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ClinicalTrials.gov public records Last synced Oct 21, 2026, 7:21 PM EDT

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Showing 1–24 of 65 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Wheezing Clear all
Completed Phase 2 Interventional Results available

Crossover Study to Evaluate the Efficacy, Safety and Tolerability of Different Doses of Indacaterol in Patients With Persistent Asthma

NCT01959412
View directory record Official record
Conditions
Asthma
Interventions
Indacaterol 27.5 mcg, Indacaterol 37.5, Indacaterol 55 mcg, Indacaterol 75 mcg, Indacaterol 150 mcg, Placebo
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
12
States / cities
Huntington Beach, California • Los Angeles, California • Mission Viejo, California + 9 more
Source: ClinicalTrials.gov public record
Updated May 6, 2015 · Synced Oct 21, 2026, 7:21 PM EDT
Completed Not applicable Interventional

Treatment of Persistent Wheezing in Infants and Children

NCT00301171
View directory record Official record
Conditions
Asthma, Respiratory Sounds
Interventions
Inhaled Fluticasone
Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
Up to 36 Months
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 29, 2016 · Synced Oct 21, 2026, 7:21 PM EDT
Not listed No phase listed Observational

Clinical Validation of Omron WheezeScan

NCT04144699
View directory record Official record
Conditions
Asthma in Children, Bronchitis, Bronchiolitis
Interventions
Not listed
Lead sponsor
Omron Healthcare Co., Ltd.
Industry
Eligibility
3 Months to 8 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
15
States / cities
Chamblee, Georgia • Chicago, Illinois • Joliet, Illinois + 11 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2021 · Synced Oct 21, 2026, 7:21 PM EDT
Completed No phase listed Observational

A Study to Assess Benign Joint Hypermobility Syndrome in Children With a History of Wheezing or Asthma

NCT02163096
View directory record Official record
Conditions
Benign Joint Hypermobility Syndrome, Wheezing, Asthma
Interventions
Not listed
Lead sponsor
University of Louisville
Other
Eligibility
6 Years to 16 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
3
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 8, 2016 · Synced Oct 21, 2026, 7:21 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cough Reflex Sensitivity and Bronchial Hyper-responsiveness

NCT01777867
View directory record Official record
Conditions
Gastroesophageal Reflux Disease, Chronic Cough, Broncho-hyperreactivity
Interventions
Cough Reflex Sensitivity, Methacholine Challenge
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 17, 2017 · Synced Oct 21, 2026, 7:21 PM EDT
Recruiting Phase 2 Interventional

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma

NCT06977581
View directory record Official record
Conditions
Asthma
Interventions
PF-07275315, Placebo
Drug · Other
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 75 Years
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
36
States / cities
Mobile, Alabama • Chandler, Arizona • Lancaster, California + 29 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 21, 2026, 7:21 PM EDT
Completed Phase 3 Interventional

Inhaled Albuterol Sulfate For Acute Wheezing Due To Obstructive Airways Disease In Children

NCT00144846
View directory record Official record
Conditions
Asthma
Interventions
albuterol sulfate inhalation aerosol
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
Up to 23 Months
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
27
States / cities
Hoover, Alabama • Fort Mohave, Arizona • Jonesboro, Arkansas + 24 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2016 · Synced Oct 21, 2026, 7:21 PM EDT
Completed Phase 2 Interventional Results available

A Study to Evaluate the Dosing of AMG 827 for Subjects With Inadequately Controlled Asthma

NCT01199289
View directory record Official record
Conditions
Asthma
Interventions
AMG 827, Placebo
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years to 65 Years
Enrollment
315 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
22
States / cities
Encinitas, California • Huntington Beach, California • Los Angeles, California + 19 more
Source: ClinicalTrials.gov public record
Updated Nov 26, 2021 · Synced Oct 21, 2026, 7:21 PM EDT
Completed No phase listed Observational

Early Life Factors and Respiratory Health in Mexico City Children

NCT00342758
View directory record Official record
Conditions
Respiratory Ilness
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
Not listed
Enrollment
6,800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 21, 2026, 7:21 PM EDT
Completed Phase 1 Interventional Results available

A Study of the Pharmacokinetics, Safety and Tolerability of Single Doses of VR647 Inhalation Suspension Administered Using the VR647 Inhalation System in Children With Wheezing, Reactive Airway Disease or Mild Asthma

NCT03421730
View directory record Official record
Conditions
Wheezing, Reactive Airway Disease, Mild Asthma
Interventions
VR647 Inhalation Suspension (budesonide) 1 mg/2 mL delivered by the VR647 Inhalation System, 1 mg/2 mL Pulmicort Respules delivered by a conventional jet nebulizer
Combination Product
Lead sponsor
Vectura Limited
Industry
Eligibility
4 Years to 8 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
3
States / cities
Colorado Springs, Colorado • Raleigh, North Carolina • Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Oct 21, 2019 · Synced Oct 21, 2026, 7:21 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Allergy Immunotherapy for the Reduction of Asthma

NCT01028560
View directory record Official record
Conditions
Wheezing, Asthma, Allergy
Interventions
Allergen extracts (subcutaneous injections), Standard of care
Biological · Other
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Months to 3 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 28, 2019 · Synced Oct 21, 2026, 7:21 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Safety of LAIV4 in Children With Asthma

