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ClinicalTrials.gov public records Last synced Oct 20, 2026, 7:28 AM EDT

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Showing 385–408 of 1,735 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Weight Loss Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Commercial Program on Weight Loss and Health Outcomes 2

NCT03079128
View directory record Official record
Conditions
Weight Loss
Interventions
Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 75 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Oct 20, 2026, 7:28 AM EDT
Completed Not applicable Interventional

Spark: Finding the Optimal Tracking Strategy for Weight Loss in a Digital Health Intervention

NCT05249465
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss, Health Behavior
Interventions
Core behavioral weight loss intervention, Self-monitoring diet, Self-monitoring weight, Self-monitoring steps
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2025 · Synced Oct 20, 2026, 7:28 AM EDT
Completed Not applicable Interventional Results available

OA Clinic-Community CARE Model

NCT05349500
View directory record Official record
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip, Overweight, Obesity, Physical Inactivity, Weight Loss
Interventions
OA CARE Intervention, Usual Care control group
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Oct 20, 2026, 7:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Partners in Health: A Couples-based Approach to Obesity Prevention

NCT02205281
View directory record Official record
Conditions
Obesity
Interventions
Lifestyle Intervention
Behavioral
Lead sponsor
California Polytechnic State University-San Luis Obispo
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
San Luis Obispo, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2020 · Synced Oct 20, 2026, 7:28 AM EDT
Completed Not applicable Interventional

Progressive Weight Loss and Metabolic Health

NCT01299519
View directory record Official record
Conditions
Insulin Resistance, Obesity
Interventions
Weight Maintenance, Weight Loss
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
21 Years to 65 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 5, 2017 · Synced Oct 20, 2026, 7:28 AM EDT
Completed Not applicable Interventional Results available

Healthy Lifestyles for Mentally Ill People Who Have Experienced Weight Gain From Their Antipsychotic Medications

NCT00344500
View directory record Official record
Conditions
Diabetes, Obesity, Weight Gain
Interventions
Behavioral Weight Loss Program
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 6, 2016 · Synced Oct 20, 2026, 7:28 AM EDT
Completed Not applicable Interventional

Effects of Diet and Exercise on Ductal Carcinoma in Situ

NCT02224807
View directory record Official record
Conditions
Ductal Carcinoma In Situ, Breast Cancer
Interventions
Active Comparator: Progressive Resistance Training (PRT) and a healthy diet, Experimental: PRT and a healthy diet, plus weight loss
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 31, 2018 · Synced Oct 20, 2026, 7:28 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Engaging Men in Weight Loss With a Game-based mHealth and Neurotraining Program

NCT05408494
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Gamified behavioral weight loss treatment, mHealth behavioral weight loss treatment
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 65 Years
Enrollment
228 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Oct 20, 2026, 7:28 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Safety and Efficacy of APD356 in the Treatment of Obesity

NCT00116740
View directory record Official record
Conditions
Obesity
Interventions
APD356
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 12, 2019 · Synced Oct 20, 2026, 7:28 AM EDT
Recruiting Phase 2 Interventional

Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer

NCT06518837
View directory record Official record
Conditions
Hormone Receptor-Positive Breast Cancer, HER2-Negative Breast Cancer
Interventions
Tirzepatide
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
7
States / cities
Elizabeth, New Jersey • Hamilton, New Jersey • Livingston, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 20, 2026, 7:28 AM EDT
Not yet recruiting Phase 3 Interventional

SYNCHRONIZE®-START- A Study to Test Whether Survodutide Helps People Living With Overweight or Obesity Who do Not Have Diabetes to Lose Weight

NCT07855900
View directory record Official record
Conditions
Obesity
Interventions
Survodutide
Combination Product
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Riverview, Florida
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 20, 2026, 7:28 AM EDT
Completed Phase 4 Interventional Results available

Intervention to Promote Weight Loss in Latinas At-risk for Diabetes

NCT02088034
View directory record Official record
Conditions
Diabetes
Interventions
Promotora-led Intervention, Metformin Therapy, Usual Care
Behavioral · Drug · Other
Lead sponsor
Temple University
Other
Eligibility
20 Years to 75 Years · Female only
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 22, 2020 · Synced Oct 20, 2026, 7:28 AM EDT
Completed Not applicable Interventional

MPOWERed Messages: Tailored Mobile Messages to Enhance Weight Loss for Teens

NCT01448551
View directory record Official record
Conditions
Obesity
Interventions
Tailored Mobile Messages to Enhance Weight Loss for Teens
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
12 Years to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 21, 2016 · Synced Oct 20, 2026, 7:28 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

