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Showing 1–24 of 39 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Worry Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Tranquil Moments II-CBT vs. Yoga for Worry

NCT02968238
View directory record Official record
Conditions
Anxiety
Interventions
Cognitive-behavioral therapy, Yoga
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Jul 21, 2026, 11:30 AM EDT
Recruiting Phase 2 Interventional

Sleep to Reduce Incident Depression Effectively in Peripartum

NCT06430333
View directory record Official record
Conditions
Insomnia, Depression
Interventions
Perinatal Understanding of Mindful Awareness for Sleep (PUMAS), Treatment-as-usual (TAU)
Behavioral · Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Jul 21, 2026, 11:30 AM EDT
Completed Not applicable Interventional Results available

Improving Attentional and Cognitive Control in the Psychological Treatment of Intrusive Thoughts

NCT04225624
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Major Depressive Disorder
Interventions
Emotion Regulation Therapy - Attention Regulation (AR-ERT), Supportive Psychotherapy (SPT)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Jul 21, 2026, 11:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Views on Cancer Prevention and Daily Lifestyle

NCT03575117
View directory record Official record
Conditions
Colorectal Cancer, Sedentary Lifestyle
Interventions
Common-Sense Model (CSM) Be Well, ACS usual messages, NCI HealthyYouTXT--Get Active (HYT--GA)
Behavioral
Lead sponsor
University of California, Merced
Other
Eligibility
18 Years to 65 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Merced, California
Source: ClinicalTrials.gov public record
Updated Nov 2, 2022 · Synced Jul 21, 2026, 11:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Veteran Caregiver Reducing Stress Time (VetCareReST) Study

NCT02852174
View directory record Official record
Conditions
Stress, Depression, Anxiety and Worry
Interventions
Mindfulness meditation training
Behavioral
Lead sponsor
Sandraluz Lara-Cinisomo
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Champaign, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 30, 2018 · Synced Jul 21, 2026, 11:30 AM EDT
Recruiting Not applicable Interventional

Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors

NCT06538246
View directory record Official record
Conditions
Depression, Anxiety, Post-traumatic Stress Disorder, Stress, Worries; Pain or Disability, Breath Shortness
Interventions
Blueprint, Education program
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Jul 21, 2026, 11:30 AM EDT
Recruiting Not applicable Interventional

Readiness and Progress in Emotion Regulation Therapy

NCT07478393
View directory record Official record
Conditions
Rumination, Worry, Self-Criticism, Anxiety, Depression, Distress, Emotional
Interventions
Emotion Regulation Therapy via Telehealth
Behavioral
Lead sponsor
Teachers College, Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Jul 21, 2026, 11:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dimensional Brain Behavior Predictors of CBT Outcomes in Pediatric Anxiety

NCT02810171
View directory record Official record
Conditions
Anxiety Disorders, Social Anxiety Disorder, Social Phobia, Generalized Anxiety Disorder, Separation Anxiety Disorder, Specific Phobia, Phobia, Agoraphobia, Panic Disorder, Panic Attack, Anxiety
Interventions
Cognitive Behavioral Therapy, Relaxation Therapy
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
7 Years to 17 Years
Enrollment
207 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 19, 2021 · Synced Jul 21, 2026, 11:30 AM EDT
Recruiting Not applicable Interventional

Brief Interventions for Coping with Distress

NCT05779761
View directory record Official record
Conditions
Distress, Emotional, Emotional Dysfunction, Anxiety, Depression
Interventions
Online, Self-Directed Attention Skills Training with Coaching Support, Online, Self-Directed Attention & Reflective Thought Skills Training with Coaching Support, Online, Self-Directed Health & Wellness Education Training with Coaching Support
Behavioral
Lead sponsor
Teachers College, Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 20, 2024 · Synced Jul 21, 2026, 11:30 AM EDT
Withdrawn Not applicable Interventional

Worry Exposure for Generalized Anxiety Disorder

NCT02382224
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
Worry Exposure for GAD, 12-week Waitlist
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 23, 2018 · Synced Jul 21, 2026, 11:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Mindfulness Approach to UA for Afro-descendants

NCT05881681
View directory record Official record
Conditions
Anxiety, Stress
Interventions
App-Delivered Mindfulness Training (MT)
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 14, 2024 · Synced Jul 21, 2026, 11:30 AM EDT
Recruiting Not applicable Interventional

Text Message Safety Behavior Fading for Pathological Worry

NCT07391020
View directory record Official record
Conditions
Generalized Anxiety Disorder (GAD), Worrying, Anxiety
Interventions
Safety Behavior Fading for Pathological Worry, Progressive Muscle Relaxation (PMR)
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Jul 21, 2026, 11:30 AM EDT
Completed Not applicable Interventional

Assessment of the Efficacy of Digital CBT for Anxiety in Adults With Chronic Musculoskeletal Pain

NCT04907656
View directory record Official record
Conditions
Pain, Chronic, Pain, Musculoskeletal, Anxiety
Interventions
dCBT
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2023 · Synced Jul 21, 2026, 11:30 AM EDT
Recruiting Not applicable Interventional

