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Showing 1–24 of 27 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Written Exposure Therapy Clear all
Completed Not applicable Interventional

Competitive Revision for CLARO: Collaboration Leading to Addiction Treatment and Recovery From Other Stresses

NCT04634279
View directory record Official record
Conditions
Opioid-use Disorder, Addiction, Depression, Post Traumatic Stress Disorder, Suicidal Ideation
Interventions
Collaborative care Plus
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
12
States / cities
Los Angeles, California • Santa Monica, California • Albuquerque, New Mexico + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 8, 2024 · Synced Jun 26, 2026, 9:46 AM EDT
Not yet recruiting Not applicable Interventional

Adaptation of Written Exposure Therapy in Substance Treatment

NCT07108608
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Substance Use Disorders
Interventions
Written Exposure Therapy, Treatment as Usual
Behavioral
Lead sponsor
Potomac Health Foundations
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Jun 26, 2026, 9:46 AM EDT
Completed Not applicable Interventional

Collaboration Leading to Addiction Treatment and Recovery From Other Stresses

NCT04559893
View directory record Official record
Conditions
Opioid-use Disorder, Addiction, Depression, Post-traumatic Stress Disorder
Interventions
Collaborative Care
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years and older
Enrollment
729 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
16
States / cities
Los Angeles, California • Santa Monica, California • Albuquerque, New Mexico + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Jun 26, 2026, 9:46 AM EDT
Recruiting Not applicable Interventional

Early Intervention for Postpartum PTSD: Comparing Written Exposure and Capnometry-Guided Breathing Therapy

NCT07342530
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Conditions
Written Exposure Therapy, Breathing Techniques, PTSD (Childbirth-Related), Postpartum Care
Interventions
Written Exposure Therapy (WET), Capnometry-Guided Breathing Intervention (CGRI)
Behavioral · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Little Rock, Arkansas • Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Jun 26, 2026, 9:46 AM EDT
Enrolling by invitation Not applicable Interventional

Developing and Testing Innovative Care Pathways for Screening and Treatment of OUD/PTSD in Jails

NCT07490717
View directory record Official record
Conditions
Post-traumatic Stress Disorder (PTSD), Post-traumatic Stress Symptoms, Opioid Use Disorder (OUD), Stimulant Use Disorder, Stimulant Use & Co-occuring Opioid Use Disorders, Co-occurring Mental and Substance Use Disorders, Medications for Opioid Use Disorder
Interventions
Cognitive Processing Therapy (CPT), Written Exposure Therapy (WET)
Other
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
338 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Jun 26, 2026, 9:46 AM EDT
Completed Not applicable Interventional

Evaluating Supplementing Residential Substance Use Treatment With Written Exposure Therapy for Veterans With Post Traumatic Stress Disorder (PTSD) and Substance Use Disorders (SUD)

NCT05536908
View directory record Official record
Conditions
PTSD, Substance Use Disorders
Interventions
Residential Written Exposure Therapy, Treatment as Usual
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Salem, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Jun 26, 2026, 9:46 AM EDT
Completed Not applicable Interventional

Written Versus Verbal Brief Cognitive Behavioral Exposure Therapy

NCT04000217
View directory record Official record
Conditions
Written Exposure Therapy, Imaginal Exposure Therapy
Interventions
Written Exposure Therapy, Imaginal Exposure Therapy
Behavioral
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
18 Years to 99 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Jun 26, 2026, 9:46 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Building Experience for Treating Trauma and Enhancing Resilience (BETTER)

NCT05330442
View directory record Official record
Conditions
PTSD
Interventions
Written Exposure Therapy (WET)
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years and older
Enrollment
720 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
10
States / cities
Albion, New York • Brooklyn, New York • Corfu, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Jun 26, 2026, 9:46 AM EDT
Completed Early Phase 1 Interventional

Written Exposure Therapy for Nurses

NCT06432374
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Depressive Symptoms, Burn Out, Anxiety, Work Related Stress
Interventions
WET
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 28, 2024 · Synced Jun 26, 2026, 9:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Written Exposure Therapy to Improve Recovery Among Sexual Assault Survivors

NCT06571513
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Written Exposure Therapy, Unemotional Writing
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Jun 26, 2026, 9:46 AM EDT
Recruiting Not applicable Interventional

Written Exposure Therapy for Suicide Prevention

NCT05878795
View directory record Official record
Conditions
Suicide, Attempted, Suicide Threat
Interventions
WET-SP, TAU
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Jun 26, 2026, 9:46 AM EDT
Completed Not applicable Interventional

