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ClinicalTrials.gov public records Last synced Oct 31, 2026, 2:10 AM EDT

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Showing 1–24 of 85 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Wounds, Closure Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Wound Closure Techniques

NCT00282633
View directory record Official record
Conditions
Wounds, Closure
Interventions
Dermabond
Device
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 31, 2007 · Synced Oct 31, 2026, 2:10 AM EDT
Completed Not applicable Interventional Results available

AMBULATE Continued Access Protocol to Evaluate the Cardiva Mid-Bore Venous Vascular Closure System (VVCS)

NCT03573206
View directory record Official record
Conditions
Surgical Wound
Interventions
Cardiva Mid-Bore Venous Vascular Closure Device (VVCS)
Device
Lead sponsor
Cardiva Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
3
States / cities
Atlanta, Georgia • Ridgewood, New Jersey • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 10, 2023 · Synced Oct 31, 2026, 2:10 AM EDT
Completed Not applicable Interventional

Post Operative Skin Approximation With Cyanoacrylate Based Wound Closure Adhesives

NCT07613892
View directory record Official record
Conditions
Wound Closure, Dehisced Surgical Wounds
Interventions
Evaluating wound closure products to close larger surgical site incisions, Evaluating wound closure products to close smaller surgical site incisions
Device
Lead sponsor
Medline Industries
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Johnstown, Colorado
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 31, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Skin Closure With Tissue Adhesives vs. Subcuticular Suture After Robotic Urogynecologic Procedures

NCT03891004
View directory record Official record
Conditions
Surgical Wound, Tissue Adhesion
Interventions
Subcuticular Skin Closure, Tissue Adhesives
Procedure · Device
Lead sponsor
St. John Hospital & Medical Center
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 4, 2019 · Synced Oct 31, 2026, 2:10 AM EDT
Completed Not applicable Interventional

Wound Eversion Versus Planar Closure for Face or Neck Wounds

NCT03302988
View directory record Official record
Conditions
Operative Wound
Interventions
Everted closure, Planar closure
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced Oct 31, 2026, 2:10 AM EDT
Completed Not applicable Interventional Results available

Comparison Between Wound Vacuum Dressing and Standard Closure to Reduce Rates of Surgical Site Infections

NCT03021668
View directory record Official record
Conditions
Surgical Site Infection, Pancreatic Neoplasms, Pancreatic Cancer, Chemotherapy Effects, Chemoradiation, Surgical Wound, Wound Complication
Interventions
Prevena Peel & Place Dressing, Standard Closure of the Surgical Incision
Device · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 31, 2026, 2:10 AM EDT
Completed Not applicable Interventional Results available

The Use of STRATAFIX Suture Device Compared to Standard-of-care for Deep Tissue Closure in Total Knee Arthroplasty

NCT03285529
View directory record Official record
Conditions
Wound; Knee
Interventions
STRATIFIX, VICRYL
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Oct 31, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Force Modulating Tissue Bridges for Closure of Vertical Scars in Breast Reduction

NCT05028816
View directory record Official record
Conditions
Surgical Incision
Interventions
Side 1: Final layer closure with force modulating tissue bridges (FMTB), Side 1: Final layer dermal closure with poliglecaprone 25 suture, Side 2: Final layer closure with force modulating tissue bridges (FMTB), Side 2: Final layer dermal closure with poliglecaprone 25 suture
Device · Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Oct 31, 2026, 2:10 AM EDT
Completed Not applicable Interventional Results available

ZIPS Study - Zip Incision aPproximation vs. Suture

NCT02213510
View directory record Official record
Conditions
Wound, Cardiac Arrhythmia
Interventions
Zip Surgical Skin Closure Device, Standard Suture Closure
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 30, 2016 · Synced Oct 31, 2026, 2:10 AM EDT
Completed Not applicable Interventional

Wound Closure Techniques in Primary Spine Surgery

NCT04396613
View directory record Official record
Conditions
Spinal Injuries
Interventions
Closure technique
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 31, 2026, 2:10 AM EDT
Completed Not applicable Interventional Results available

Vacuum Assisted Closure as a Treatment for Soft Tissue Injuries

NCT00582998
View directory record Official record
Conditions
Fracture of Calcaneus, Pilon or Tibial Plateau
Interventions
Standard Wound Dressing, Vacuum Assisted Closure Device
Procedure · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 25, 2019 · Synced Oct 31, 2026, 2:10 AM EDT
Completed Not applicable Interventional Results available

Suturing Distance From the Wound Edge, 2 mm vs 5 mm

NCT03330041
View directory record Official record
Conditions
Cutaneous Sutures and Scar Cosmesis
Interventions
Fast absorbing gut suture
Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 12, 2021 · Synced Oct 31, 2026, 2:10 AM EDT
Completed No phase listed Observational

Surgical Site Infection Rate After Intra-Abdominal Surgery Using Negative Pressure Wound Therapy at Initial Closure

