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ClinicalTrials.gov public records Last synced Oct 18, 2026, 10:55 AM EDT

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Showing 169–192 of 257 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Weight Loss Trial Clear all
Completed Phase 3 Interventional

Theory-Based Interventions for Smoking and Obesity (Challenge) Trial

NCT00040287
View directory record Official record
Conditions
Smoking, Obesity
Interventions
smoking cessation program, weight control program
Behavioral
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 60 Years
Enrollment
1,778 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1999
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 17, 2007 · Synced Oct 18, 2026, 10:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Independent Weight Loss Maintenance for Communities With Arthritis in North Carolina: the I-CAN Clinical Trial

NCT03832296
View directory record Official record
Conditions
Osteo Arthritis Knee
Interventions
Weight-Loss Maintenance, Health Education (Attention Control)
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
51 Years and older
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
3
States / cities
Chapel Hill, North Carolina • Clyde, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 26, 2021 · Synced Oct 18, 2026, 10:55 AM EDT
Completed Not applicable Interventional

The Arthritis, Diet, and Activity Promotion Trial

NCT00979043
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Dietary Weight-loss, Exercise
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years and older
Enrollment
318 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2000
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 14, 2023 · Synced Oct 18, 2026, 10:55 AM EDT
Completed Not applicable Interventional

Study Testing Patient Decision Tools Related to the Risks and Benefits of Weight Loss Surgery

NCT00666952
View directory record Official record
Conditions
Obesity, Morbid, Obesity, Decision Aids, Bariatric Surgery
Interventions
Video Decision Aid, Booklet Decision Aid
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
20 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 13, 2017 · Synced Oct 18, 2026, 10:55 AM EDT
Completed Not applicable Interventional Results available

Ignite Pilot: Goal Setting in a Digital Weight Loss Intervention

NCT05715242
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss, Health Behavior
Interventions
Core Behavioral Weight Loss Intervention, Easier Step Goal, Harder Step Goal, Easier Calorie Goal, Harder Calorie Goal, Easier Eating Window Goal, Harder Eating Window Goal, Easier Red Zone Food Goal, Harder Red Zone Food Goal
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 18, 2026, 10:55 AM EDT
Completed Not applicable Interventional Results available

Financial vs. Non-Financial Rewards for Weight Loss and Weight Maintenance

NCT02957539
View directory record Official record
Conditions
Obesity
Interventions
Financial rewards, Non-Financial rewards
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 69 Years
Enrollment
274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 28, 2023 · Synced Oct 18, 2026, 10:55 AM EDT
Completed Not applicable Interventional

Prevention of Diabetes Using Mobile-enabled, Virtual Delivery of the National Diabetes Prevention Program

NCT03865342
View directory record Official record
Conditions
PreDiabetes
Interventions
Noom Coach DPP
Behavioral
Lead sponsor
Noom Inc.
Industry
Eligibility
18 Years and older
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Oct 18, 2026, 10:55 AM EDT
Completed Not applicable Interventional

A Trial of Two Diets for Weight and Diabetes Management

NCT00729196
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Obesity
Interventions
Lifestyle Modification
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 1, 2011 · Synced Oct 18, 2026, 10:55 AM EDT
Terminated Not applicable Interventional Results available

Multimodal Treatment Strategy for Cancer Cachexia

NCT00625742
View directory record Official record
Conditions
Advanced Cancer, Cachexia
Interventions
Graded Resistance Training, Aerobic Exercise, Melatonin, Juven, Atenolol, Ibuprofen
Behavioral · Drug · Dietary Supplement
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 12, 2016 · Synced Oct 18, 2026, 10:55 AM EDT
Recruiting Phase 2Phase 3 Interventional

Visugromab in Cachexia International Trial

NCT07112196
View directory record Official record
Conditions
Cancer-associated Cachexia
Interventions
Visugromab (CTL-002), Placebo
Drug
Lead sponsor
CatalYm GmbH
Industry
Eligibility
18 Years and older
Enrollment
518 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
10
States / cities
Norwich, Connecticut • Clermont, Florida • Orange City, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 18, 2026, 10:55 AM EDT
Completed Not applicable Interventional

Study of an International Commercial Program on Weight Loss and Health Outcomes

NCT03571893
View directory record Official record
Conditions
Weight Loss, Weight Change, Body, Obesity, Diet Modification
Interventions
Weight Watchers Freestyle (Flex), DIY Personal Plan
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 75 Years
Enrollment
373 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 13, 2020 · Synced Oct 18, 2026, 10:55 AM EDT
Completed Not applicable Interventional Results available

Cryovagotomy Diabetes Trial

NCT04276051
View directory record Official record
Conditions
Diabetes Type 2, Diabetes Mellitus, Obesity
Interventions
Cryoablation of the Vagus Nerve, Lifestyle Intervention
Device · Behavioral
Lead sponsor
Emory University
Other
Eligibility
22 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
5
States / cities
Atlanta, Georgia • Johns Creek, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 8, 2023 · Synced Oct 18, 2026, 10:55 AM EDT
Completed Not applicable Interventional Results available