NCT03600428
View directory record Official record
Conditions
Asthma in Children, Vaccine Adverse Reaction, Vaccine Reaction, Asthma, Wheezing, Influenza
Interventions
Live Attenuated Influenza Vaccine (LAIV), Inactivated Influenza Vaccine (IIV)
Biological
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
5 Years to 11 Years
Enrollment
152 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
3
States / cities
Durham, North Carolina • Cincinnati, Ohio • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 16, 2021 · Synced Oct 21, 2026, 7:21 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Soy Isoflavones For Inner City Infants At Risk For Asthma (SIRA) Study

NCT05667701
View directory record Official record
Conditions
Wheezing, Asthma in Children
Interventions
Soy isoflavone, matching placebo
Drug
Lead sponsor
Rajesh Kumar
Other
Eligibility
2 Months to 12 Months
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 21, 2025 · Synced Oct 21, 2026, 7:21 PM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Genes, Soy Isoflavones, and Virus

NCT07828405
View directory record Official record
Conditions
Wheezing
Interventions
Soy Isoflavone Nutritional Supplements
Drug
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
4 Months to 24 Months
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 21, 2026, 7:21 PM EDT
Completed Phase 3 Interventional Results available

Acetaminophen Versus Ibuprofen in Children With Asthma

NCT01606319
View directory record Official record
Conditions
Asthma, Wheezing
Interventions
Acetaminophen, Ibuprofen
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
12 Months to 59 Months
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
15
States / cities
Tucson, Arizona • Oakland, California • San Francisco, California + 10 more
Source: ClinicalTrials.gov public record
Updated Jan 16, 2017 · Synced Oct 21, 2026, 7:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study of Hypertonic Saline for Infants Hospitalized With Bronchiolitis

NCT01488448
View directory record Official record
Conditions
Bronchiolitis
Interventions
3% sodium chloride, 0.9% sodium chloride
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
Up to 12 Months
Enrollment
227 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 2, 2017 · Synced Oct 21, 2026, 7:21 PM EDT
Completed Not applicable Interventional

Fever and Wheezing Events in Children After US Influenza Vaccines Using Text Messaging

NCT02295007
View directory record Official record
Conditions
Fever, Wheezing
Interventions
text message
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
2 Years to 11 Years
Enrollment
266 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
3
States / cities
Atlanta, Georgia • Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated May 12, 2016 · Synced Oct 21, 2026, 7:21 PM EDT
Terminated Phase 1Phase 2 Interventional

Randomized, Placebo/Active Crossover Dose-ranging Study for Safety and Efficacy in Asthma Patients.

NCT01025648
View directory record Official record
Conditions
Asthma
Interventions
E004 (epinephrine inhalation aerosol), 90 mcg/actuation, E004 Placebo, E004 (epinephrine inhalation aerosol), 125 mcg, E004 (epinephrine inhalation aerosol), 220 mcg, epinephrine inhalation aerosol, CFC propelled, E004 (epinephrine inhalation aerosol), 160 mcg
Drug
Lead sponsor
Amphastar Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
2
States / cities
San Jose, California • Stockton, California
Source: ClinicalTrials.gov public record
Updated May 16, 2018 · Synced Oct 21, 2026, 7:21 PM EDT
Completed Phase 3 Interventional Results available

CARE Network Maintenance Versus Intermittent Inhaled Steroids in Wheezing Toddlers (MIST)

NCT00675584
View directory record Official record
Conditions
Asthma
Interventions
Budesonide, Placebo Budesonide
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
12 Months to 53 Months
Enrollment
278 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
5
States / cities
Tucson, Arizona • San Diego, California • Denver, Colorado + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2018 · Synced Oct 21, 2026, 7:21 PM EDT
Completed Not applicable Interventional

Pediatric Emergency Department Decision Support System to Reduce Secondhand Smoke

NCT02489708
View directory record Official record
Conditions
Asthma, Smoking Cessation
Interventions
Cessation Counseling
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Day and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 9, 2021 · Synced Oct 21, 2026, 7:21 PM EDT
Not listed No phase listed Observational

Wheezometer™ Exploratory (WM) Field Study

NCT01156818
View directory record Official record
Conditions
Respiratory Sounds, Wheezing
Interventions
Not listed
Lead sponsor
KarmelSonix Ltd.
Industry
Eligibility
8 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 9, 2011 · Synced Oct 21, 2026, 7:21 PM EDT
Completed Phase 3 Interventional Results available

Individualized Therapy For Asthma in Toddlers

NCT01606306
View directory record Official record
Conditions
Asthma, Wheezing
Interventions
daily fluticasone propionate, Montelukast, as-needed fluticasone propionate
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
12 Months to 59 Months
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
13
States / cities
Tucson, Arizona • Oakland, California • San Francisco, California + 9 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2017 · Synced Oct 21, 2026, 7:21 PM EDT
Not listed No phase listed Observational

Waveform and Spectral Characteristics of Perioperative Wheezing

NCT04873882
View directory record Official record
Conditions
Respiratory Sounds, Thoracic Surgery
Interventions
Acoustic ventilation
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 5, 2021 · Synced Oct 21, 2026, 7:21 PM EDT
Terminated Phase 2 Interventional Results available

Pilot Study of Pioglitazone for the Treatment of Moderate to Severe Asthma in Obese Asthmatics (Glitz Asthma)

NCT00787644
View directory record Official record
Conditions
Asthma, Obesity
Interventions
Pioglitazone, Placebo
Drug
Lead sponsor
University of Vermont
Other
Eligibility
18 Years to 60 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Colchester, Vermont
Source: ClinicalTrials.gov public record
Updated Feb 26, 2015 · Synced Oct 21, 2026, 7:21 PM EDT