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Showing 1–24 of 346 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Weight Gain Clear all
Completed Not applicable Interventional

Hearty Meals for Mom- Pilot Study of Meal Delivery for Cardiometabolic Health During Pregnancy

NCT05512247
View directory record Official record
Conditions
Diet, Healthy, Pregnancy
Interventions
Meal Delivery
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 5, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The WEIGH Study: Weighing to Improve and Gain Health

NCT01369004
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Daily Self-weighing + weekly feedback+ weekly lessons
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 60 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 24, 2017 · Synced Sep 5, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cardiovascular Health in Postpartum Women Diagnosed With Excessive Gestational Weight Gain

NCT02142452
View directory record Official record
Conditions
Pregnancy, Weight Gain
Interventions
behavioral intervention, Usual Prenatal Care
Behavioral · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 16, 2021 · Synced Sep 5, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CO-OP Trial: Community-based Outreach on Obesity in Pregnancy

NCT01841424
View directory record Official record
Conditions
Obesity, Pregnancy
Interventions
Dietary counseling. Maintain a food diary.
Behavioral
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
Female only
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
2
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 29, 2018 · Synced Sep 5, 2026, 5:55 AM EDT
Completed No phase listed Observational

Role Of Metabolic Adaptation In Weight Regain

NCT05766358
View directory record Official record
Conditions
Weight Loss, Weight Gain, Obesity
Interventions
Intensive lifestyle change therapy, Tirzepatide
Behavioral · Drug
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 9, 2024 · Synced Sep 5, 2026, 5:55 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

A Novel Obesity Prevention Program for High-Risk Infants in Primary Care

NCT06028113
View directory record Official record
Conditions
Obesity, Obesity, Childhood, Weight Gain, Weight Gain Trajectory
Interventions
THRIVE 2.0
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Day and older
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Sep 5, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Workplace-Sponsored Program to Reduce Obesity

NCT00123513
View directory record Official record
Conditions
Obesity, Cardiovascular Diseases
Interventions
Diet, Exercise, Environment
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
3,938 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 12, 2012 · Synced Sep 5, 2026, 5:55 AM EDT
Completed Phase 4 Interventional Results available

Topiramate vs. Placebo in Preventing Weight Gain in Bipolar Disorder Treated With Olanzapine

NCT00394095
View directory record Official record
Conditions
Bipolar Disorder, Weight Gain
Interventions
Topiramate, Placebo
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
10 Years to 18 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Sep 5, 2026, 5:55 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Menopausal Sleep Fragmentation and Body Fat Gain

NCT03047330
View directory record Official record
Conditions
Menopause
Interventions
Estradiol withdrawal, Fragmented sleep
Drug · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2024 · Synced Sep 5, 2026, 5:55 AM EDT
Completed Phase 3 Interventional

Behavioral Treatment of Weight Gain in CF

NCT00006169
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Behavioral Treatment
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
4 Years to 12 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 1999
U.S. locations
2
States / cities
Gainesville, Florida • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 1, 2010 · Synced Sep 5, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Fit Iterative App Development

NCT06148246
View directory record Official record
Conditions
Weight Gain Prevention, Physical Inactivity
Interventions
Family Fit Condition
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
9 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 5, 2026, 5:55 AM EDT
Recruiting Not applicable Interventional

Cessation of Dual Use of Cigarettes and E-cigarettes During Pregnancy

NCT07124702
View directory record Official record
Conditions
Dual Use of Cigarettes and E-cigarettes, Gestational Weight Gain, Birth-weight-for-gestational-age z Score
Interventions
Simultaneous cessation intervention, Stepwise cessation intervention, Behavior counseling only
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older · Female only
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Sep 5, 2026, 5:55 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Statewide (Rhode Island and Neighboring States) Partnerships for Worksite Weight Management

NCT00288145
View directory record Official record
Conditions
Overweight, Obesity
Interventions
WOW, Working On Wellness weight management
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
1,700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 30, 2013 · Synced Sep 5, 2026, 5:55 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effect of Dietary and Life Style Modification on Post Liver Transplant Obesity

NCT00878592
View directory record Official record
Conditions
Post Liver Transplantation Weight Gain, Post Liver Transplantation Obesity, Nonalcoholic Steatohepatitis
Interventions
Dietary and life style modification
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2008
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 9, 2017 · Synced Sep 5, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Magnesium Supplementation in the Second Trimester of Pregnancy to Overweight and Obese Individuals

NCT01510665
View directory record Official record
Conditions
Gestational Diabetes, Obesity
Interventions
Magnesium citrate, Placebo, Dietary modification
Dietary Supplement · Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
2
States / cities
Westwood, Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 13, 2013 · Synced Sep 5, 2026, 5:55 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks

NCT05674799
View directory record Official record
Conditions
Overweight or Obesity
Interventions
NDPP-NextGen
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 39 Years · Female only
Enrollment
403 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 5, 2026, 5:55 AM EDT
Recruiting Not applicable Interventional

Exercise Effects on Adipose Tissue Structure and Function

NCT04812314
View directory record Official record
Conditions
Obesity, Metabolic Syndrome, Metabolic Disease, Insulin Resistance, Weight Loss, Weight Gain
Interventions
Exercise, No exercise
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 40 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 5, 2026, 5:55 AM EDT
Completed No phase listed Observational

Assessing Virologic Success and Metabolic Changes in Patients Switching From a TDF to TAF Containing Antiretroviral Therapy Regimen

NCT03646370
View directory record Official record
Conditions
HIV-1-infection, Metabolic Syndrome, Cardiovascular Diseases, Weight Gain, Renal Function Abnormal, Hyperglycemia
Interventions
Tenofovir Alafenamide
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 22, 2019 · Synced Sep 5, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healthy Mom Zone: A Gestational Weight Gain Management Intervention

NCT03945266
View directory record Official record
Conditions
Overweight and Obesity, Physical Activity, Weight Change, Body, Eating Behavior
Interventions
Intervention group, Control group
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Sep 5, 2026, 5:55 AM EDT
Completed Not applicable Interventional Results available

Preventing Weight Gain and Unhealthy Behaviors in Children

NCT04608188
View directory record Official record
Conditions
Obesity
Interventions
Summer Camp
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
5 Years to 12 Years
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 18, 2024 · Synced Sep 5, 2026, 5:55 AM EDT
Completed Phase 2 Interventional Results available

Study to Evaluate ARD-101 in Adults Receiving Bariatric Surgery

NCT05215847
View directory record Official record
Conditions
Bariatric Surgery, Obesity, Weight Gain
Interventions
ARD-101
Drug
Lead sponsor
Aardvark Therapeutics, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Sep 5, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Targeting Pregnancy-related Weight Gain to Reduce Disparities in Obesity

NCT02229708
View directory record Official record
Conditions
Pregnancy, Body Weight Changes, Behavioral, Obesity
Interventions
Healthy Lifestyle Group
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years and older · Female only
Enrollment
262 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 16, 2019 · Synced Sep 5, 2026, 5:55 AM EDT
Recruiting Phase 3 Interventional

A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)

NCT06439277
View directory record Official record
Conditions
Obesity, Weight Gain
Interventions
Tirzepatide, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
12 Years to 17 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
14
States / cities
Los Angeles, California • Sacramento, California • Wilmington, Delaware + 11 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 5, 2026, 5:55 AM EDT
Completed No phase listed Observational

Energy Balance and Weight Gain With Ivacaftor Treatment

NCT02141464
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Not listed
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
6 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 18, 2017 · Synced Sep 5, 2026, 5:55 AM EDT