LEAN Project: Weight Loss and Appetite Suppression

NCT00153790
View directory record Official record
Conditions
Weight Loss
Interventions
PhosphoLean
Drug
Lead sponsor
The Cooper Institute
Other
Eligibility
30 Years to 45 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 13, 2014 · Synced Oct 20, 2026, 7:28 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Effect of Revival Soy on Weight Loss and Skin, Hair, and Nails in Premenopausal Women

NCT00352157
View directory record Official record
Conditions
Skin Aging, Weight Loss
Interventions
Revival Soy Dietary Supplement
Behavioral
Lead sponsor
Physicians Pharmaceuticals, Inc.
Industry
Eligibility
25 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
High Point, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 21, 2009 · Synced Oct 20, 2026, 7:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Weight Loss on Myocardial Metabolism and Cardiac Relaxation in Obese Adults

NCT00572624
View directory record Official record
Conditions
Obesity
Interventions
Diet, Gastric bypass surgery
Behavioral · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
21 Years to 50 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 15, 2017 · Synced Oct 20, 2026, 7:28 AM EDT
Not listed Phase 4 Interventional

Lorcaserin for Weight Loss Management in Patients on Antipsychotics: A Pilot Study

NCT01962402
View directory record Official record
Conditions
Weight Gain
Interventions
lorcaserin, Intensive dietary counseling
Drug · Behavioral
Lead sponsor
Southern California Institute for Research and Education
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2014
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Jan 30, 2014 · Synced Oct 20, 2026, 7:28 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Bioenergetic Alterations After Exenatide Administration

NCT00623545
View directory record Official record
Conditions
Healthy
Interventions
Exenatide
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 9, 2015 · Synced Oct 20, 2026, 7:28 AM EDT
Completed Phase 3 Interventional

Methods of Weight Loss in Overweight Coronary Patients

NCT00628277
View directory record Official record
Conditions
Obesity
Interventions
high caloric expenditure exercise, low caloric expenditure exercise plus dietary counseling
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
21 Years to 90 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Mar 5, 2008 · Synced Oct 20, 2026, 7:28 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Choose to Lose for Women-Weight Loss to Reduce Breast Cancer Risk Factors

NCT01096901
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Behavioral Weight loss
Behavioral
Lead sponsor
California Polytechnic State University-San Luis Obispo
Other
Eligibility
30 Years to 45 Years · Female only
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
San Luis Obispo, California
Source: ClinicalTrials.gov public record
Updated Oct 28, 2015 · Synced Oct 20, 2026, 7:28 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)

NCT07083557
View directory record Official record
Conditions
Obesity and Obesity-related Medical Conditions, Diabetes, Atherosclerotic Disease, Heart Failure, MASH, Sarcopenia, Osteoporosis, Hyperparathyroidism, Hypoparathyroidism, Ischemic Heart Disease, Cystic Fibrosis (CF), Chronic Kidney Disease(CKD), Osteopenia, Cachexia
Interventions
Endothelial cell collection
Other
Lead sponsor
Bettina Mittendorfer
Other
Eligibility
18 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2030
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 20, 2026, 7:28 AM EDT
Completed Not applicable Interventional

Efficacy of Serum Bovine Immunoglobulin in Improving Nutritional Status in Advanced COPD

NCT02067377
View directory record Official record
Conditions
Advanced COPD (GOLD Stage 3 or 4) With Cachexia
Interventions
Serum bovine immunoglobulin (SBI) medical food, Placebo (for serum bovine immunoglobulin)
Dietary Supplement
Lead sponsor
Medical University of South Carolina
Other
Eligibility
30 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 2, 2016 · Synced Oct 20, 2026, 7:28 AM EDT
Enrolling by invitation Phase 2 Interventional

Comparing Olanzapine and Mirtazapine in the Improvement of Unintentional Weight Loss for Patients with Advanced Stage Cancer

NCT05170919
View directory record Official record
Conditions
Anorexia Nervosa with Significantly Low Body Weight
Interventions
Mirtazapine, Olanzapine
Drug
Lead sponsor
Englewood Hospital and Medical Center
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Englewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 20, 2026, 7:28 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Outcomes After Weight Loss Surgery in Low-Risk Patients

NCT05699083
View directory record Official record
Conditions
Weight Loss, Bariatric Surgery
Interventions
Body Image/Self-Esteem Questionnaires
Other
Lead sponsor
Dr. Feiz & Associates
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Beverly Hills, California
Source: ClinicalTrials.gov public record
Updated Jan 26, 2023 · Synced Oct 20, 2026, 7:28 AM EDT