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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Weight Maintenance Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Exercise, Brain Activity, and Weight Maintenance

NCT06511310
View directory record Official record
Conditions
Obesity, Weight Gain, Bariatric Surgery Candidate, Appetitive Behavior
Interventions
Exercise
Other
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 3, 2025 · Synced Jun 10, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow

NCT00634608
View directory record Official record
Conditions
Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy, Bursitis, Depression, Anxiety, Diabetes Mellitus, Esophageal Reflux, HIV Infections, Hyperlipidemia, Hypertension, Insomnia, Irritable Bowel Syndrome, Obesity, Osteoporosis (Senile), Shoulder Pain, Sinusitis, Symptomatic Menopause, Urinary Incontinence, Urinary Tract Infection, Vaginitis
Interventions
Health Information Prescription
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 29, 2016 · Synced Jun 10, 2026, 10:42 PM EDT
Recruiting Not applicable Interventional

SMART to Optimize an Intervention to Maintain Health Improvements After Cardiac Rehabilitation

NCT06886789
View directory record Official record
Conditions
Cardiovascular Diseases, Cardiac Rehabilitation
Interventions
Text Messaging, Fully Automated Online Program, Low-Intensity Cardiac Rehabilitation Maintenance Program, High Intensity Cardiac Rehabilitation Maintenance Program
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Jun 10, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Alternate Day Fasting Combined With a High Protein Background Diet

NCT03528317
View directory record Official record
Conditions
Obesity
Interventions
Alternate day fasting
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 65 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 7, 2021 · Synced Jun 10, 2026, 10:42 PM EDT
Recruiting Not applicable Interventional

Cooking Skills to Improve Long-Term Weight Loss in Young Adults With Intellectual Disabilities

NCT06961591
View directory record Official record
Conditions
Intellectual Disability, Overweight and Obesity
Interventions
Weight Loss Plus Cooking, Traditional Weight Loss
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 35 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 5, 2025 · Synced Jun 10, 2026, 10:42 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Identification of Phenotypic Factors That Predict Success for Weight Loss and Long-term Weight Maintenance

NCT02043457
View directory record Official record
Conditions
Obesity
Interventions
phenotyping
Other
Lead sponsor
University of Michigan
Other
Eligibility
15 Years to 75 Years
Enrollment
3,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 2, 2025 · Synced Jun 10, 2026, 10:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Retrospective Chart Review of the 5 & 2 & 2 and 4 & 2 & 1 Plans

NCT02150837
View directory record Official record
Conditions
Obesity
Interventions
5 & 2 & 2 Plan, 4 & 2 & 1 Plan
Other
Lead sponsor
Medifast, Inc.
Industry
Eligibility
18 Years and older
Enrollment
372 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Owings Mills, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 12, 2019 · Synced Jun 10, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lose 2 Win A Novel Method to Motivate Weight Loss Maintenance Among College Students

NCT02021383
View directory record Official record
Conditions
Overweight, Obese
Interventions
Bi-weekly in person meetings with a Registered Dietician, Financial incentives for weight loss maintenance
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 24 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 12, 2019 · Synced Jun 10, 2026, 10:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Real-Time Assessment of Food Craving, Use, and Triggers During Outpatient Treatment of Obesity: A Development and Feasibility Study

NCT00198783
View directory record Official record
Conditions
Obesity, Weight Maintenance
Interventions
Not listed
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 3, 2007 · Synced Jun 10, 2026, 10:42 PM EDT
Completed Not applicable Interventional

mDiet: A Text Message Intervention for Weight Loss

NCT01171586
View directory record Official record
Conditions
Overweight, Weight Loss
Interventions
mDiet
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 60 Years
Enrollment
318 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Dec 4, 2014 · Synced Jun 10, 2026, 10:42 PM EDT
Recruiting Phase 3 Interventional

AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss

NCT07503210
View directory record Official record
Conditions
Obesity
Interventions
NNC0487-0111, Placebo (matched to NNC0487-0111)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
13
States / cities
Anniston, Alabama • Walnut Creek, California • Orlando, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Jun 10, 2026, 10:42 PM EDT
Completed Not applicable Interventional

Individualized Diet Improvement Program for Weight Loss and Maintenance, Cohort 1

NCT04605653
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss, Diet Habit
Interventions
Weight Management Intervention
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 64 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 2, 2020 · Synced Jun 10, 2026, 10:42 PM EDT
Completed Not applicable Interventional

Partnerships to Overcome Obesity Disparities in Hawaii: 18-month CBPR Study

NCT01093924
View directory record Official record
Conditions
Obesity
Interventions
PILI 'Ohana 18-month weight loss maintenance
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
4
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Nov 14, 2013 · Synced Jun 10, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Eat Well for Life: A Weight Loss Maintenance Study

