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ClinicalTrials.gov public records Last synced Oct 21, 2026, 6:21 PM EDT

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Showing 625–648 of 1,735 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Weight Loss Clear all
Completed Phase 2Phase 3 Interventional Results available

Pharmacological and Behavioral Treatment After Bariatric Surgery: Medication Change for Non-Responders (Stage 2b)

NCT04599504
View directory record Official record
Conditions
Loss-of-control Eating, Obesity/Overweight
Interventions
Lisdexamfetamine Dimesylate (Medication), Placebo
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 64 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Safety and Efficacy of APD356 in the Treatment of Obesity

NCT00104507
View directory record Official record
Conditions
Obesity
Interventions
APD356
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 12, 2019 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Heart-Healthy Lenoir Lifestyle Study

NCT01433484
View directory record Official record
Conditions
Cardiovascular Disease, Obesity
Interventions
Maintenance of Weight Loss--Control, Maintenance of Weight Loss--Experimental
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
339 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Kinston, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 20, 2017 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Neurocognitive Benefits of a Weight Management Program

NCT04202133
View directory record Official record
Conditions
Overweight and Obesity
Interventions
WW (formerly Weight Watchers), Waitlist
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Oct 21, 2026, 6:21 PM EDT
Enrolling by invitation No phase listed Observational

Linking Temporal Patterns of Modifiable Behaviors to Weight Loss Outcomes

NCT03840733
View directory record Official record
Conditions
Obesity, Weight Change, Body
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

DAMES: Daughters And MothErS Against Breast Cancer

NCT00630591
View directory record Official record
Conditions
Breast Cancer
Interventions
Standardized Materials Group, Independent Tailored Intervention, Partner-Assisted Tailored Intervention
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years and older · Female only
Enrollment
482 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
2
States / cities
Durham, North Carolina • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 2, 2017 · Synced Oct 21, 2026, 6:21 PM EDT
Enrolling by invitation Not applicable Interventional

Testing a Multilevel, Culturally Appropriate Lifestyle Intervention For Hispanic Patients With Metabolic Dysfunction-associated Steatotic Liver Disease

NCT07199491
View directory record Official record
Conditions
Metabolic-dysfunction Associated Liver Disease (MASLD)
Interventions
Healthy Liver/Hígado Sano program, Usual Care
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 21, 2026, 6:21 PM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Lorcaserin in Obesity: Identification of CNS Targets Using fMRI

NCT02400359
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Lorcaserin HCl, Placebo
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Not applicable Interventional Results available

Ignite Pilot: Goal Setting in a Digital Weight Loss Intervention

NCT05715242
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss, Health Behavior
Interventions
Core Behavioral Weight Loss Intervention, Easier Step Goal, Harder Step Goal, Easier Calorie Goal, Harder Calorie Goal, Easier Eating Window Goal, Harder Eating Window Goal, Easier Red Zone Food Goal, Harder Red Zone Food Goal
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Esophageal Cytology With FISH in Detecting Esophageal Cancer

NCT02100189
View directory record Official record
Conditions
Dysphagia, Dysplasia, Esophageal Adenocarcinoma, Esophageal Squamous Cell Carcinoma, Esophagitis, Gastroesophageal Reflux Disease, High Grade Dysplasia in Barrett Esophagus, Weight Loss
Interventions
Cytology Specimen Collection Procedure, Esophagogastroduodenoscopy, Laboratory Biomarker Analysis
Other · Procedure
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 11, 2017 · Synced Oct 21, 2026, 6:21 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Study to Determine the Feasibility of Online Recruitment of People Using an Anti-Obesity Medication for Weight Loss

NCT06761703
View directory record Official record
Conditions
Obesity
Interventions
TAP® Micro Select Device (Touch Activated Phlebotomy)
Device
Lead sponsor
Amgen
Industry
Eligibility
18 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Medford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Oct 21, 2026, 6:21 PM EDT
Not listed Phase 3 Interventional

