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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Weight Gain Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Preventing Excessive Weight Gain and Maternal and Infant Fat Accretion

NCT04868110
View directory record Official record
Conditions
Gestational Weight Gain, Maternal Fat Accretion, Infant Fat Accretion
Interventions
High fiber diet
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 26, 2025 · Synced Jul 22, 2026, 4:00 PM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers

Adjunctive Supplementation of Antioxidants (Vitamins E + C) Plus Omega-3 Fatty Acids

NCT00211562
View directory record Official record
Conditions
Schizophrenia
Interventions
Olanzapine, Omega 3, Vitamin E+C
Drug
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2005
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 23, 2012 · Synced Jul 22, 2026, 4:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Workplace-Sponsored Program to Reduce Obesity

NCT00123513
View directory record Official record
Conditions
Obesity, Cardiovascular Diseases
Interventions
Diet, Exercise, Environment
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
3,938 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 12, 2012 · Synced Jul 22, 2026, 4:00 PM EDT
Completed Phase 4 Interventional

Zonegran for the Treatment of Weight Gain Associated With Psychotropic Medication Use: A Placebo-Controlled Trial

NCT00203450
View directory record Official record
Conditions
Obesity
Interventions
Zonegran, Placebo
Drug
Lead sponsor
Tuscaloosa Research & Education Advancement Corporation
Other
Eligibility
19 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 2, 2012 · Synced Jul 22, 2026, 4:00 PM EDT
Completed Phase 4 Interventional Results available

Demonstrate the Effects of Pramlintide on Weight Reduction in Schizophrenia

NCT00690235
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Diabetes, Weight Gain
Interventions
Pramlintide, Placebo
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 15, 2018 · Synced Jul 22, 2026, 4:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Balance: A Pragmatic Trial of a Digital Health Intervention to Prevent Weight Gain in Primary Care

NCT03003403
View directory record Official record
Conditions
Obesity, Overweight, Overnutrition, Nutrition Disorders, Signs and Symptoms
Interventions
Intervention Program
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years and older
Enrollment
443 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Jul 22, 2026, 4:00 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Determinants of Gestational Weight Gain in Obese Pregnant Women

NCT01954342
View directory record Official record
Conditions
Energy Intake, Energy Expenditure
Interventions
Not listed
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 15, 2021 · Synced Jul 22, 2026, 4:00 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Project Sueño: Sleep & Understanding Early Nutrition in Obesity

NCT06117631
View directory record Official record
Conditions
Infant Overweight, Infant Obesity, Infant Overnutrition, Infant Development, Metabolic Syndrome, Diabetes Mellitus Risk
Interventions
Centering Parenting, Bright by Text
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
256 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Jul 22, 2026, 4:00 PM EDT
Completed Phase 2 Interventional Results available

Efficacy and Tolerability Study of Betahistine to Ameliorate Antipsychotic Associated Weight Gain

NCT00709202
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Bipolar I Disorder, Bipolar II, Bipolar NOS(Not Otherwise Specified), Psychotic Disorder Not Otherwise Specified, Autism Spectrum Disorder
Interventions
Betahistine, Placebo Oral Tablet
Drug
Lead sponsor
Nathan Kline Institute for Psychiatric Research
Other
Eligibility
18 Years to 59 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Orangeburg, New York
Source: ClinicalTrials.gov public record
Updated Jan 24, 2019 · Synced Jul 22, 2026, 4:00 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Reducing Binge Eating to Prevent Weight Gain in Black Women

NCT03531112
View directory record Official record
Conditions
Binge Eating, Weight Loss, Weight Gain Prevention
Interventions
Appetite Awareness Treatment + Lifestyle Modification
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 16, 2021 · Synced Jul 22, 2026, 4:00 PM EDT
Completed Phase 3 Interventional

Behavioral Treatment of Weight Gain in CF

NCT00006169
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Behavioral Treatment
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
4 Years to 12 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 1999
U.S. locations
2
States / cities
Gainesville, Florida • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 1, 2010 · Synced Jul 22, 2026, 4:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Denver Garden Environment and Microbiome Study Disease

NCT03089151
View directory record Official record
Conditions
Diet Modification, Physical Activity, Weight Gain, Chronic Disease, Lifestyle, Sedentary, Health Behavior
Interventions
Community Garden Intervention
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated May 6, 2021 · Synced Jul 22, 2026, 4:00 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Blossom Project: "BlossomUP" Methods to Decrease Sedentary Time in Pregnancy

