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ClinicalTrials.gov public records Last synced Oct 18, 2026, 9:12 PM EDT

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Showing 217–240 of 257 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Weight Loss Trial Clear all
Completed Not applicable Interventional

A Weight Loss Trial for Emotional Eating

NCT02055391
View directory record Official record
Conditions
Obesity
Interventions
Behavioral Weight Loss, Enhanced Behavioral Weight Loss
Behavioral
Lead sponsor
Temple University
Other
Eligibility
21 Years to 65 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 5, 2014 · Synced Oct 18, 2026, 9:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Bite Counter for Weight Loss: A One-month Usability Trial to Test the Effectiveness of Using the Bite Counter

NCT02494674
View directory record Official record
Conditions
Obesity
Interventions
Bite Counter tracking
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Oct 18, 2026, 9:12 PM EDT
Enrolling by invitation Not applicable Interventional

To Test the Effectiveness and Implementation Approach of a 3-month PILI Pasifika Program Lifestyle Program With Components of Social Determinants of Health Activities in Real-world Settings (Clinical and Non-clinical Settings) Across 3 Years

NCT07387393
View directory record Official record
Conditions
Cardiometabolic Conditions, Hypertension (HTN), Dyslipidemia, Pre-diabetes, Type 2 Diabetes Mellitus (T2DM), Overweight (BMI > 25), Weight Loss Trial
Interventions
PILI (Partnership for Improving Lifestyle Intervention) Pasifika Program
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Fayetteville, Arkansas • Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 18, 2026, 9:12 PM EDT
Completed Not applicable Interventional Results available

DVD Lifestyle Intervention

NCT03260140
View directory record Official record
Conditions
Obesity
Interventions
behavioral lifestyle intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
511 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 28, 2023 · Synced Oct 18, 2026, 9:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Adaptive Physical Activity Intervention for Overweight Adults

NCT01793064
View directory record Official record
Conditions
Physical Activity
Interventions
Adaptive Intervention (AI), Static Intervention (SI)
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 15, 2014 · Synced Oct 18, 2026, 9:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Single Arm Trial of a Multi-component Commercial Digital Weight Loss Program

NCT04302389
View directory record Official record
Conditions
Weight Loss
Interventions
myWW App, Virtual Workshops, and Private Facebook Group
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 75 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Oct 18, 2026, 9:12 PM EDT
Recruiting Phase 2 Interventional

Atomoxetine in Melanocortin Obesity Syndrome

NCT06899178
View directory record Official record
Conditions
Melanocortin Obesity Syndrome, MCOS
Interventions
Atomoxetine, Placebo
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
6 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
3
States / cities
New York, New York • Columbus, Ohio • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 18, 2026, 9:12 PM EDT
Completed Not applicable Interventional Results available

Promoting Successful Weight Loss in Primary Care in Louisiana

NCT02561221
View directory record Official record
Conditions
Obesity
Interventions
Lifestyle Counseling
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
20 Years to 75 Years
Enrollment
803 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Oct 18, 2026, 9:12 PM EDT
Completed Phase 3 Interventional Results available

Liraglutide 3mg (Saxenda) on Weight, Body Composition, Hormonal and Metabolic Parameters in Obese Women With PCOS

NCT03480022
View directory record Official record
Conditions
Pre Diabetes, Polycystic Ovary Syndrome, Obesity Android
Interventions
Liraglutide Pen Injector [Saxenda], Placebo Liraglutide Pen Injector
Drug
Lead sponsor
Woman's
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 7, 2021 · Synced Oct 18, 2026, 9:12 PM EDT
Completed Not applicable Interventional Results available

The Weigh Forward, Financial Incentives for Maintenance of Weight Loss

NCT02538783
View directory record Official record
Conditions
Obesity
Interventions
Escalating Lottery
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
30 Years to 80 Years
Enrollment
259 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Oct 18, 2026, 9:12 PM EDT
Active, not recruiting Phase 1 Interventional

Semaglutide (SEMA) for Alcohol Use Disorder (AUD) After Metabolic and Bariatric Surgery (MBS)

NCT07223983
View directory record Official record
Conditions
Alcohol Use Disorder, Weight Loss, Bariatric Surgery Patients
Interventions
Semaglutide 1.0 mg
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 18, 2026, 9:12 PM EDT
Active, not recruiting Phase 2 Interventional

A Study to Test Whether BI 3034701 Helps People to Lose Weight Who Live With Obesity or Overweight

NCT07662122
View directory record Official record
Conditions
Obesity, Overweight
Interventions
BI 3034701, Placebo matching BI 3034701
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years to 74 Years
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
19
States / cities
Birmingham, Alabama • West Hills, California • Miami, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 18, 2026, 9:12 PM EDT
Completed Phase 2 Interventional

Study To Determine The Effects And Safety Of A Weight Loss Compound On Overweight, Otherwise Healthy, Volunteers