NCT01924884
View directory record Official record
Conditions
Surgical Wound Infection, Wound; Abdomen, Abdominal Wall, Surgery
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 6, 2020 · Synced Oct 31, 2026, 2:10 AM EDT
Completed Not applicable Interventional Results available

Prospective Randomized Trial of Dermabond Prineo in Total Knee Arthroplasty

NCT03285542
View directory record Official record
Conditions
Wound Heal
Interventions
DERMABOND, Staples
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 13, 2021 · Synced Oct 31, 2026, 2:10 AM EDT
Terminated Not applicable Interventional Results available

Comparison Study of Wound Closure at Time of Cesarean Delivery: Dermabond Glue Versus Surgical Staples

NCT00524511
View directory record Official record
Conditions
Cesarean Section
Interventions
Surgical skin staples, Dermabond
Device
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
Female only
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 5, 2013 · Synced Oct 31, 2026, 2:10 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

NM-IL-12 (rHuIL-12) in Subjects With Open Surgical Wounds

NCT02544061
View directory record Official record
Conditions
Colostomy Stoma
Interventions
NM-IL-12, Placebo
Biological · Drug
Lead sponsor
Neumedicines Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
3
States / cities
Gainesville, Florida • Baltimore, Maryland • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 16, 2018 · Synced Oct 31, 2026, 2:10 AM EDT
Not yet recruiting Not applicable Interventional

Safety Study of Microlyte DualGuard

NCT07695688
View directory record Official record
Conditions
Wound Closure, Wound Care
Interventions
Microlyte DualGuard, Allevyn Foam (Standard of Care Control)
Device
Lead sponsor
Imbed Biosciences
Industry
Eligibility
22 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
3
States / cities
Phoenix, Arizona • Washington D.C., District of Columbia • New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 31, 2026, 2:10 AM EDT
Completed Phase 2 Interventional Results available

Study to Show Equivalence of DERMABOND PROTAPE to DERMABOND HVD for Wound Closure

NCT00547638
View directory record Official record
Conditions
Lacerations
Interventions
cyanoacrylate with pressure sensitive mesh, cyanoacrylate
Device
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
1 Year and older
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
9
States / cities
Phoenix, Arizona • Orlando, Florida • Indianapolis, Indiana + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2013 · Synced Oct 31, 2026, 2:10 AM EDT
Completed Not applicable Interventional

LiquiBand® Exceed™ and LiquiBand® Rapid™ for General Surgery Procedures

NCT04740775
View directory record Official record
Conditions
Surgical Wound
Interventions
LiquiBand Exceed, LiquiBand Rapid
Device
Lead sponsor
Advanced Medical Solutions Ltd.
Industry
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
4
States / cities
Columbus, Ohio • Greenville, South Carolina • Greer, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Oct 31, 2026, 2:10 AM EDT
Terminated Not applicable Interventional Results available

Closure of Fasciotomy Wounds: A Prospective, Observational Study of a Continuous External Tissue Expander

NCT01171534
View directory record Official record
Conditions
Wounds and Injuries, Compartment Syndrome
Interventions
DermaClose fasciotomy closure, Vessel loop
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 29, 2018 · Synced Oct 31, 2026, 2:10 AM EDT
Terminated Not applicable Interventional Results available

Secondary Versus Tertiary Wound Closure in High Risk Gynecologic Abdominal Surgical Incisions

NCT03861065
View directory record Official record
Conditions
Surgical Incision
Interventions
Tertiary Wound Closure, Historical Wound Closure
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 31, 2026, 2:10 AM EDT
Completed Not applicable Interventional

Aesthetic Outcome of Running Cuticular Suture Distance (2mm vs 5mm)

NCT04870008
View directory record Official record
Conditions
Suture, Dermatologic Surgery, Scar, Cosmetic Outcome
Interventions
Suture
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 3, 2021 · Synced Oct 31, 2026, 2:10 AM EDT
Recruiting Phase 3 Interventional

Safety and Efficacy of realSKIN® to Provide Complete Wound Closure of Burn Wounds as an Alternative to Autografting

NCT06223269
View directory record Official record
Conditions
Burns Degree Third, Burn (Disorder), Burn Degree Second, Thermal Burn, Wound Heal
Interventions
Skin Xenotransplant, Autograft(ing)
Drug · Procedure
Lead sponsor
XenoTherapeutics, Inc.
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
4
States / cities
Phoenix, Arizona • Augusta, Georgia • Portland, Maine + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Oct 31, 2026, 2:10 AM EDT
Terminated Phase 3 Interventional

Multi-Center, Prospective, Randomized Controlled Trial Evaluating SkinTE® in the Treatment of Wagner 2 DFUs

NCT05372809
View directory record Official record
Conditions
Diabetic Foot
Interventions
SkinTE, Control
Biological · Other
Lead sponsor
PolarityTE
Industry
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
13
States / cities
Fresno, California • Los Angeles, California • Hollywood, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2024 · Synced Oct 31, 2026, 2:10 AM EDT