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Showing 1–24 of 63 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Weight Gain Prevention Clear all
Completed Phase 2 Interventional Accepts healthy volunteers

Exenatide for Smoking Cessation and Prevention of Weight Gain

NCT05610800
View directory record Official record
Conditions
Smoking Cessation, Weight Gain
Interventions
Exenatide 2 milligram (mg) Injection, Placebo, Nicotine patch, Smoking Cessation Counseling
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Sep 15, 2026, 1:02 PM EDT
Completed Phase 2 Interventional

Preventing Excessive Weight Gain in Adolescent Girls at High-Risk for Adult Obesity

NCT00680979
View directory record Official record
Conditions
Obesity, Overweight, Binge Eating
Interventions
Interpersonal Psychotherapy, Health Education
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
12 Years to 17 Years · Female only
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
2
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 30, 2019 · Synced Sep 15, 2026, 1:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparative Effectiveness of Adding Weight Control to Smoking Cessation Quitlines

NCT01867983
View directory record Official record
Conditions
Cigarette Smoking, Overweight, Obesity
Interventions
Weight gain prevention and smoking cessation, Smoking cessation
Behavioral
Lead sponsor
Consumer Wellness Solutions
Industry
Eligibility
18 Years and older
Enrollment
2,540 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 14, 2016 · Synced Sep 15, 2026, 1:02 PM EDT
Completed Phase 3 Interventional Results available

Assessment of Safety and Efficacy of Therapy for the Prevention of Weight Gain Associated With Olanzapine

NCT00401973
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorders
Interventions
olanzapine, amantadine, metformin, zonisamide, Wellness education
Drug · Behavioral
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 65 Years
Enrollment
199 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
5
States / cities
National City, California • Canton, Ohio • Johnson City, Tennessee + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2009 · Synced Sep 15, 2026, 1:02 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Prevention of Weight Gain in Adult Patients With Type 2 Diabetes Treated With Pioglitazone

NCT00737347
View directory record Official record
Conditions
Type 2 Diabetes, Obesity
Interventions
Lifestyle modification
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
21 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 18, 2008 · Synced Sep 15, 2026, 1:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pregnancy Weight Tracking Pilot Project

NCT03652766
View directory record Official record
Conditions
Obesity Complicating Childbirth
Interventions
Daily Weight Tracking
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 29, 2020 · Synced Sep 15, 2026, 1:02 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Reducing Binge Eating to Prevent Weight Gain in Black Women

NCT03531112
View directory record Official record
Conditions
Binge Eating, Weight Loss, Weight Gain Prevention
Interventions
Appetite Awareness Treatment + Lifestyle Modification
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 16, 2021 · Synced Sep 15, 2026, 1:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Appetite Regulation in Patients With Obesity

NCT05200520
View directory record Official record
Conditions
Weight Loss, Weight Gain Prevention, Obesity
Interventions
Appetite Self-Regulation Intervention
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 8, 2023 · Synced Sep 15, 2026, 1:02 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

The SLeeping and Intake Methods Taught to Infants and Mothers Early in Life (SLIMTIME) Project

NCT00359242
View directory record Official record
Conditions
Weight Gain, Obesity
Interventions
Infant Sleeping and Soothing, Repeated Food Exposure
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
1 Day to 12 Months
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 27, 2017 · Synced Sep 15, 2026, 1:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Fit Iterative App Development

NCT06148246
View directory record Official record
Conditions
Weight Gain Prevention, Physical Inactivity
Interventions
Family Fit Condition
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
9 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 15, 2026, 1:02 PM EDT
Terminated Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Addressing Post Cessation Weight Gain

NCT02412631
View directory record Official record
Conditions
Obesity, Smoking Cessation
Interventions
lorcaserin, Varenicline, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 9, 2021 · Synced Sep 15, 2026, 1:02 PM EDT
Recruiting Not applicable Interventional

Brief Behavioral Sleep Intervention for Obesity Prevention in Primary Care

NCT06810557
View directory record Official record
Conditions
Obesity, Childhood, Short Sleep, Obesity Prevention
Interventions
Optimize Sleep Primary Care (OSPC), Enhanced Usual Care
Behavioral · Other
Lead sponsor
Temple University
Other
Eligibility
6 Years to 11 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Sep 15, 2026, 1:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Environmental Intervention for Weight Gain Prevention