NCT00479492
View directory record Official record
Conditions
Obesity
Interventions
CP-866,087, placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 65 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
4
States / cities
Orlando, Florida • Kalamazoo, Michigan • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2009 · Synced Oct 18, 2026, 9:12 PM EDT
Active, not recruiting Phase 4 Interventional

Sequential Therapy Anti-obesitY Medication With Muscle Preservation for Weight Loss and MaintEnance: A PragmAtic Randomized CoNtrolled Trial (STAY-LEAN Trial)

NCT06854614
View directory record Official record
Conditions
Obesity
Interventions
Comprehensive weight loss, Enhanced lifestyle changes, Tirzepatide, Naltrexone-Bupropion, Phentermine-Topiramate, Semaglutide (Wegovy®)
Other · Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
25 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 18, 2026, 9:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trial of a Water Beverage Intervention for Promoting Modest Weight Reduction in Free Living Adults

NCT01017783
View directory record Official record
Conditions
Obesity
Interventions
Dietary substitution A, Dietary Substitution B, Healthy Choices
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
318 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 3, 2011 · Synced Oct 18, 2026, 9:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Delicious Eating for Life in Southern Homes

NCT04302727
View directory record Official record
Conditions
Weight Loss, Diet, Healthy, Cardiovascular Risk Factor
Interventions
Med-South Weight Loss Intervention, WW
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 75 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Oct 18, 2026, 9:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Gastric Artery Embolization Trial for Lessening Appetite Nonsurgically

NCT02248688
View directory record Official record
Conditions
Arterial Embolization, Other Surgical Procedures, Obesity
Interventions
BeadBlock 300 - 500 Micron, Left Gastric Artery Embolization
Device · Procedure
Lead sponsor
Dayton Interventional Radiology
Other
Eligibility
22 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Oct 18, 2026, 9:12 PM EDT
Completed Not applicable Interventional

Avoiding Diabetes After Pregnancy Trial

NCT01923350
View directory record Official record
Conditions
Weight Reduction
Interventions
Weight Reduction Intervention, Weight Reduction Control Arm, Tested for diabetes, Not tested for diabetes
Behavioral
Lead sponsor
Social & Scientific Systems Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 15, 2013 · Synced Oct 18, 2026, 9:12 PM EDT
Completed Not applicable Interventional Results available

Health, Aging and Later-Life Outcomes

NCT05424042
View directory record Official record
Conditions
Aging
Interventions
In-Person Caloric Restriction, Remote Caloric Restriction, Time-restricted
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 18, 2026, 9:12 PM EDT
Active, not recruiting Phase 3 Interventional

Breast Cancer WEight Loss Study (BWEL Study)

NCT02750826
View directory record Official record
Conditions
Breast Ductal Carcinoma In Situ, Invasive Breast Carcinoma, Stage II Breast Cancer AJCC v6 and v7, Stage IIB Breast Cancer AJCC v6 and v7, Stage IIIA Breast Cancer AJCC v7, Stage IIIC Breast Cancer AJCC v7, Synchronous Bilateral Breast Carcinoma
Interventions
Health Education Program, Weight Loss Intervention
Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older · Female only
Enrollment
3,177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2030
U.S. locations
1464
States / cities
Daphne, Alabama • Mobile, Alabama • Anchorage, Alaska + 921 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 18, 2026, 9:12 PM EDT
Recruiting Not applicable Interventional

IMPACT-MACS: Adrenalectomy vs Semaglutide for Metabolic Outcomes in Mild Autonomous Cortisol Secretion

NCT07361874
View directory record Official record
Conditions
Mild Autonomous Cortisol Secretion (MACS), Autonomous Cortisol Secretion (ACS), Subclinical Cushing's, Mild Autonomous Cortisol Excess
Interventions
Intervention 1: Adrenalectomy, Intervention 2: Semaglutide
Procedure · Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 18, 2026, 9:12 PM EDT
Completed Not applicable Interventional Results available

Building Habits Together Online Weight Loss Program

NCT06154213
View directory record Official record
Conditions
Obesity
Interventions
Building Habits Together, Getting Healthy Together
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 30, 2025 · Synced Oct 18, 2026, 9:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acceptability and Feasibility of a Single-Session Online Parent-Focused Intervention Targeting Child Body Image Development

NCT07179068
View directory record Official record
Conditions
Eating Disorders, Body Image Disturbance, Weight Bias
Interventions
Child Body Image Development Workshop
Behavioral
Lead sponsor
University at Albany
Other
Eligibility
18 Years and older
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 18, 2026, 9:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using the Electronic Health Record to Guide Management of Newborn Weight Loss

NCT03655314
View directory record Official record
Conditions
Breastfeeding, Breastfeeding, Exclusive, Morbidity;Perinatal, Feeding, Bottle
Interventions
NEWT, Usual care
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
6 Hours to 96 Hours
Enrollment
2,682 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 26, 2020 · Synced Oct 18, 2026, 9:12 PM EDT