Obalon Balloon System Pivotal IDE (SMART) Trial

NCT02235870
View directory record Official record
Conditions
Obesity
Interventions
Obalon Intragastric Balloons, Sham Device, Nutrition and Lifestyle Program
Device · Behavioral
Lead sponsor
Obalon Therapeutics, Inc.
Industry
Eligibility
22 Years to 64 Years
Enrollment
711 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
15
States / cities
Scottsdale, Arizona • Anaheim, California • Coronado, California + 12 more
Source: ClinicalTrials.gov public record
Updated Mar 8, 2018 · Synced Oct 18, 2026, 10:55 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Study of Behavioral Weight Loss Therapy for Obesity and Binge Eating in Monolingual Hispanic Persons

NCT00516919
View directory record Official record
Conditions
Obesity, Binge Eating
Interventions
Xenical + behavioral intervention, Behavioral intervention + placebo
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 2, 2020 · Synced Oct 18, 2026, 10:55 AM EDT
Terminated No phase listed Observational

Identify microRNAs in Cachexia in Pancreatic Carcinoma

NCT05275075
View directory record Official record
Conditions
Resectable Pancreatic Adenocarcinoma
Interventions
Pancreatic cancer microRNA and messenger RNA expression.
Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 18, 2026, 10:55 AM EDT
Not listed Phase 3 Interventional

A Weight-Loss Program in Helping Obese Black Women Lose Weight

NCT00859989
View directory record Official record
Conditions
Breast Cancer, Obesity, Weight Changes
Interventions
behavioral dietary intervention, exercise intervention, telephone-based intervention, counseling intervention, educational intervention, immunoenzyme technique, laboratory biomarker analysis, questionnaire administration, study of socioeconomic and demographic variables, evaluation of cancer risk factors, support group therapy
Behavioral · Other · Procedure
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
30 Years to 50 Years · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 18, 2013 · Synced Oct 18, 2026, 10:55 AM EDT
Not yet recruiting Not applicable Interventional

Endoscopic Sleeve Gastroplasty Technique Comparison for Weight Loss

NCT06299644
View directory record Official record
Conditions
Obesity, Obesity, Morbid, Metabolic Disease, Weight, Body
Interventions
Endoscopic Sleeve Gastroplasty - Belt and Suspenders, Endoscopic Sleeve Gastroplasty - Belt
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 18, 2026, 10:55 AM EDT
Not yet recruiting Not applicable Interventional

Simplifying Diet Tracking in a Digital Weight Loss Intervention

NCT07601061
View directory record Official record
Conditions
Overweight, Obesity, Weight Loss, Health Behavior, Lifestyle Intervention
Interventions
Simplified Dietary Self-Monitoring, Detailed Dietary Self-Monitoring, Core Behavioral Weight Loss Intervention
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
328 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 18, 2026, 10:55 AM EDT
Completed Not applicable Interventional Results available

An Addiction-Based Mobile Health Weight Loss Intervention With Coaching

NCT03500835
View directory record Official record
Conditions
Pediatric Obesity, Mobile Technology, Addiction
Interventions
App, Coaching, Clinic: Modified KidsNFitness
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
14 Years to 18 Years
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 6, 2024 · Synced Oct 18, 2026, 10:55 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Evaluation of Safety, Efficacy and Thermogenesis-induction of RZL-012 in Overweight and Obese Volunteers

NCT03171415
View directory record Official record
Conditions
Obesity, Weight Loss, Overweight and Obesity
Interventions
RZL-012, Placebo
Drug
Lead sponsor
Raziel Therapeutics Ltd.
Industry
Eligibility
20 Years to 60 Years · Male only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
West Bend, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 21, 2019 · Synced Oct 18, 2026, 10:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Trial of the Ideal Protein System Versus Low Fat Diet for Weight Loss

NCT03515889
View directory record Official record
Conditions
Weight Loss
Interventions
Ideal Protein Weight Loss Method, Standard Weight Loss
Behavioral
Lead sponsor
Tulane University
Other
Eligibility
22 Years to 79 Years
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Bogalusa, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 22, 2024 · Synced Oct 18, 2026, 10:55 AM EDT
Completed Not applicable Interventional Results available

Diabetes Data-Assisted Remission Trial (DDART)

NCT04663061
View directory record Official record
Conditions
Type 2 Diabetes, Obesity
Interventions
Medical weight loss, Diabetes education, Continuous glucose monitoring
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 18, 2026, 10:55 AM EDT
Completed Not applicable Interventional

Weight Management Demonstration Project: HEALTH

NCT01307280
View directory record Official record
Conditions
Weight Loss
Interventions
RCT1, RCT2, RCT3
Behavioral
Lead sponsor
RTI International
Other
Eligibility
18 Years to 64 Years
Enrollment
2,395 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
3
States / cities
Swansea, Illinois • Research Triangle Park, North Carolina • Fairborn, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 26, 2012 · Synced Oct 18, 2026, 10:55 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effectiveness of ResArgin on Adult's Body Composition and Health

NCT06601049
View directory record Official record
Conditions
Weight Loss
Interventions
ResArgin
Dietary Supplement
Lead sponsor
Dr. Heather Hausenblaus
Other
Eligibility
25 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 18, 2026, 10:55 AM EDT