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ClinicalTrials.gov public records Last synced Oct 21, 2026, 2:10 AM EDT

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Showing 1–24 of 39 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Worry Clear all
Completed Not applicable Interventional Results available

A Pilot fMRI Study of TMS in Late-Life Severe Worry

NCT03577106
View directory record Official record
Conditions
Anxiety Disorders Generalized
Interventions
Transcranial magnetic stimulation (TMS)
Device
Lead sponsor
Carmen Andreescu
Other
Eligibility
50 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 21, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mellowing Mind: Comparing Two Technology Based Mindfulness Interventions for Stress Impacted by COVID-19 in Underserved Communities

NCT05180513
View directory record Official record
Conditions
Worry, Stress
Interventions
Teleconference Mindfulness Intervention, Smartphone App Mindfulness Intervention
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Sep 20, 2024 · Synced Oct 21, 2026, 2:10 AM EDT
Recruiting Not applicable Interventional

Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors

NCT06538246
View directory record Official record
Conditions
Depression, Anxiety, Post-traumatic Stress Disorder, Stress, Worries; Pain or Disability, Breath Shortness
Interventions
Blueprint, Education program
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 21, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Role of Cognitive Control in the Transdiagnostic Conceptualization of "Intrusive Thoughts"

NCT03414619
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Major Depressive Disorder
Interventions
Cognitive Control Tasks and Script Driven Imagery
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Oct 21, 2026, 2:10 AM EDT
Recruiting Not applicable Interventional

Readiness and Progress in Emotion Regulation Therapy

NCT07478393
View directory record Official record
Conditions
Rumination, Worry, Self-Criticism, Anxiety, Depression, Distress, Emotional
Interventions
Emotion Regulation Therapy via Telehealth
Behavioral
Lead sponsor
Teachers College, Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 21, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Tranquil Moments II-CBT vs. Yoga for Worry

NCT02968238
View directory record Official record
Conditions
Anxiety
Interventions
Cognitive-behavioral therapy, Yoga
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 12, 2020 · Synced Oct 21, 2026, 2:10 AM EDT
Recruiting Phase 2 Interventional

Sleep to Reduce Incident Depression Effectively in Peripartum

NCT06430333
View directory record Official record
Conditions
Insomnia, Depression
Interventions
Perinatal Understanding of Mindful Awareness for Sleep (PUMAS), Treatment-as-usual (TAU)
Behavioral · Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 21, 2026, 2:10 AM EDT
Completed Not applicable Interventional

Emotion Regulation Therapy for Clinical Worry and Rumination

NCT04060940
View directory record Official record
Conditions
Anxiety Disorders and Symptoms, Depression, Anxiety, Generalized Anxiety Disorder, Emotional Dysfunction
Interventions
Emotion Regulation Therapy: 8-session version, Emotion Regulation Therapy: 16-session version
Behavioral
Lead sponsor
Douglas Mennin
Other
Eligibility
18 Years to 29 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 17, 2022 · Synced Oct 21, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Targeting Worry to Improve Sleep

NCT03684057
View directory record Official record
Conditions
Anxiety, Sleep Disturbance
Interventions
App-Delivered Mindfulness Training (MT)
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 10, 2022 · Synced Oct 21, 2026, 2:10 AM EDT
Completed Not applicable Interventional Results available

Improving Attentional and Cognitive Control in the Psychological Treatment of Intrusive Thoughts

NCT04225624
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Major Depressive Disorder
Interventions
Emotion Regulation Therapy - Attention Regulation (AR-ERT), Supportive Psychotherapy (SPT)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Oct 21, 2026, 2:10 AM EDT
Completed Not applicable Interventional

Study to Identify if OVR Health's VR-Kit is Safe to Use and Helps to Improve Focus, Attention and Reduce Worry & Rumination.

NCT05291429
View directory record Official record
Conditions
Anxiety, Depression, Anxiety
Interventions
OVR Health's VR experience
Device
Lead sponsor
Oxford VR
Industry
Eligibility
18 Years to 79 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Mar 22, 2022 · Synced Oct 21, 2026, 2:10 AM EDT
Not listed Not applicable Interventional

An Idiographic Examination of Treatment Mechanisms in Emotion Regulation Therapy

NCT05590741
View directory record Official record
Conditions
Rumination, Worry, Self-Criticism, Anxiety, Depression, Distress, Emotional
Interventions
Emotion Regulation Therapy via Telehealth
Behavioral
Lead sponsor
Teachers College, Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 4, 2024 · Synced Oct 21, 2026, 2:10 AM EDT
Completed Not applicable Interventional

