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Showing 1–24 of 27 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Wound Vac Clear all
Completed Not applicable Interventional Results available

Vacuum Assisted Closure as a Treatment for Soft Tissue Injuries

NCT00582998
View directory record Official record
Conditions
Fracture of Calcaneus, Pilon or Tibial Plateau
Interventions
Standard Wound Dressing, Vacuum Assisted Closure Device
Procedure · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 24, 2019 · Synced Sep 7, 2026, 10:24 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Incisional Negative Pressure Wound Therapy in High Risk Patients Undergoing Panniculectomy: A Prospective Randomized Controlled Trial

NCT03010137
View directory record Official record
Conditions
Complications Wounds, Negative Pressure Wound Therapy, Wound Healing Delayed, Incisional, Panniculectomy, Incisional Negative Pressure Wound Therapy, Incisional Vac, Wound Vac, Obese, Renal Failure, Kidney Transplant; Complications, Wound Healing Complication
Interventions
Incisional Negative Pressure Wound Therapy, Standard Closure with Skin Glue, PICO (Smith&Nephew), Dermabond
Procedure · Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 8, 2020 · Synced Sep 7, 2026, 10:24 AM EDT
Completed Not applicable Interventional

Vacuum Assisted Closure as a Treatment for Draining Hematomas

NCT00582179
View directory record Official record
Conditions
Draining Hematoma
Interventions
Standard Pressure Dressing, VAC
Procedure · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 30, 2013 · Synced Sep 7, 2026, 10:24 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Effectiveness Study of Santyl Ointment to Treat Pressure Ulcers

NCT01208220
View directory record Official record
Conditions
Pressure Ulcer, Soft Tissue Necrosis Lower Limb
Interventions
Negative Pressure Wound Therapy, Collagenase Ointment
Device · Biological
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
18 Years to 85 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Jul 16, 2014 · Synced Sep 7, 2026, 10:24 AM EDT
Terminated Not applicable Interventional Results available

Surgical Application of Vac Dressings In Obese Patients to Reduce Wound Complications

NCT02461433
View directory record Official record
Conditions
Wound Infection, Surgical, Obesity, Postoperative Complications
Interventions
Prevena, Standard Dressing
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 25, 2019 · Synced Sep 7, 2026, 10:24 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Prospective Observation of Wound Healing With Prevena Incision Management System

NCT01704924
View directory record Official record
Conditions
Scarring
Interventions
Prevena, Standard of Care Dressing
Device · Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jan 18, 2018 · Synced Sep 7, 2026, 10:24 AM EDT
Terminated Not applicable Interventional

Study to Determine the Utility of Wound Vacuum Assisted Closure (VAC) Compared to Conventional Saline Dressing Changes

NCT00121537
View directory record Official record
Conditions
Wounds, Compartment Syndromes
Interventions
Wound Care -Wound Vacuum Assisted Closure (VAC), Wound Care - Wet to Dry Dressing Changes
Device · Procedure
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2015 · Synced Sep 7, 2026, 10:24 AM EDT
Withdrawn Not applicable Interventional

Incisional Wound Vac in Obese Patients

NCT00789659
View directory record Official record
Conditions
Wound Infection, Postoperative Complication
Interventions
Negative pressure dressing
Other
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Feb 9, 2017 · Synced Sep 7, 2026, 10:24 AM EDT
Completed Not applicable Interventional Results available

Evaluating the Ease of Use of a VAC GranuFoam Bridge Dressing on Diabetic Foot Ulcers Receiving VAC Negative Pressure Wound Therapy

NCT00847730
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
V.A.C. Negative Pressure Wound Therapy System
Device
Lead sponsor
KCI USA, Inc
Industry
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
6
States / cities
New Haven, Connecticut • South Miami, Florida • Bethlehem, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Sep 7, 2026, 10:24 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Vacuum Assisted Closure for Cesarean Section

NCT02390401
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
Vacuum-assisted closure, Standard sterile dressing
Device
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
166 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
4
States / cities
Lebanon, New Hampshire • Nashua, New Hampshire
Source: ClinicalTrials.gov public record
Updated May 21, 2018 · Synced Sep 7, 2026, 10:24 AM EDT
Completed Not applicable Interventional Results available

A Pilot RCT of Veraflo With Prontosan vs VAC in Wounds Requiring Operative Debridement

NCT01867580
View directory record Official record
Conditions
Wounds and Injuries
Interventions
V.A.C.Ulta with Prontosan instillation, V.A.C.Ulta without instillation
Device
Lead sponsor
KCI USA, Inc
Industry
Eligibility
18 Years and older
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
7
States / cities
Washington D.C., District of Columbia • Miami, Florida • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 1, 2024 · Synced Sep 7, 2026, 10:24 AM EDT
Completed No phase listed Observational

