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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Weightloss Clear all
Completed Phase 3 Interventional Accepts healthy volunteers

Effect of Weight Loss and Exercise on Liver and Muscle Fat in Obese Elderly

NCT00779207
View directory record Official record
Conditions
Obesity
Interventions
weight loss and exercise, weight loss
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
65 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 23, 2008 · Synced Sep 22, 2026, 2:32 PM EDT
Recruiting Not applicable Interventional

Long-term, Substantial Weight Loss and Insulin Regulation of Lipolysis

NCT03868592
View directory record Official record
Conditions
Obesity, Morbid
Interventions
Gastric sleeve/bariatric surgery
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Sep 22, 2026, 2:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Weight Loss on Bone in Men

NCT00472745
View directory record Official record
Conditions
Weight Loss, BMD
Interventions
Weight Loss, Weight Maintenance
Behavioral
Lead sponsor
Rutgers University
Other
Eligibility
50 Years to 72 Years · Male only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Sep 22, 2026, 2:32 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Effect of Revival Soy on Weight Loss and Skin, Hair, and Nails in Premenopausal Women

NCT00352157
View directory record Official record
Conditions
Skin Aging, Weight Loss
Interventions
Revival Soy Dietary Supplement
Behavioral
Lead sponsor
Physicians Pharmaceuticals, Inc.
Industry
Eligibility
25 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
High Point, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 20, 2009 · Synced Sep 22, 2026, 2:32 PM EDT
Completed Not applicable Interventional

Health At Every Size and Acceptance and Commitment Therapy vs. Behavioral Weight Loss for Obesity and Depression in Women

NCT02501239
View directory record Official record
Conditions
Depression, Obesity
Interventions
Accept Yourself!, Weight Watchers
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Apr 25, 2018 · Synced Sep 22, 2026, 2:32 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Stomach Intestinal Pylorus-Sparing Bariatric Surgery

NCT05094830
View directory record Official record
Conditions
Obesity
Interventions
Stomach Intestinal Pylorus-Sparing (SIPS) Procedure
Procedure
Lead sponsor
Bradley Needleman
Other
Eligibility
18 Years to 89 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Sep 22, 2026, 2:32 PM EDT
Completed Not applicable Interventional

The Use of the Internet to Facilitate Weight Loss and Maintenance.

NCT00008827
View directory record Official record
Conditions
Obesity
Interventions
Behavioral weight loss
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2001
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jan 13, 2010 · Synced Sep 22, 2026, 2:32 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Effect of Daily Glucomannan in Overweight Patients

NCT01485718
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Glucomannan, Placebo
Dietary Supplement
Lead sponsor
ProMedica Health System
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 12, 2011 · Synced Sep 22, 2026, 2:32 PM EDT
Completed Phase 3 Interventional

Lifestyle, Exercise and Nutrition Study 1

NCT02109068
View directory record Official record
Conditions
Breast Cancer, Weight Loss
Interventions
Weight Loss Counseling- Phone, Weight Loss Counseling- In-Person
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 8, 2014 · Synced Sep 22, 2026, 2:32 PM EDT
Recruiting Not applicable Interventional

Plant-Based Online Weight Loss Through Education and Resources Program and Study

NCT07095543
View directory record Official record
Conditions
Type 2 Diabetes, Overweight and Obese Adults
Interventions
Low-fat, vegan diet
Behavioral
Lead sponsor
Physicians Committee for Responsible Medicine
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Sep 22, 2026, 2:32 PM EDT
Completed Phase 2 Interventional Results available

Ex Vivo-activated Autologous Lymph Node Lymphocytes in Treating Patients With Chronic Lymphocytic Leukemia

NCT02530515
View directory record Official record
Conditions
Anemia, Cancer Fatigue, Chronic Lymphocytic Leukemia, Fever, Infectious Disorder, Lymphadenopathy, Lymphocytosis, Night Sweats, Prolymphocytic Leukemia, Recurrent Chronic Lymphocytic Leukemia, Richter Syndrome, Secondary Malignant Neoplasm, Thrombocytopenia, Weight Loss
Interventions
Ex Vivo-activated Autologous Lymph Node Lymphocytes, Laboratory Biomarker Analysis
Biological · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Not listed
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 28, 2019 · Synced Sep 22, 2026, 2:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Milk Protein Concentrate on Overall Health During Weight Loss in Overweight/Obese Adults

NCT01692860
View directory record Official record
Conditions
Sarcopenia, Metabolic Disease, High Blood Pressure
Interventions
Energy Restriction
Other
Lead sponsor
Purdue University
Other
Eligibility
35 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 3, 2015 · Synced Sep 22, 2026, 2:32 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

