Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 4, 2026, 10:40 PM EDT

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Showing 1–24 of 36 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Weight Loss, Weight Gain, Obesity
Interventions
Intensive lifestyle change therapy, Tirzepatide
Behavioral · Drug
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Completed No phase listed Observational Accepts healthy volunteers

Gut Microbiota Post Roux-en-Y Gastric Bypass Surgery

NCT02654496
Conditions
Obesity
Interventions
Meal challenge
Other
Lead sponsor
North Dakota State University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Fargo, North Dakota
Recruiting Not applicable Interventional Accepts healthy volunteers

Testing a Tailored Approach to Long-Term Weight Loss Success

NCT07577765
Conditions
Weight Loss, Weight Regain, Obesity & Overweight
Interventions
Adaptive weight regain prevention
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Weight Regain Post Bariatric Surgery
Interventions
Naltrexone HCl/Bupropion HCl Placebo, Naltrexone HCl/Bupropion HCl
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Chicago, Illinois • Boston, Massachusetts
Completed Not applicable Interventional Results available

Empowered With Movement to Prevent Obesity and Weight Regain

NCT02923674
Conditions
Obesity, Weight Loss, Sedentary Lifestyle
Interventions
Weight loss, Exercise, Sitless
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years to 85 Years
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Obesity, Weight Loss
Interventions
Rimonabant (SR141716)
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
3,045 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
47
States / cities
Birmingham, Alabama • Phoenix, Arizona • Concord, California + 42 more
Withdrawn Not applicable Interventional Accepts healthy volunteers

Weight Regain Study After Bariatric Surgery-A Pilot Project

NCT02754453
Conditions
Behavioral, Activity, Weight Loss
Interventions
Behavioral lifestyle intervention
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Obesity
Interventions
Medically tailored meals, Noom®, Usual care
Other · Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Obesity
Interventions
Saxenda, Placebo
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
New York, New York
Conditions
Obesity
Interventions
Weight loss
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
25 Years to 59 Years
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
New York, New York • Philadelphia, Pennsylvania
Conditions
Obesity
Interventions
Acceptance and Commitment Therapy-Based Physical Activity Intervention, Physical Activity Education Control
Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Hartford, Connecticut
Completed Phase 2 Interventional Accepts healthy volunteers

Engaging Motivation for the Prevention of Weight Regain

NCT01169428
Conditions
Obesity
Interventions
Mindfulness Based Weight Loss Maintenance (MBWLM), Behavioral: Standard Behavioral Weight-Loss Maintenence
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
2
States / cities
Durham, North Carolina • Philadelphia, Pennsylvania
Conditions
Obesity
Interventions
Eating Behavior Evaluation, Measurement of Functional gastric volume, Measurement of gastric pouch and GJ size
Behavioral · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
21 Years to 60 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Energy Expenditure
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Overweight and Obesity, Weight Loss Maintenance, Dietary Habits
Interventions
Weight Loss Maintenance (Control vs. Reverse Diet)
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Overweight, Obesity, Weight Loss
Interventions
150 Min/Week, 225 Min/Week, 300 Min/Week
Behavioral
Lead sponsor
University of Kansas
Other
Eligibility
21 Years to 55 Years
Enrollment
287 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Lawrence, Kansas
Completed Not applicable Interventional Accepts healthy volunteers

Role of Dairy Products in Weight Maintenance

NCT00686426
Conditions
Obesity, Weight Gain
Interventions
Dairy Foods
Dietary Supplement
Lead sponsor
University of Tennessee
Other
Eligibility
25 Years to 50 Years
Enrollment
338 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
2
States / cities
Lawrence, Kansas • Knoxville, Tennessee
Conditions
Obesity
Interventions
CP-945,598, Non-pharmacological weight loss program (NPP), Low Calorie Diet
Drug · Behavioral
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 70 Years
Enrollment
699 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
9
States / cities
La Jolla, California • Denver, Colorado • Baton Rouge, Louisiana + 6 more
Conditions
Weight Regain, Weight Recidivism, Obesity Recidivism, Clinically Severe Obesity
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Fresno, California
Conditions
Obesity
Interventions
Phentermine Pill, Orforglipron
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Weight Regain, Weight Loss
Interventions
TORe with OverStitch, Intensive lifestyle modification
Device · Behavioral
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
9
States / cities
Irvine, California • Stanford, California • Jacksonville, Florida + 6 more
Conditions
Obesity
Interventions
Behavioral intervention for regain after bariatric surgery
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Rochester, Minnesota
Completed Not applicable Interventional Accepts healthy volunteers Results available

Eating Mindfully to Prevent Weight Regain

NCT04847843
Conditions
Weight Loss, Weight Gain, Eating Behavior, Obesity, Bariatric Surgery Candidate
Interventions
Mindfulness Orientated Recovery Enhancement, Control Intervention
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Completed Not applicable Interventional Accepts healthy volunteers

Using the Energy Gap to Prevent Weight Regain

NCT00429650
Conditions
Obesity
Interventions
increased exercise, diet, Exercise and Diet
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
19 Years to 45 Years
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
1
States / cities
Denver, Colorado