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Conditions: Mucus Obstruction, Intubation
Interventions: mucomyst, sodium chloride (saline); Drug
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years and older
Enrollment: 260 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Anxiety Disorders, Stress Disorders, Post-Traumatic, Pregnancy, High Risk, Depressive Disorder, Major, Pregnancy Complications, ADHD - Attention Deficit Disorder With Hyperactivity
Interventions: Collaborative Mental Health Care Program (CMHCP); Behavioral
Lead sponsor: Indiana University; Other
Eligibility: 18 Years to 100 Years · Female only
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Lung Diseases, Medication Compliance
Interventions: Fluticasone propionate 230mcg for 3 Months, Current Treatment or no treatment, Salmeterol 21mcg for 3 Months; Drug
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: New York, New York

Conditions: Psychological Trauma
Interventions: The Developmental Interaction Workshop Series (DIWS); Behavioral
Lead sponsor: Cornell University; Other
Eligibility: 8 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Ithaca, New York

Conditions: Diabetic Foot, Diabetic Foot Ulcer, Wound; Foot, Wound Leg, Wound Heal, Diabetes Complications
Interventions: Remote wound monitoring technology; Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 148 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Malignant Head and Neck Neoplasm, Mucositis, Radiation-Induced Disorder
Interventions: Educational Intervention, Gabapentin, Pain Therapy, Quality-of-Life Assessment, Questionnaire Administration, Oxycodone/Acetaminophen, Hydrocodone/Acetaminophen, Fentanyl, Ibuprofen, Magic Mouthwash; Other · Drug
Lead sponsor: Vanderbilt-Ingram Cancer Center; Other
Eligibility: 21 Years and older
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Acquired Brain Injury, Mental Health, Depressive Symptoms, Anxiety Symptoms, Loneliness
Interventions: Multifaceted implementation program; Behavioral
Lead sponsor: Colorado State University; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Denver, Colorado • Fort Collins, Colorado

Conditions: Diabetic Foot, Chronic Foot Ulcer, Wound Healing, Foot Ulcer
Interventions: SynPath Acellular Dermal Matrix plus Off-loading Device, Wound Dressing composed of 90% collagen and 10% Alginate plus Off-loading Device; Device
Lead sponsor: PolyNovo Biomaterials Pty Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 7
States / cities: Castro Valley, California • Fresno, California • Vista, California + 4 more

Conditions: Knee Injuries, Joint Surface Knee Lesions
Interventions: Marketed Product - MP01, Surgical Standard of Care; Device · Procedure
Lead sponsor: Smith & Nephew, Inc.; Industry
Eligibility: 21 Years to 75 Years
Enrollment: 170 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: La Mesa, California

Conditions: Spasticity as Sequela of Stroke, Spastic Cerebral Palsy, Spasticity, Muscle
Interventions: stereotactic radiosurgery (SRS) dorsal root rhizotomy radiomodulation, Sham; Radiation · Other
Lead sponsor: Ohio State University; Other
Eligibility: 16 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Winter Park, Florida • Columbus, Ohio

Conditions: Hip Fractures, Myocardial Injury
Interventions: Accelerated medical clearance and surgery; Other
Lead sponsor: Population Health Research Institute; Other
Eligibility: 45 Years and older
Enrollment: 1,100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 19
States / cities: Chandler, Arizona • Davis, California • New Haven, Connecticut + 15 more

Conditions: Mental Health, Stress Disorders, Post-Traumatic, Substance-Related Disorders, Tobacco Use Disorder
Interventions: Integrated Care for Smoking Cessation in PTSD patients, Standard of Care; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years to 80 Years
Enrollment: 943 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2009
U.S. locations: 11
States / cities: Tuscaloosa, Alabama • San Diego, California • Washington D.C., District of Columbia + 8 more

Conditions: Burns, Ascorbic Acid Deficiency, Burn Shock, Burn Degree Second, Burn Degree Third, Fluid and Electrolyte Imbalance
Interventions: Vitamin C; Dietary Supplement
Lead sponsor: Arrowhead Regional Medical Center; Other
Eligibility: Not listed
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Colton, California

Conditions: Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia, Asparagine Synthetase Deficiency, CHARGE Syndrome, Early Infantile Epileptic Encephalopathy, FOXG1 Syndrome, KBG Syndrome, Noonan Syndrome, Severe Hemophilia A, Short Bowel Syndrome, Beta-Propeller Protein-Associated Neurodegeneration, Brain Injury of Prematurity With Periventricular Leukomalacia, Chromosome 17p13.3 Microdeletion Syndrome, Chromosome 1q43-1q44 Deletion, Cockayne Syndrome, Congenital Diaphragmatic Hernia, End-Stage Renal Disease With Cloacal Anomaly, Mitochondrial Depletion Disorder, Severe Factor VII Deficiency
Interventions: Family Centered pediatric palliative care for family caregivers of children with rare diseases.; Behavioral
Lead sponsor: Children's National Research Institute; Other
Eligibility: 12 Months to 99 Years
Enrollment: 480 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Depression, PTSD
Interventions: Usual Care, Modified Behavioral Activation (Task Sharing); Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Hardin, Montana