NCT00708461
View directory record Official record
Conditions
Obesity
Interventions
weight gain prevention
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 70 Years
Enrollment
1,747 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Sep 15, 2026, 1:02 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Statewide (Rhode Island and Neighboring States) Partnerships for Worksite Weight Management

NCT00288145
View directory record Official record
Conditions
Overweight, Obesity
Interventions
WOW, Working On Wellness weight management
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
1,700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 30, 2013 · Synced Sep 15, 2026, 1:02 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Binge Eating Self-help Treatment for University Students

NCT01888406
View directory record Official record
Conditions
Obesity, Binge Eating Disorder
Interventions
Guided Self-Help, Pure Self-Help
Behavioral
Lead sponsor
Francine Rosselli
Other
Eligibility
18 Years to 22 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
2
States / cities
Manchester, Connecticut • Middletown, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 26, 2013 · Synced Sep 15, 2026, 1:02 PM EDT
Completed Not applicable Interventional

Behavior Change Family Counseling to Reduce Rate of Weight Gain in At-Risk Children

NCT00241891
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Obesity
Interventions
Single behavior intervention, Multiple behavior interventions, Control Intervention unrelated to weight
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years to 12 Years
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 6, 2015 · Synced Sep 15, 2026, 1:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Cafeteria Based Study of Weight Gain Prevention

NCT00573482
View directory record Official record
Conditions
Obesity, Overweight
Interventions
REDE, control
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
21 Years to 65 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 24, 2010 · Synced Sep 15, 2026, 1:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Program for Weight Gain Prevention

NCT00989170
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Family Program for the Prevention of Weight Gain, Control Group
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
3 Years to 65 Years
Enrollment
418 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 9, 2016 · Synced Sep 15, 2026, 1:02 PM EDT
Terminated Phase 2 Interventional

Olanzapine Given in Combination With Zonisamide SR to Prevent Weight Gain in Schizophrenic Subjects

NCT00734435
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder
Interventions
zonisamide SR plus olanzapine, Placebo plus olanzapine
Drug
Lead sponsor
Orexigen Therapeutics, Inc
Industry
Eligibility
18 Years to 55 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
9
States / cities
National City, California • Orange, California • San Diego, California + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 28, 2012 · Synced Sep 15, 2026, 1:02 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Preventing Obesity in Military Communities: Mother-Baby

NCT03249324
View directory record Official record
Conditions
Pregnancy, Overweight, Obesity
Interventions
Positive-Gain Counseling (PGC), Usual Care
Behavioral · Other
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Marine Corps Base Camp Lejeune, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 14, 2017 · Synced Sep 15, 2026, 1:02 PM EDT
Not listed Not applicable Interventional

Weight Gain Prevention for Breast Cancer Survivors

NCT00533338
View directory record Official record
Conditions
Breast Cancer
Interventions
Weight Gain Prevention Program, Questionnaire
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 12, 2020 · Synced Sep 15, 2026, 1:02 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

School Worksite Weight Gain Prevention Intervention Study

NCT01467284
View directory record Official record
Conditions
Obesity
Interventions
Step Ahead, Basic Intervention
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
Not listed
Enrollment
844 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 17, 2014 · Synced Sep 15, 2026, 1:02 PM EDT
Completed Not applicable Interventional

The Use of Smart Scales for Weight Gain Prevention in African American Breast Cancer Survivors

NCT02030353
View directory record Official record
Conditions
Body Weight Changes, Breast Neoplasms
Interventions
Self-regulation plus activity monitoring, Self-regulation
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 19, 2016 · Synced Sep 15, 2026, 1:02 PM EDT
Completed Not applicable Interventional

Healthy Homes/Healthy Kids Preschool

NCT01080885
View directory record Official record
Conditions
Obesity
Interventions
Busy Bodies/Better Bites, Healthy Spots/Safe Tots
Behavioral
Lead sponsor
HealthPartners Institute
Other
Eligibility
2 Years to 4 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 22, 2012 · Synced Sep 15, 2026, 1:02 PM EDT