Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 5, 2026, 4:58 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 1,038 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Wound Leg Clear all

Conditions: Leg Ulcers
Interventions: Bioengineered skin; Device
Lead sponsor: Roger Williams Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2005
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Knee Pain, Hip Pain, Ankle Pain, Lumbopelvic Pain
Interventions: lumbosacral joint manipulation, lumbar passive range of motion, No active intervention; Other
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 50 Years
Enrollment: 106 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Hallux Limitus
Interventions: standard of care, Metarsal Dynasplint; Other · Device
Lead sponsor: Dynasplint Systems, Inc.; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2012
U.S. locations: 3
States / cities: Boston, Massachusetts • Henderson, Nevada • Houston, Texas

Conditions: Diabetic Foot Ulcer (DFU), Chronic Foot Ulcers
Interventions: Allograft; Other
Lead sponsor: Tides Medical; Industry
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 9
States / cities: Fresno, California • Los Angeles, California • Vista, California + 5 more

Conditions: Patellofemoral Joint Dislocation, Bicep Tendon Rupture
Interventions: Blood Flow Restriction (BFR) Therapy, Physical Therapy; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Pelvic Fracture
Interventions: Pelvic Binder Radiography; Diagnostic Test
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Weakness, Muscle, Muscle Weakness, Muscle Loss, Muscle Atrophy, Injury, Knee
Interventions: Neuromuscular Electrical Stimulation, Action Observation + Mental Imagery; Other
Lead sponsor: University of Central Florida; Other
Eligibility: 18 Years to 40 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Bone Cement Implantation Syndrome
Interventions: Administration of general anaesthesia, Neuraxial Analgesia; Procedure
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2027 – 2028
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Tibial Fractures
Interventions: micromotion intramedullary nail cohort, standard intramedullary nail cohort; Procedure
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 85 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Diabetic Foot Ulcers
Interventions: Not listed
Lead sponsor: HyperMed; Industry
Eligibility: 21 Years to 85 Years
Enrollment: 256 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 3
States / cities: Sylmar, California • Cleveland, Ohio • Philadelphia, Pennsylvania

Conditions: Complex Diabetic Foot Wounds
Interventions: Grafix®; Other
Lead sponsor: Osiris Therapeutics; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2014
U.S. locations: 4
States / cities: Phoenix, Arizona • Tucson, Arizona • Miami, Florida + 1 more

Conditions: Diabetic Foot Ulcer
Interventions: PEP (Purified Exosome Product) / TISSEEL; Biological
Lead sponsor: Rion Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Blue Ash, Ohio

Conditions: Wounds, Leg Ulcers, Pressure Ulcers, Diabetic Foot Ulcers
Interventions: AutoloGel System; Device
Lead sponsor: Cytomedix; Industry
Eligibility: 18 Years to 95 Years
Enrollment: 131 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2012
U.S. locations: 2
States / cities: Augusta, Georgia • El Paso, Texas

Conditions: Acute and Chronic Wounds, Pressure Ulcers, Trauma Wounds, Diabetic Foot Ulcers, Venous Stasis Ulcers
Interventions: SNaP Wound Care System; Device
Lead sponsor: 3M; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 2
States / cities: Daly City, California

Conditions: Anterior Cruciate Ligament Rupture
Interventions: Blood Flow Restriction using Delfi Personalized Tourniquet System; Device
Lead sponsor: Children's Healthcare of Atlanta; Other
Eligibility: 12 Years to 18 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Pain, Postoperative, Anterior Cruciate Ligament Injury
Interventions: Adductor Canal perineural catheter placement, Femoral Nerve perineural catheter placement, Nimbus pump (Infutronix); Procedure · Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Stanford, California

Conditions: Lower Limb or Combined Lower Limb and Upper Limb Spasticity Due to Stroke or Traumatic Brain Injury
Interventions: NT 201, Placebo; Drug
Lead sponsor: Merz Pharmaceuticals GmbH; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 603 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 15
States / cities: Birmingham, Alabama • Little Rock, Arkansas • Downey, California + 11 more

Conditions: Injuries, Patellofemoral Pain Syndrome, Iliotibial Band Syndrome
Interventions: Strength and Coordination Training, Walking; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Knee Osteoarthritis
Interventions: BEST™ HVPC microcurrent electrical stimulation Pro-Sport Ultra® device; Device
Lead sponsor: Avazzia, Inc; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Meniscus; Detachment, Current Injury
Interventions: Standard of Care Rehabilitation, Experimental Strength Training; Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 90 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Diabetic Foot Ulcer, Non-healing Wound, Non-Healing Ulcer of Skin, Venous Leg Ulcer, Venous Ulcer
Interventions: Debritom; Device
Lead sponsor: Stephanie Wu; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: North Chicago, Illinois

Conditions: Diabetic Foot Ulcer Outcome, Quality of Patient Care
Interventions: cellular and tissue based therapy, negative pressure wound therapy, debridement, advanced wound therapy, Nutritional screening, off-loading, Hyperbaric oxygen Therapy; Biological · Device · Procedure + 1 more
Lead sponsor: U.S. Wound Registry; Other
Eligibility: Not listed
Enrollment: 10,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2025
U.S. locations: 1
States / cities: The Woodlands, Texas

Conditions: Surgical Wound Infection
Interventions: Chlorhexidine gluconate (4%), Mupirocin 2% Ointment; Drug
Lead sponsor: The Cooper Health System; Other
Eligibility: 18 Years and older
Enrollment: 848 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2030
U.S. locations: 1
States / cities: Marlton, New Jersey

Conditions: Amputation, Amputation; Traumatic, Limb, Amputation, Traumatic
Interventions: Low cost lower limb prosthetic socket; Device
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years to 95 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Search by objective public record fields.

Bioengineered Skin and Wound Healing

Effects of Lumbosacral Joint Mobilization/Manipulation on Lower Extremity Muscle Neuromuscular Response

Contracture Reduction Following Bunionectomy: a Longitudinal, Controlled Trial

Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers

BFR After Biceps Tendon Repair and MPFLR

Stress Radiography for Pelvic Ring Injuries

Short Term Immobilization of the Lower Limb

Relationship Between Anesthetic Regimen and Bone Cement Implantation Syndrome (BCIS)

Comparison of Healing Measures Tibial Fractures Following Standard Intramedullary Nailing or Micromotion Tibial Intramedullary Nailing

Hyperspectral Imaging to Assess and Predict Diabetic Foot Ulcers

GrafixCORE®: Open-Label Study to Evaluate the Safety and Efficacy of GrafixCORE® for Complex Diabetic Foot Wounds

Phase 2a Multi-Center Prospective, Randomized Trial to Evaluate the Safety & Efficacy of Topical PEP-TISSEEL for Diabetic Foot Ulcers (DFU)

The AutoloGel™ Post-Market Surveillance (TAPS) Program

Clinical Evaluation of the SNaP Wound Care System

BFRT in Adolescents After ACL Reconstruction

Pain Control for Anterior Cruciate Ligament Reconstruction Patients With Adductor Canal or Femoral Perineural Infusions

Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury

Effect of Strength and Coordination Training on Biomechanics and Injury in New Runners

Veteran Affairs Osteoarthritis Knee Study

Effects of Contralateral Strength Training on Postoperative Strength Deficits in the Immobilized Lower Extremity

Debritom - Micro Water Jet Technology and Wound Healing

The Diabetic Foot Ulcer Registry

The Effect of Bacterial Decolonization Before Skin Cancer Surgery on Infection Rate of Lower Extremity Wounds Left Open to Heal

Low Cost Socket for Lower Limb Amputees