NCT01849627
View directory record Official record
Conditions
Obesity
Interventions
Low-ED, Energy Balance
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
18 Years to 70 Years
Enrollment
345 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2025
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Jun 10, 2026, 10:42 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

International Weight Control Registry

NCT04907396
View directory record Official record
Conditions
Weight Loss, Overweight, Obesity
Interventions
Not listed
Lead sponsor
Tufts University
Other
Eligibility
18 Years and older
Enrollment
100,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
7
States / cities
Birmingham, Alabama • Denver, Colorado • Kansas City, Kansas + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jun 10, 2026, 10:42 PM EDT
Completed Not applicable Interventional

Postpartum Weight Loss and Sleep Amongst Obese Women

NCT01968330
View directory record Official record
Conditions
Obesity, Sleep Disordered Breathing, Weight Loss, Postpartum, Insomnia
Interventions
Go!®to sleep
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older · Female only
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 19, 2016 · Synced Jun 10, 2026, 10:42 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Interventional Testing of Gene-environment Interactions Via the Verifomics Mobile Application

NCT02758990
View directory record Official record
Conditions
Obesity, Rhinitis, Rhinitis, Allergic, Respiratory Sounds, Dyspnea, Headache, Migraine Disorders, Arthritis, Arthralgia, Anxiety, Sleep Initiation and Maintenance Disorders, Sleep Deprivation
Interventions
Vitamin A, Vitamin B6, Vitamin C, Nicotinamide, Vitamin D3, Vitamin E, Broccoli, Spinach, Caffeine, Coffee, Axon Eyewear, Chocolate
Dietary Supplement · Other · Device
Lead sponsor
Verifomics LLC
Industry
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 1, 2017 · Synced Jun 10, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exercise After Clinically Significant Weight Loss

NCT03685123
View directory record Official record
Conditions
Obesity, Sedentary Lifestyle, Insulin Resistance
Interventions
Physical activity recommendations, Weight maintenance recommendations, OPTIFAST weight loss
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 2, 2024 · Synced Jun 10, 2026, 10:42 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Engaging Motivation for the Prevention of Weight Regain

NCT01169428
View directory record Official record
Conditions
Obesity
Interventions
Mindfulness Based Weight Loss Maintenance (MBWLM), Behavioral: Standard Behavioral Weight-Loss Maintenence
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
2
States / cities
Durham, North Carolina • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 13, 2013 · Synced Jun 10, 2026, 10:42 PM EDT
Not yet recruiting Not applicable Interventional

Scalable Behavioral Program for Weight Loss Maintenance After GLP-1 and Anti-Obesity Medication Discontinuation

NCT07535892
View directory record Official record
Conditions
Weight Loss, GLP - 1, Weight Loss Maintenance, Obesity & Overweight
Interventions
Weight Loss Maintenance Program (Foundational), Mom's Meals, YMCA Membership, SKY Meditation Program
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Jun 10, 2026, 10:42 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Optimizing an Extended Care Intervention to Promote Weight Loss Maintenance

NCT06785064
View directory record Official record
Conditions
Obesity Prevention, Weight Change, Weight Loss, Weight Loss Maintenance
Interventions
Reduced Food Variety (RFV), Home-based Resistance Training (HBRT), Buddy Training and Support (BTS), Acceptance and Commitment (ACT) Workshops
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
544 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Jun 10, 2026, 10:42 PM EDT
Completed Not applicable Interventional

Feasibility and Preliminary Efficacy of a Reverse Diet as a Novel Weight Loss Maintenance Strategy for Weight-Reduced Adults With Overweight/Obesity

NCT03560635
View directory record Official record
Conditions
Overweight and Obesity, Weight Loss Maintenance, Dietary Habits
Interventions
Weight Loss Maintenance (Control vs. Reverse Diet)
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 18, 2022 · Synced Jun 10, 2026, 10:42 PM EDT
Active, not recruiting Phase 2 Interventional

Effects of Mirtazapine on Appetite in Advanced Cancer Patients

NCT00488072
View directory record Official record
Conditions
Advanced Cancer, Anorexia, Weight Loss, Insomnia
Interventions
Mirtazapine, Placebo
Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Jun 10, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of Methadone Maintenance Therapy on Food Reward Processing in Opioid Dependence

NCT03575273
View directory record Official record
Conditions
Opioid Dependence, Obesity
Interventions
Sniffin' Sticks Odor Identification and Hedonic Scale, Sucrose Taste Preference Assessment, Food Preferences Task, Progressive Ratio (PR) Task, Clinical Electrophysiology, Standardized Meal and Hunger and Satiety Ratings
Behavioral · Procedure · Dietary Supplement
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 15, 2020 · Synced Jun 10, 2026, 10:42 PM EDT