Examining Written Disclosure as a Treatment for Post-Traumatic Stress Disorder

NCT00862498
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Conditions
Post-Traumatic Stress Disorder
Interventions
Written Disclosure
Other
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 27, 2018 · Synced Jun 26, 2026, 9:46 AM EDT
Completed Not applicable Interventional

Written Exposure in Substance Treatment

NCT06296940
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Substance Use Disorders
Interventions
Written Exposure Therapy, Treatment as Usual
Behavioral
Lead sponsor
Potomac Health Foundations
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 9, 2025 · Synced Jun 26, 2026, 9:46 AM EDT
Recruiting Not applicable Interventional

rTMS-augmented Written Exposure Therapy for PTSD

NCT05149534
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Written Exposure Therapy, repetitive transcranial magnetic stimulation
Behavioral · Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Temple, Texas
Source: ClinicalTrials.gov public record
Updated Jan 11, 2026 · Synced Jun 26, 2026, 9:46 AM EDT
Terminated Not applicable Interventional

New Beginnings Following Trauma

NCT05817344
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Opioid Use Disorder
Interventions
Written Exposure Therapy - Integrated
Behavioral
Lead sponsor
Jesse McCann
Other
Eligibility
18 Years to 100 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 9, 2025 · Synced Jun 26, 2026, 9:46 AM EDT
Recruiting Not applicable Interventional

Written Exposure Therapy for Veterans With SUD and PTSD

NCT05327504
View directory record Official record
Conditions
Substance Use Disorders, Posttraumatic Stress Disorder
Interventions
Written Exposure Therapy, Neutral Topic Writing
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Jun 26, 2026, 9:46 AM EDT
Active, not recruiting Not applicable Interventional

Empowering Perinatal Adolescents Through Writing

NCT06771817
View directory record Official record
Conditions
Post-Traumatic Stress Disorder in Adolescence, PTSD - Post Traumatic Stress Disorder, PTSD and Trauma-related Symptoms, Pregnancy and PTSD
Interventions
Written Exposure Therapy
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
15 Years to 24 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Jun 26, 2026, 9:46 AM EDT
Completed Not applicable Interventional Results available

Written Exposure Therapy Versus Prolonged Exposure: a Non-inferiority Trial

NCT03962504
View directory record Official record
Conditions
PTSD
Interventions
trauma-focused treatment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
3
States / cities
Boston, Massachusetts • Charleston, South Carolina • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 17, 2024 · Synced Jun 26, 2026, 9:46 AM EDT
Completed Phase 2 Interventional Results available

Adding Trauma-focused Psychotherapy to Ketamine Treatment for Chronic PTSD

NCT04889664
View directory record Official record
Conditions
PTSD
Interventions
Ketamine, Written Exposure Therapy
Drug · Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 70 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Manhattan, New York
Source: ClinicalTrials.gov public record
Updated Oct 7, 2024 · Synced Jun 26, 2026, 9:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Written Exposure Therapy for Posttraumatic Stress Disorder

NCT01800773
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Written Exposure Therapy, Cognitive Processing Therapy
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Jun 26, 2026, 9:46 AM EDT
Completed Not applicable Interventional

Decreasing Suicide Risk Among Service Members With Posttraumatic Stress

NCT04225130
View directory record Official record
Conditions
Suicide, Posttraumatic Stress Disorder
Interventions
Written Exposure Therapy -for Suicide, Treatment as Usual
Behavioral
Lead sponsor
Boston VA Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated Oct 30, 2023 · Synced Jun 26, 2026, 9:46 AM EDT
Terminated Not applicable Interventional Results available

Early Psychological Intervention to Prevent Cardiovascular Event-Induced PTSD (REACH Sub-study)

NCT03605693
View directory record Official record
Conditions
Acute Coronary Syndrome, TIA, Stroke, Cardiac Arrest, PTSD
Interventions
Written Exposure Therapy
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 15, 2020 · Synced Jun 26, 2026, 9:46 AM EDT
Active, not recruiting Not applicable Interventional

Adaptation and Randomized Controlled Trial of Written Exposure Therapy for Adolescents

NCT07498257
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Written Exposure Therapy, Trauma-focused Cognitive Behavior Therapy
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years to 18 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Jun 26, 2026, 9:46 AM EDT
Terminated Not applicable Interventional

Reclaiming Your Life After Sexual Trauma

NCT05268367
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Sexual Assault and Rape
Interventions
Written Exposure Therapy
Behavioral
Lead sponsor
Jesse McCann
Other
Eligibility
18 Years to 100 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Jun 26, 2026, 9:46 AM EDT