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Conditions: Healthy Adults
Interventions: Crucera-SGS, Meriva 500-SF; Dietary Supplement
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Pressure Ulcer, Ulcer, Ulcer, Pressure, Pressure Injury
Interventions: ACApatch™, caregraFT™, Standard of Care; Other
Lead sponsor: Tiger Biosciences, LLC.; Industry
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Monroeville, Pennsylvania

Conditions: Diabetic Foot Ulcer
Interventions: Oasis, Standard; Device · Other
Lead sponsor: Healthpoint; Industry
Eligibility: 18 Years and older
Enrollment: 82 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 16
States / cities: Little Rock, Arkansas • Carlsbad, California • Fair Oaks, California + 12 more

Conditions: Ecchymosis
Interventions: Petrolatum United States Pharmacopeia (USP), Vitamin K and retinol ointment, Arnica ointment, Vitamin K ointment; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 20 Years to 60 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Diabetic Foot, Lower Extremity Wound
Interventions: Matrion, Conventional Care Wound Management; Other
Lead sponsor: LifeNet Health; Industry
Eligibility: 21 Years to 80 Years
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 8
States / cities: Tucson, Arizona • Carmichael, California • Fresno, California + 5 more

Conditions: Pressure Ulcer, Buttock, Pressure Injury, Pressure Ulcer
Interventions: WiSAT System, Passive Feedback, WiSAT System, Active Feedback; Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 2
States / cities: Hines, Illinois • Pittsburgh, Pennsylvania

Conditions: Diabetic Foot Ulcers
Interventions: MEBO Wound Ointment, Standard of Care (sterile saline moistened gauze); Drug · Procedure
Lead sponsor: Skingenix, Inc.; Industry
Eligibility: 18 Years to 79 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 2
States / cities: New Haven, Connecticut • Boston, Massachusetts

Conditions: Hip Osteoarthritis, Rheumatoid Arthritis, Joint Diseases, Avascular Necrosis, Dislocation, Hip, Femoral Neck Fractures, Trochanteric Fractures, Revision Surgeries
Interventions: G7 Dual Mobility with Vivacit-E bearing, G7 Dual Mobility Longevity bearing; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 358 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2037
U.S. locations: 6
States / cities: Little Rock, Arkansas • Denver, Colorado • Jersey City, New Jersey + 3 more

Conditions: Wound Healing
Interventions: TolaSure Topical Gel, Topical Vehicle Gel; Drug
Lead sponsor: BioMendics, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 2
States / cities: Miami, Florida • College Station, Texas

Conditions: Rheumatoid Arthritis, Osteoarthritis Shoulder, Fractures Humerus, Avascular Necrosis, Correction of Functional Deformity, Traumatic Arthritis, Revision of Other Devices if Sufficient Bone Stock Remains, Rotator Cuff Tears
Interventions: Tornier HRS (HUMERAL RECONSTRUCTION SYSTEM) shoulder system; Device
Lead sponsor: Stryker Trauma and Extremities; Industry
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2036
U.S. locations: 4
States / cities: Denver, Colorado • Bradenton, Florida • Tampa, Florida + 1 more

Conditions: Infections, Gram-positive Bacterial
Interventions: Telavancin, vancomycin or antistaphylococcal penicillin; Drug
Lead sponsor: Cumberland Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 201 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004
U.S. locations: 1
States / cities: National City, California

Conditions: Diabetic Foot Ulcers
Interventions: Nexagon® Low Dose, Nexagon® Medium Dose, Nexagon® High Dose, Nexagon® vehicle; Drug
Lead sponsor: OcuNexus Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 168 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 9
States / cities: Phoenix, Arizona • Tucson, Arizona • Castro Valley, California + 6 more

Conditions: Lung Diseases, Obstructive, Sarcoidosis, Wegener's Granulomatosis, Rhinoscleroma, Recurrent Respiratory Papillomatosis
Interventions: CryoSpray Ablation; Device
Lead sponsor: CSA Medical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: HER2-positive Breast Cancer, HER2+ Breast Cancer
Interventions: Carvedilol, Empagliflozin; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Burns, Skin Graft Complications
Interventions: Tranexamic acid, Thrombin JMI, skin graft; Drug · Procedure
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Diabetic Foot Ulcer Outcome, Quality of Patient Care
Interventions: cellular and tissue based therapy, negative pressure wound therapy, debridement, advanced wound therapy, Nutritional screening, off-loading, Hyperbaric oxygen Therapy; Biological · Device · Procedure + 1 more
Lead sponsor: U.S. Wound Registry; Other
Eligibility: Not listed
Enrollment: 10,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2025
U.S. locations: 1
States / cities: The Woodlands, Texas