A Weight-Loss Program in Helping Obese Black Women Lose Weight

NCT00859989
View directory record Official record
Conditions
Breast Cancer, Obesity, Weight Changes
Interventions
behavioral dietary intervention, exercise intervention, telephone-based intervention, counseling intervention, educational intervention, immunoenzyme technique, laboratory biomarker analysis, questionnaire administration, study of socioeconomic and demographic variables, evaluation of cancer risk factors, support group therapy
Behavioral · Other · Procedure
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
30 Years to 50 Years · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 18, 2013 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Benzoates - an Obesogenic Endocrine Disrupting Chemical

NCT03190785
View directory record Official record
Conditions
Obesity, Metabolic Syndrome
Interventions
Benzoic acid washout and exposure
Other
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 30 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 24, 2023 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Energy Balance Weight Regulation Study

NCT00619008
View directory record Official record
Conditions
Obesity
Interventions
Ad libitum low carbohydrate diet, Ad libitum High Complex Carbohydrate Diet, Energy-restricted high complex carbohydrate diet
Other
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
21 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 3, 2008 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Phase 3 Interventional

A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose Weight

NCT06388187
View directory record Official record
Conditions
Obesity
Interventions
Cagrilintide, Semaglutide, Placebo
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
7
States / cities
Costa Mesa, California • Plantation, Florida • Indianapolis, Indiana + 4 more
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diet Induced Weight Loss to Reduce Inflammation in Obese Women

NCT01699906
View directory record Official record
Conditions
Obesity
Interventions
Diet regimen to induce weight loss
Other
Lead sponsor
Rockefeller University
Other
Eligibility
40 Years to 70 Years · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 5, 2014 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Not applicable Interventional

A Remote Delivered Lifestyle Therapeutics Program

NCT04201028
View directory record Official record
Conditions
Body Weight Changes, Weight Loss, Healthy Diet, Obesity
Interventions
Video Conferencing Health Coaching with devices, Video Conferencing Health Coaching with no devices
Behavioral
Lead sponsor
Coastal Carolina University
Other
Eligibility
20 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Oct 6, 2022 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Healthy Bodies, Healthy Hearts: A Physical Activity Intervention Trial

NCT01099007
View directory record Official record
Conditions
Obesity, Cardiovascular Disease, High Blood Pressure
Interventions
In Person, At Home
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 22, 2014 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Prevent in Underserved Populations

NCT02664064
View directory record Official record
Conditions
Prediabetes, Overweight, Obesity
Interventions
Prevent
Behavioral
Lead sponsor
Omada Health, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
227 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
3
States / cities
Los Angeles, California • San Fernando, California • Monroe, Washington
Source: ClinicalTrials.gov public record
Updated Mar 4, 2020 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Phase 2 Interventional

Study To Determine The Effects And Safety Of A Weight Loss Compound On Overweight, Otherwise Healthy, Volunteers

NCT00479492
View directory record Official record
Conditions
Obesity
Interventions
CP-866,087, placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 65 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
4
States / cities
Orlando, Florida • Kalamazoo, Michigan • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2009 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lose Now North Carolina Community Weight Loss Program

NCT01615471
View directory record Official record
Conditions
Obesity
Interventions
Group weight loss with companion internet
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
195 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 24, 2017 · Synced Oct 21, 2026, 6:21 PM EDT
Terminated Phase 2 Interventional Results available

The Effect of Surgically Induced Weight Loss on Endocrine Function, Cardiovascular Function and Body Composition

NCT00686972
View directory record Official record
Conditions
Bariatric Surgery
Interventions
GLP-1
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 65 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Promoting Healthy Weight With 'Stability Skills First'

NCT00626457
View directory record Official record
Conditions
Obesity
Interventions
Behavioral weight-loss/lifestyle interventions
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
21 Years and older · Female only
Enrollment
267 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
2
States / cities
Stanford, California • Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 1, 2015 · Synced Oct 21, 2026, 6:21 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Cannabis for Obesity Trial

NCT06137365
View directory record Official record
Conditions
Obesity
Interventions
Cannabis, Placebo
Drug
Lead sponsor
Joshua A. Lile, Ph.D.
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 21, 2026, 6:21 PM EDT