Conditions: Wound Care, Pressure Ulcer, Venous Ulcer, Surgical Wound, Trauma Wounds, Draining Wound
Interventions: Integra Dermal Regeneration template (IDRT); Device
Lead sponsor: Joshua Choo; Other
Eligibility: 55 Years to 100 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Neuropathic Diabetic Ulcer - Foot
Interventions: RedDress Wound Care System (RD1); Device
Lead sponsor: RedDress Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 4
States / cities: Miami, Florida • North Miami Beach, Florida • Pittsburgh, Pennsylvania + 1 more

Conditions: Lacerations, Wounds, Injuries
Interventions: Absorbable Suture Arm, Non-absorbable suture (Prolene), suture; Procedure · Device
Lead sponsor: Temple University; Other
Eligibility: 1 Year to 65 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Burns, Trauma
Interventions: Continuous Glucose Monitoring; Device
Lead sponsor: United States Army Institute of Surgical Research; Federal
Eligibility: 18 Years to 72 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2013
U.S. locations: 1
States / cities: Fort Sam Houston, Texas

Conditions: Wounds and Injuries
Interventions: Altrazeal (R) Transforming Powder Dressing, Standard of Care burn dressing; Device · Other
Lead sponsor: ULURU Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 6
States / cities: Orange, California • Washington D.C., District of Columbia • Miami, Florida + 3 more

Conditions: Rotator Cuff Tear
Interventions: Breg Polar Care Wave Cold Compression Device; Device
Lead sponsor: University of Nevada, Reno; Other
Eligibility: 18 Years to 70 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Mammoth Lakes, California • Taos, New Mexico

Conditions: Pressure Ulcers
Interventions: Leptospermum scoparium honey, Standard of Care Treatment; Other
Lead sponsor: New York City Health and Hospitals Corporation; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Brain Injury Traumatic Mild, Brain Injuries, Brain Injuries, Acute, Head Injury With Intracranial Hemorrhage, Head Injury Trauma, Brain Injury Traumatic Focal With Loss of Consciousness, Skull Fractures, Diffuse Axonal Injury, Intracranial Hemorrhages, Head Injury
Interventions: Validated Questionnaires, Questionnaires, Clinician / Medical Record Variables; Behavioral · Other
Lead sponsor: University of California, Davis; Other
Eligibility: 11 Years to 17 Years
Enrollment: 2,592 participants
Timeline: 2024 – 2028
U.S. locations: 6
States / cities: Sacramento, California • Philadelphia, Pennsylvania • Providence, Rhode Island + 3 more

Conditions: Chronic Pressure Ulcers
Interventions: PuraPly® Antimicrobial Wound Matrix, SOC for Pressure Ulcers; Device · Other
Lead sponsor: Organogenesis; Industry
Eligibility: 18 Years to 99 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 2
States / cities: Lake Success, New York • Mineola, New York

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Comparison of Different Mucoactive Agents for the Care of the Intubated Patient in a Surgical Trauma Intensive Care Unit

MOCHA: Embedded Inpatient Mental Health Care for High-Risk Perinatal Patients

Uncontrolled Lower Respiratory Symptoms in the WTC Survivor Program

Facilitating Developmental Interactions With Children in Out-of-Home Care

Feasibility and Effectiveness of a Remote Monitoring Program for the Treatment of Diabetic Foot Ulcers

Gabapentin Compared to Standard of Care in Preventing Mucositis in Patients With Stage III-IV Head and Neck Cancer Undergoing Primary or Adjuvant Chemoradiation Therapy

Occupational Therapy for Mental Health and Engagement in Neurorehabilitation

Randomized Clinical Study Comparing SynPath to Standard of Care in Treatment of Chronic Diabetic Foot Ulcers

A Post Approval Multicenter 10 Year Follow-up Observational Trial of Marketed Product - MP01 vs. Surgical Standard of Care (SSOC) Used for the Treatment of Joint Surface Lesions of the Knee

Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy

HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 Trial

Integrating Clinical Practice Guidelines for Smoking Cessation Into Mental Health Care for Veterans With Posttraumatic Stress Disorder

Low Dose Vitamin C in Burns >20% Compared to Previous Studies With High Dose Vitamin C

Palliative Care Needs of Children With Rare Diseases and Their Families

DDBT Adapted Problem Solving Treatment for Primary Care

Direct Application of Integra Bilayer Matrices on Bare Calvarium Without Preliminary Burring

Safety Trial of the RedDress Wound Care System (RD1) in Management of Texas 1a or 2a Neuropathic Diabetic Foot Ulcers.

Comparison of Cosmetic Outcomes of Lacerations Repaired Using Absorbable Versus Non-absorbable Sutures

Continuous Glucose Monitoring (POC) in the ICU

Acute Partial Thickness Burn Study Comparing Transforming Powder Dressing to Standard of Care Dressing

Clinical Research Study of the Benefits of BREG Polar Care Wave to Reduce Opioid Use by Patients Having Undergone Arthroscopic Rotator Cuff Repair Shoulder Surgery

Leptospermum Scoparium Honey and Wound Care for Pressure Ulcers

Screening Emotions in Adolescents at the Hospital for mTBI

PuraPly® AM Plus the Standard of Care to Standard of Care Alone for the Management of Stage II-IV Pressure Ulcers.