ERP to Improve Functioning in Veterans With OCD

NCT05240924
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD), Comorbid Post-Traumatic Stress Disorder and OCD
Interventions
Exposure and Response Prevention, Stress Management Training
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
18
States / cities
East Orange, New Jersey • Buffalo, New York • New York, New York + 15 more
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Jul 21, 2026, 11:30 AM EDT
Completed Not applicable Interventional

Cognitive-Behavioral Intervention for Worry, Uncertainty, and Insomnia for Cancer Survivors

NCT01929720
View directory record Official record
Conditions
Anxiety Disorder, Worry, Uncertainty, Sleep Disorders, Insomnia, Fatigue, Pain, Depression, Cognitive-behavioral Therapy, Psychological Intervention, Esophageal Cancer, Pancreatic Cancer, Leukemia, Lung Cancer, Multiple Myeloma, Ovarian Neoplasm, Stage III or IV Cervical or Uterine Cancer, Stage IIIB, IIIC, or IV Breast Cancer, Glioblastoma Multiforme, Relapsed Lymphoma, Stage III or IV Colorectal Cancer, Stage IIIC or IV Melanoma
Interventions
Cognitive-behavioral therapy for worry, uncertainty & insomnia
Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Jul 21, 2026, 11:30 AM EDT
Terminated No phase listed Observational

Exploring The Role Of Palliative Care In Phase 1 Enrolled Pediatric Oncology Patients

NCT05412563
View directory record Official record
Conditions
Quality of Life
Interventions
Not listed
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years and older
Enrollment
31 participants
Timeline
2022 – 2025
U.S. locations
2
States / cities
Bethesda, Maryland • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 20, 2025 · Synced Jul 21, 2026, 11:30 AM EDT
Active, not recruiting No phase listed Observational

Evaluating the Effects of Genetic Testing on Patients' Stress Levels

NCT02783664
View directory record Official record
Conditions
Breast Cancer
Interventions
Questionnaires to Evaluate Anxiety Related to Genetic Testing
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older · Female only
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Jul 21, 2026, 11:30 AM EDT
Completed Not applicable Interventional

Wonders & Worries: A Clinical Trial of a Psychosocial Intervention for Children Who Have a Parent With Cancer

NCT02758639
View directory record Official record
Conditions
Cancer, Psychological Adjustment
Interventions
Wonders & Worries Psychosocial Intervention
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
5 Years to 14 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 9, 2018 · Synced Jul 21, 2026, 11:30 AM EDT
Not listed Not applicable Interventional

An Idiographic Examination of Treatment Mechanisms in Emotion Regulation Therapy

NCT05590741
View directory record Official record
Conditions
Rumination, Worry, Self-Criticism, Anxiety, Depression, Distress, Emotional
Interventions
Emotion Regulation Therapy via Telehealth
Behavioral
Lead sponsor
Teachers College, Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 3, 2024 · Synced Jul 21, 2026, 11:30 AM EDT
Completed Not applicable Interventional Results available

Calmer Life: Treating Worry Among Older Adults In Underserved, Low-income, Minority Communities

NCT02391363
View directory record Official record
Conditions
Anxiety
Interventions
Cognitive behavior treatment, Information and referral
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
50 Years and older
Enrollment
247 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 30, 2019 · Synced Jul 21, 2026, 11:30 AM EDT
Completed Not applicable Interventional Results available

A Pilot fMRI Study of TMS in Late-Life Severe Worry

NCT03577106
View directory record Official record
Conditions
Anxiety Disorders Generalized
Interventions
Transcranial magnetic stimulation (TMS)
Device
Lead sponsor
Carmen Andreescu
Other
Eligibility
50 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Jul 21, 2026, 11:30 AM EDT
Not yet recruiting Not applicable Interventional

Calming Minds Study

NCT07577401
View directory record Official record
Conditions
Anxiety, Anxiety Depression, Worry, Depression, Rumination - Thoughts
Interventions
Be Specific, Be Kind, Be Present, Break Habit, Psychoeducation
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Imperial, California
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Jul 21, 2026, 11:30 AM EDT
Enrolling by invitation No phase listed Observational

Integrating eSAGE With EHR Data Using Machine Learning for the Early Detection and Monitoring of Cognitive Impairment in Individuals

NCT06017505
View directory record Official record
Conditions
Dementia, Alzheimer Disease, Mild Cognitive Impairment, Worried Well
Interventions
electronic self administered gerocognitive examination (eSAGE)
Diagnostic Test
Lead sponsor
Douglas Scharre
Other
Eligibility
50 Years and older
Enrollment
1,486 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Jul 21, 2026, 11:30 AM EDT
Completed Not applicable Interventional

Calmer Life: A Worry Reduction Program for Older Adults

NCT00932178
View directory record Official record
Conditions
Anxiety
Interventions
Calmer Life
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
50 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced Jul 21, 2026, 11:30 AM EDT