Nutritional Regulation of Wound Inflammation: Part III

NCT02332993
View directory record Official record
Conditions
Negative Pressure Therapy, Wound, Open Wound, Type II Obese Diabetic, Type II Non-Obese Diabetic
Interventions
FPP
Dietary Supplement
Lead sponsor
Ohio State University
Other
Eligibility
30 Years to 30 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 22, 2019 · Synced Sep 7, 2026, 10:24 AM EDT
Completed Not applicable Interventional Results available

Vacuum Assisted Closure as a Treatment for Open Fractures

NCT00582361
View directory record Official record
Conditions
Orthopaedic Traumatic Open Fractures
Interventions
Standard Wound Dressing, VAC
Procedure · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2010
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 13, 2013 · Synced Sep 7, 2026, 10:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Wound Vac Bandage Comparison After Spinal Fusion

NCT03000010
View directory record Official record
Conditions
Neuromuscular Scoliosis
Interventions
Incisional Wound Vac, Standard Bandage
Device · Other
Lead sponsor
University of Michigan
Other
Eligibility
0 Years to 17 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 27, 2021 · Synced Sep 7, 2026, 10:24 AM EDT
Terminated Not applicable Interventional Results available

VAC Bioburden Wound Care Assessment

NCT04826965
View directory record Official record
Conditions
Upper Extremity Wound, Lower Extremity Wound, Soft Tissue Abscesses, Traumatic Wounds
Interventions
Wound Vac is applied
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Sep 7, 2026, 10:24 AM EDT
Withdrawn Not applicable Interventional

VAC NPWT KCI Dressing Study

NCT01366105
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
V.A.C. by K.C.I.
Device
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 3, 2013 · Synced Sep 7, 2026, 10:24 AM EDT
Withdrawn Not applicable Interventional

Incisional Negative Pressure Dressing on Clean Closed Groin Incisions

NCT02006511
View directory record Official record
Conditions
Complication of Surgical Procedure
Interventions
Incisional Neg Pressure Wound Therapy (Prevena™), Standard of Care wound therapy
Device · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 120 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced Sep 7, 2026, 10:24 AM EDT
Completed Not applicable Interventional

Evaluating Blast-X® in Combination With Negative Pressure Wound Therapy

NCT04265170
View directory record Official record
Conditions
Pressure Ulcer
Interventions
BlastX with negative pressure therapy
Device
Lead sponsor
SerenaGroup, Inc.
Network
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Kittanning, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 13, 2022 · Synced Sep 7, 2026, 10:24 AM EDT
Completed Not applicable Interventional

Wound Vac Polypropylene Suture Pilot Study

NCT02929238
View directory record Official record
Conditions
Wound Vac, Suture
Interventions
Polypropylene Suture Right Side, Polypropylene Suture Left Side
Other
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 12, 2018 · Synced Sep 7, 2026, 10:24 AM EDT
Completed Not applicable Interventional Results available

Role of Vacuum Assisted Closure (VAC) Device in Postoperative Management of Pelvic and Acetabular Fractures

NCT00635479
View directory record Official record
Conditions
Pelvic Fractures, Acetabular Fractures, Hip Fractures
Interventions
VAC device, Gauze dressing
Device · Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 10, 2017 · Synced Sep 7, 2026, 10:24 AM EDT
Completed Not applicable Interventional Results available

Randomized, Controlled Multicenter Trial of Vacuum Assisted Closure Therapy™ in Diabetic Foot Ulcers

NCT00432965
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
Moist Wound Therapy, VAC Therapy
Device
Lead sponsor
KCI USA, Inc
Industry
Eligibility
18 Years and older
Enrollment
335 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
24
States / cities
Phoenix, Arizona • Tucson, Arizona • Castro Valley, California + 17 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Sep 7, 2026, 10:24 AM EDT
Completed Not applicable Interventional Results available

Lidocaine Analgesia For Removal Of Wound Vac Dressings

NCT01126359
View directory record Official record
Conditions
Pain
Interventions
Lidocaine, Placebo-Saline
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 28, 2014 · Synced Sep 7, 2026, 10:24 AM EDT
Completed Not applicable Interventional Results available

V.A.C. VeraFlo™ Instillation Therapy vs V.A.C. Ulta™ Therapy on Biofilm in Chronically Infected Wounds

NCT02009501
View directory record Official record
Conditions
Lower Extremity Wound Infected, Venous Stasis Ulcers
Interventions
VAC VeraFlo with Dakins Instillation, VAC Ulta Therapy
Device
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 26, 2018 · Synced Sep 7, 2026, 10:24 AM EDT
Completed Not applicable Interventional Results available

Prophylactic Application of an Incisional Wound Vac to Prevent Wound Complications in Obese Spine Surgery Patients

NCT02926924
View directory record Official record
Conditions
Spine Surgery, Wounds Vac
Interventions
Wound Vac, Standard Dressing
Device · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Sep 7, 2026, 10:24 AM EDT