ABLATE WEIGHT 2 (Single-Stage Fundic Ablation Plus ESG for Weight Loss)

NCT05992103
View directory record Official record
Conditions
Obesity
Interventions
Fundic Ablation in Combination with Endoscopic Sleeve Gastroplasty, Fundic Mucosal Ablation with ERBE HybridAPC, Apollo ESG
Procedure · Device
Lead sponsor
True You Weight Loss
Other
Eligibility
21 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Cary, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Sep 22, 2026, 2:32 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

The DINE Study-Diet Intervention to Negate Diabetes Study (Improving Weight Loss Outcomes for African Americans)

NCT00599040
View directory record Official record
Conditions
Diabetes, Hypertension, Insulin Resistance
Interventions
The DASH diet with weight loss, The DASH diet without weight loss, Dairy diet
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 17, 2013 · Synced Sep 22, 2026, 2:32 PM EDT
Completed Not applicable Interventional

Intensive Diet and Exercise for Improving Knee Osteoarthritis in Obese and Overweight Older Adults

NCT00381290
View directory record Official record
Conditions
Osteoarthritis
Interventions
Diet, Exercise
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
55 Years and older
Enrollment
454 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Sep 22, 2026, 2:32 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Safety and Efficacy of APD356 in the Treatment of Obesity

NCT00116740
View directory record Official record
Conditions
Obesity
Interventions
APD356
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 11, 2019 · Synced Sep 22, 2026, 2:32 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Lorcaserin: Real World Experience in an Insurance-Based Weight Management Clinic

NCT03552107
View directory record Official record
Conditions
Obesity, Weight Loss, Overweight
Interventions
Lorcaserin
Drug
Lead sponsor
Scripps Whittier Diabetes Institute
Other
Eligibility
18 Years and older
Enrollment
157 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 30, 2019 · Synced Sep 22, 2026, 2:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Gender- and Culturally-Sensitive Weight Loss Intervention for Hispanic Males

NCT02783521
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Counseling sessions, Wait List Control
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 64 Years · Male only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 31, 2017 · Synced Sep 22, 2026, 2:32 PM EDT
Completed Not applicable Interventional Results available

Gaining Optimism After Weight Loss Surgery (GOALS) II

NCT04868032
View directory record Official record
Conditions
Bariatric Surgery
Interventions
Positive Psychology-Motivational Interviewing, Physical Activity Education Control
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 22, 2026, 2:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Weight Loss Outcomes Through Body Image Enhancement

NCT05090293
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Experimental: Lifestyle Intervention with Body Image Treatment (LIBI), Lifestyle Intervention (LI)
Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years and older · Female only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Nov 2, 2022 · Synced Sep 22, 2026, 2:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Comparative Effectiveness Study Evaluating the Effects of Thermogenic Supplements on Body Composition

NCT01423019
View directory record Official record
Conditions
Weight Loss
Interventions
Advantra Z, Advantra Z + Naringin + Hesperiden, Sugar pill
Dietary Supplement · Other
Lead sponsor
Integrative Health Technologies, Inc.
Network
Eligibility
21 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 22, 2012 · Synced Sep 22, 2026, 2:32 PM EDT
Completed Phase 2 Interventional Results available

Study of GTx-024 on Muscle Wasting (Cachexia) Cancer.

NCT00467844
View directory record Official record
Conditions
Cachexia
Interventions
GTx-024, Placebo
Drug
Lead sponsor
GTx
Industry
Eligibility
Not listed
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
50
States / cities
Anchorage, Alaska • Fayetteville, Arkansas • Corona, California + 41 more
Source: ClinicalTrials.gov public record
Updated Jul 10, 2014 · Synced Sep 22, 2026, 2:32 PM EDT
Terminated Phase 3 Interventional Results available

Treatment of Cancer-associated Anorexia Using Megestrol Acetate Concentrated Suspension

NCT00637806
View directory record Official record
Conditions
Anorexia, Cachexia, Weight Loss
Interventions
Megestrol acetate concentrated suspension 110 mg/mL, Megestrol acetate concentrated suspension 60 mg/mL, Placebo
Drug
Lead sponsor
Par Pharmaceutical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
4
States / cities
Anaheim, California • Flat Rock, North Carolina • High Point, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated May 1, 2016 · Synced Sep 22, 2026, 2:32 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Evaluation of the Healthy Lifestyle Program on Cognitive Outcomes

NCT03926481
View directory record Official record
Conditions
Obesity
Interventions
Evaluate Healthy Lifestyle Program on cognitive outcomes
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
65 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 2, 2022 · Synced Sep 22, 2026, 2:32 PM EDT