SkillJoy Clinical Trial

NCT05040061
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
SkillJoy Intervention, Active Self-Monitoring Control Intervention
Behavioral
Lead sponsor
Skidmore College
Other
Eligibility
18 Years and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Saratoga Springs, New York
Source: ClinicalTrials.gov public record
Updated Sep 10, 2021 · Synced Oct 21, 2026, 2:10 AM EDT
Completed Not applicable Interventional

Assessment of the Efficacy of Digital CBT for Anxiety in Adults With Chronic Musculoskeletal Pain

NCT04907656
View directory record Official record
Conditions
Pain, Chronic, Pain, Musculoskeletal, Anxiety
Interventions
dCBT
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 21, 2023 · Synced Oct 21, 2026, 2:10 AM EDT
Withdrawn Not applicable Interventional

Worry Exposure for Generalized Anxiety Disorder

NCT02382224
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
Worry Exposure for GAD, 12-week Waitlist
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 24, 2018 · Synced Oct 21, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Progressive Goal Attainment Program for Veterans

NCT01565863
View directory record Official record
Conditions
Mental Disorders, Worries; Pain or Disability
Interventions
Progressive Goal Attainment Program
Behavioral
Lead sponsor
MDRC
Other
Eligibility
18 Years to 55 Years
Enrollment
199 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
2
States / cities
West Haven, Connecticut • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2020 · Synced Oct 21, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Veteran Caregiver Reducing Stress Time (VetCareReST) Study

NCT02852174
View directory record Official record
Conditions
Stress, Depression, Anxiety and Worry
Interventions
Mindfulness meditation training
Behavioral
Lead sponsor
Sandraluz Lara-Cinisomo
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Champaign, Illinois
Source: ClinicalTrials.gov public record
Updated May 1, 2018 · Synced Oct 21, 2026, 2:10 AM EDT
Active, not recruiting Not applicable Interventional

Text Message Safety Behavior Fading for Pathological Worry

NCT07391020
View directory record Official record
Conditions
Generalized Anxiety Disorder (GAD), Worrying, Anxiety
Interventions
Safety Behavior Fading for Pathological Worry, Progressive Muscle Relaxation (PMR)
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 21, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dimensional Brain Behavior Predictors of CBT Outcomes in Pediatric Anxiety

NCT02810171
View directory record Official record
Conditions
Anxiety Disorders, Social Anxiety Disorder, Social Phobia, Generalized Anxiety Disorder, Separation Anxiety Disorder, Specific Phobia, Phobia, Agoraphobia, Panic Disorder, Panic Attack, Anxiety
Interventions
Cognitive Behavioral Therapy, Relaxation Therapy
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
7 Years to 17 Years
Enrollment
207 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 20, 2021 · Synced Oct 21, 2026, 2:10 AM EDT
Terminated No phase listed Observational

Exploring The Role Of Palliative Care In Phase 1 Enrolled Pediatric Oncology Patients

NCT05412563
View directory record Official record
Conditions
Quality of Life
Interventions
Not listed
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years and older
Enrollment
31 participants
Timeline
2022 – 2025
U.S. locations
2
States / cities
Bethesda, Maryland • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 21, 2025 · Synced Oct 21, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Mindfulness Approach to UA for Afro-descendants

NCT05881681
View directory record Official record
Conditions
Anxiety, Stress
Interventions
App-Delivered Mindfulness Training (MT)
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 15, 2024 · Synced Oct 21, 2026, 2:10 AM EDT
Completed Not applicable Interventional Results available

Calmer Life: Treating Worry Among Older Adults In Underserved, Low-income, Minority Communities

NCT02391363
View directory record Official record
Conditions
Anxiety
Interventions
Cognitive behavior treatment, Information and referral
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
50 Years and older
Enrollment
247 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 31, 2019 · Synced Oct 21, 2026, 2:10 AM EDT
Completed Not applicable Interventional

School-based Treatment of Anxiety Research Study (STARS)

NCT01761396
View directory record Official record
Conditions
Anxiety Disorders
Interventions
CBT, UC
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
6 Years to 18 Years
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced Oct 21, 2026, 2:10 AM EDT
Recruiting Not applicable Interventional

ERP to Improve Functioning in Veterans With OCD

NCT05240924
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD), Comorbid Post-Traumatic Stress Disorder and OCD
Interventions
Exposure and Response Prevention, Stress Management Training
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
18
States / cities
East Orange, New Jersey • Buffalo, New York • New York, New York + 15 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 21, 2026, 2:10 AM EDT