM EDT
Completed Not applicable Interventional

Mood and Nutrition Interventions in Polycystic Ovary Syndrome

NCT01899001
View directory record Official record
Conditions
Polycystic Ovary Syndrome (PCOS)
Interventions
Cognitive Behavioral Therapy, Nutrition Counseling
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 23, 2016 · Synced Oct 1, 2026, 10:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep-Safe: A Strong African American Families Study

NCT03505203
View directory record Official record
Conditions
Weight Gain
Interventions
Sleep Soothe, Sleep Safe
Behavioral
Lead sponsor
University of Georgia
Other
Eligibility
17 Years and older
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Oct 1, 2026, 10:55 PM EDT
Completed Phase 4 Interventional

Examining the Effect of Ondansetron on Bowel Prep Success

NCT05439772
View directory record Official record
Conditions
Abdominal Pain, Inflammatory Bowel Diseases, Eosinophilic Gastroenteritis, Diarrhea, Hematochezia, Weight Loss
Interventions
Ondansetron
Drug
Lead sponsor
State University of New York - Downstate Medical Center
Other
Eligibility
2 Years to 20 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Oct 1, 2026, 10:55 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Comparison of Two Approaches to Weight Loss Follow-Up Study

NCT00143962
View directory record Official record
Conditions
Obesity
Interventions
Low Carbohydrate Diet
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
3
States / cities
Denver, Colorado • St Louis, Missouri • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 17, 2016 · Synced Oct 1, 2026, 10:55 PM EDT
Completed Phase 1 Interventional

Effects of Betahistine Hydrochloride in Overweight Women

NCT00459992
View directory record Official record
Conditions
Obesity, Overweight, Overnutrition
Interventions
Betahistine Hydrochloride
Drug
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years to 70 Years · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Oct 1, 2026, 10:55 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Pulmonary Inflammation and Microbiome Changes With Bariatric Surgery in Obese Asthma

NCT04247971
View directory record Official record
Conditions
Asthma, Obesity
Interventions
Blood draw, Sputum collection, Pulmonary function test
Procedure
Lead sponsor
Duke University
Other
Eligibility
21 Years to 60 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 16, 2023 · Synced Oct 1, 2026, 10:55 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Path to Optimal Black Maternal Heart Health: Comparing Two CVD Risk Reduction Interventions (Change of HEART)

NCT05499507
View directory record Official record
Conditions
Pregnancy Related, Hypertension, Obesity, Racism
Interventions
COH+
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years and older · Female only
Enrollment
345 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 1, 2026, 10:55 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Enhancing Weight Loss Maintenance With GLP-1RA (BYDUREON™) in Adolescents With Severe Obesity

NCT02496611
View directory record Official record
Conditions
Severe Obesity
Interventions
Weight loss with pharmacotherapy, Weight loss without pharmacotherapy
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
12 Years to 17 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 3, 2022 · Synced Oct 1, 2026, 10:55 PM EDT
Completed Not applicable Interventional

A Virtual Reality Intervention to Improve Weight Maintenance

NCT01841372
View directory record Official record
Conditions
Weight Loss
Interventions
Second Life, Group Phone Conference Call
Other · Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Oct 1, 2026, 10:55 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Strength Training Exercise in Pediatric Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (STEP-ALL)

NCT07634653
View directory record Official record
Conditions
Leukemia, Acute Leukemia, Acute Lymphoid Leukemia, Lymphoblastic Lymphoma, Acute Lymphoblastic Leukemia
Interventions
Exercises
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
6 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 1, 2026, 10:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Promoting Employee Health Through The Worksite Food Environment

NCT02660086
View directory record Official record
Conditions
Weight, Food Choice, Nutrition Intake
Interventions
Personalized nutrition feedback
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 75 Years
Enrollment
602 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 1, 2021 · Synced Oct 1, 2026, 10:55 PM EDT
Completed Phase 4 Interventional Results available

Demonstrate the Effects of Pramlintide on Weight Reduction in Schizophrenia

NCT00690235
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Diabetes, Weight Gain
Interventions
Pramlintide, Placebo
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 16, 2018 · Synced Oct 1, 2026, 10:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Randomized Controlled Clinical Trial of Weight Loss Programs in Obese Persons

NCT00960414
View directory record Official record
Conditions
Obesity
Interventions
SHINE
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
194 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Oct 1, 2026, 10:55 PM EDT
Completed Not applicable Interventional

Postpartum Visit Timing and the Effect on Visit Attendance

NCT05399784
View directory record Official record
Conditions
Postpartum Disorder, Postpartum Depression, Postpartum Weight Retention, Breastfeeding, Satisfaction, Patient, Trust
Interventions
Early postpartum visit, Standard postpartum visit
Behavioral
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
13 Years to 50 Years · Female only
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 2, 2023 · Synced Oct 1, 2026, 10:55 PM EDT
Completed Not applicable Interventional

Flipped Classroom for Weight Management

NCT06622278
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Flipped Classroom
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Oct 1, 2026, 10:55 PM EDT
Completed Not applicable Interventional

Determinants of Fat Malabsorption After Roux-en-Y Gastric Bypass

NCT01252511
View directory record Official record
Conditions
Severe Obesity
Interventions
RYGB for surgical treatment of severe obesity
Procedure
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 17, 2019 · Synced Oct 1, 2026, 10:55 PM EDT
Not yet recruiting Not applicable Interventional

Endoscopic Sleeve Gastroplasty Technique Comparison for Weight Loss

NCT06299644
View directory record Official record
Conditions
Obesity, Obesity, Morbid, Metabolic Disease, Weight, Body
Interventions
Endoscopic Sleeve Gastroplasty - Belt and Suspenders, Endoscopic Sleeve Gastroplasty - Belt
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 1, 2026, 10:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Body Fat Reducing Effect and Safety of Enzymatically Modified Isoquercitrin in Overweight and Obese Subjects

NCT02818699
View directory record Official record
Conditions
Overweight, Obese
Interventions
Placebo, EMIQ
Dietary Supplement
Lead sponsor
Tufts University
Other
Eligibility
18 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 1, 2026, 10:55 PM EDT
Completed Phase 3 Interventional

Theory-Based Interventions for Smoking and Obesity (Challenge) Trial

NCT00040287
View directory record Official record
Conditions
Smoking, Obesity
Interventions
smoking cessation program, weight control program
Behavioral
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 60 Years
Enrollment
1,778 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1999
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 17, 2007 · Synced Oct 1, 2026, 10:55 PM EDT
Completed Not applicable Interventional

Weight Reduction Intervention for Breast Cancer Survivors

NCT00774371
View directory record Official record
Conditions
Breast Cancer
Interventions
Cognitive behavioral therapy CBT) for weight loss
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced Oct 1, 2026, 10:55 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Safety Study of the Inhibition of Agouti-related Protein (AgRP) for the Management of Obesity and Weight Loss

NCT00779519
View directory record Official record
Conditions
Obesity
Interventions
TTP435, Placebo
Drug
Lead sponsor
vTv Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2009
U.S. locations
9
States / cities
Los Angeles, California • San Diego, California • Augusta, Georgia + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 27, 2011 · Synced Oct 1, 2026, 10:55 PM EDT