Conditions: Wounds, Wound of Skin, Wound Heal, Wounds and Injuries
Interventions: 4-Aminopyridine, Placebo; Drug · Other
Lead sponsor: John Elfar; Other
Eligibility: 18 Years to 70 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Wound Heal, Wound of Skin
Interventions: Factorial Assignment; Other
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Skin Carcinoma
Interventions: Best Practice, Educational Intervention, Electronic Health Record Review, Follow-Up Care, Medical Device Usage and Evaluation, Negative Pressure Wound Therapy, Photography, Questionnaire Administration; Other · Procedure
Lead sponsor: Jonsson Comprehensive Cancer Center; Other
Eligibility: 19 Years to 79 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Inflammatory Bowel Diseases
Interventions: Serial Biopsy; Procedure
Lead sponsor: Terrence A Barrett; Other
Eligibility: 18 Years to 90 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Chronic Lower Leg Ulcer, Diabetic Lower Extremity Ulcers, Pressure Injuries, Traumatic Wounds and Injuries, Surgical Wounds
Interventions: Motion NPWT; Device
Lead sponsor: West Boca Center for Wound Healing; Other
Eligibility: Not listed
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Coconut Creek, Florida

Conditions: Cardiac Toxicity, Malignant Neoplasm, Breast Cancer
Interventions: Magnetic resonance imaging, Physical Activity, Healthy Living, Cardiopulmonary Exercise Testing (CPET), Questionnaire Administration; Procedure · Other · Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 85 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2022
U.S. locations: 2
States / cities: Winston-Salem, North Carolina • Richmond, Virginia

Conditions: Malignant Melanoma, Merkel Cell Carcinoma, Basal Cell Carcinoma, Squamous Cell Carcinoma, Atypical Nevi, Congenital Nevi, Seborrheic Keratosis, Paget's Disease, Dermatofibroma, Kaposi's Sarcoma, Port Wine Stain, Hemangioma, Tattoos, Scleroderma, Burns
Interventions: Optical Biopsy imaging; Device
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years to 75 Years
Enrollment: 113 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1999 – 2008
U.S. locations: 1
States / cities: Irvine, California

Conditions: Non-healing Wound, Diabetic Foot Ulcer
Interventions: AC5® Advanced Wound System, Fibracol Plus Collagen Dressing; Device
Lead sponsor: Arch Therapeutics; Industry
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 2
States / cities: Greenville, North Carolina • Circleville, Ohio

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Effect of Orally Delivered Phytochemicals on Aging and Inflammation in the Skin

Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Matched Standard of Care Controls in the Management of Nonhealing Pressure Ulcers

Study of Oasis Ultra in Diabetic Foot Ulcers

Effects of Topical Vitamin K, Vitamin K and Retinol, and Arnica on Post-Laser Bruising

Matrion™ Decellularized Placental Membrane in Subjects With Diabetic Foot Ulcers

Evaluation of Wheelchair In-Seat Activity Tracker

A Clinical Study of the Safety and Efficacy of MEBO® Wound Ointment in Subjects With Diabetic Foot Ulcers (Pilot)

G7 Dual Mobility With Vivacit-E or Longevity PMCF

Efficacy of Topical TolaSure on Acute Induced Wounds in Healthy Participants

Tornier HRS (Humeral Reconstruction System) Study (REVIVE)

Phase 2 Trial of TD-6424 (Telavancin) Versus Standard Therapy for Complicated Gram Positive Skin and Skin Structure Infections (Gram Positive cSSSI)

A Study to Investigate the Safety and Clinical Effect of Nexagon® as a Topical Treatment for Subjects With a Diabetic Foot Ulcer (DUNE)

Interventional Cryotherapy for the Eradication of Benign Airway Disease ("ICE the BAD")

HER2HEART-US: Prevention of Cardiotoxicity in Breast Cancer Patients Receiving HER2-directed Therapy

Burn Study- Tranexamic Acid Versus Thrombin in Split Thickness Skin Graft

The Diabetic Foot Ulcer Registry

4-aminopyridine for Skin Wound Healing

Aesthetic Outcome of Complex Linear Closure vs Second Intention Healing: Below the Knee

A Disposable Negative Pressure Wound Therapy Device (SNaP) to Promote Wound Healing in the Lower Limbs Following Mohs Micrographic Surgery for Non-melanoma Skin Cancer

Regulation of Mucosal Healing in Inflammatory Bowel Disease

Use of Hydroprep Wound Therapy With Motion Negative Pressure Therapy for Treatment of Chronic Lower Extremity Wounds

MRI in Detecting Heart Damage in Patients With Cancer Receiving Chemotherapy With Exercise Capacity Addendum

Optical Biopsy of Human Skin in Conjunction With Laser Treatment

Use of AC5® Advanced Wound System in the Treatment of Diabetic Foot Ulcers