NCT02909725
View directory record Official record
Conditions
Sedentary Lifestyle, Diabetes Mellitus, Gestational
Interventions
Limit accumulation of sedentary time, Walk, Normal daily routine; Usual Care
Other
Lead sponsor
Iowa State University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Ames, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 20, 2016 · Synced Jul 22, 2026, 4:00 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Delivering HOPE (Helping Women Optimize Prenatal Equity)

NCT06814509
View directory record Official record
Conditions
Gestational Weight Gain, Diet, Healthy, Gestational Hypertension, Gestational Diabetes, Pregnancy Complications
Interventions
Enhanced Standard of Care (ESoC), Delivering HOPE
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
16 Years to 44 Years · Female only
Enrollment
1,440 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
8
States / cities
Corning, Arkansas • Lavaca, Arkansas • Marianna, Arkansas + 5 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Jul 22, 2026, 4:00 PM EDT
Completed Early Phase 1 Interventional

Nutrition and Physical Activity Intervention in Preventing Excess Weight Gain in Pediatric Patients With Leukemia or Lymphoma Treated With Prednisone and/or Dexamethasone

NCT05049785
View directory record Official record
Conditions
Leukemia, Lymphoma
Interventions
Counseling, Exercise Intervention, Informational Intervention, Nutritional Intervention, Questionnaire Administration
Other · Behavioral · Dietary Supplement
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
7 Years to 18 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Jul 22, 2026, 4:00 PM EDT
Completed Not applicable Interventional

Development of Fluid Intake App for Management of Fluid Intake During Hemodialysis

NCT03759847
View directory record Official record
Conditions
Weight Gain
Interventions
Fluid intake app, Survey
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 8, 2024 · Synced Jul 22, 2026, 4:00 PM EDT
Terminated Not applicable Interventional

Pilot Study of Dietary Modification of Appetite Set Point in Obesity

NCT00726271
View directory record Official record
Conditions
Obesity
Interventions
light olive oil, fish oil capsules, flax seed oil capsules
Dietary Supplement
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2021 · Synced Jul 22, 2026, 4:00 PM EDT
Completed Not applicable Interventional

Testing the Influence of Different Sugary Drink Warning Label Designs

NCT03648138
View directory record Official record
Conditions
Obesity, Weight Gain, Diabetes Type 2
Interventions
Sugary drink warning labels
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
1,016 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 10, 2020 · Synced Jul 22, 2026, 4:00 PM EDT
Completed Not applicable Interventional

Impact of a Personal Digital Assistant (PDA) - Based Dietary Adherence Intervention on Interdialytic Weight Gain and Blood Pressure in Hemodialysis Patients

NCT00447408
View directory record Official record
Conditions
End-Stage Renal Disease
Interventions
Standard hemodialysis dietary instruction, Behavioral counseling plus PDA-based self-monitoring of diet
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 27, 2010 · Synced Jul 22, 2026, 4:00 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Daily Step Count and Achieving Goal Gestational Weight Gain

NCT04605406
View directory record Official record
Conditions
Pregnancy Related
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 13, 2023 · Synced Jul 22, 2026, 4:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prevention of Weight Gain

NCT00011102
View directory record Official record
Conditions
Obesity, Body Weight Changes
Interventions
Weight Gain Prevention for Women Project
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
25 Years to 44 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2001
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 13, 2010 · Synced Jul 22, 2026, 4:00 PM EDT
Completed No phase listed Observational

Body Heat Content and Dissipation in Obese and Normal Weight Adults

NCT00266500
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Jul 22, 2026, 4:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Teaching Appropriate Gestational Weight Gain

NCT02963428
View directory record Official record
Conditions
Obesity
Interventions
Enhanced Care
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
Female only
Enrollment
218 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 13, 2019 · Synced Jul 22, 2026, 4:00 PM EDT
Completed Phase 4 Interventional Results available

The Use of Metformin in the Treatment of Antipsychotic-Induced Weight Gain in Schizophrenia (The METS Study)

NCT00816907
View directory record Official record
Conditions
Schizophrenia
Interventions
Metformin, Placebo
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 65 Years
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
16
States / cities
Palo Alto, California • Boca Raton, Florida • Iowa City, Iowa + 13 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2013 · Synced Jul 22, 2026, 4:00 PM EDT