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Showing 1–24 of 92 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Youth Drinking Clear all
Recruiting Not applicable Interventional

Evaluating Caregiver Involvement in Primary Care-Based Brief Interventions for Adolescent Alcohol Use Problems

NCT06593652
View directory record Official record
Conditions
Alcohol Use, Adolescent, Mild Alcohol Use Disorder, Mild Substance Use Disorder
Interventions
Teen Intervene - Adolescent Only, Teen Intervene with Caregiver Session, Family Check Up
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
12 Years to 17 Years
Enrollment
615 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 1, 2026 · Synced Sep 11, 2026, 7:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brief Youth Substance Use Intervention for Primary Care

NCT00292240
View directory record Official record
Conditions
Alcohol Consumption, Drug Abuse
Interventions
Brief motivational substance use intervention
Behavioral
Lead sponsor
RAND
Other
Eligibility
12 Years to 18 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2024 · Synced Sep 11, 2026, 7:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Testing a Brief Substance Misuse Preventative Intervention for Parents/Guardians of 5th-7th Grade Students

NCT03925220
View directory record Official record
Conditions
Substance-Related Disorders, Underage Drinking, Drug Use
Interventions
The SUPPER Project, Improving nutrition and physical activity among youth
Behavioral
Lead sponsor
Tufts University
Other
Eligibility
9 Years to 14 Years
Enrollment
402 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Sep 11, 2026, 7:14 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Computerized Screening and Brief Physician Advice to Reduce Teen Drinking

NCT00849589
View directory record Official record
Conditions
Alcohol Abuse, Risk Behavior
Interventions
Computerized screening and brief physician advice, Computerized SBA with technological extenders
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 6, 2016 · Synced Sep 11, 2026, 7:14 AM EDT
Completed Not applicable Interventional

SafERteens M-Coach

NCT03344666
View directory record Official record
Conditions
Alcohol Drinking, Violence
Interventions
Step 1 Treatment BI+HC, Step 1 Treatment BI+TM, Step 2 Treatment Responders, Step 2 Treatment Non-Responders
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 20 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
4
States / cities
Ann Arbor, Michigan • Detroit, Michigan • Flint, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 4, 2024 · Synced Sep 11, 2026, 7:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A High School Program for Preventing Prescription Drug Misuse

NCT03219190
View directory record Official record
Conditions
Prescription Drug Abuse, Substance Abuse, Substance Use (Drugs, Alcohol)
Interventions
LST High School Hybrid
Behavioral
Lead sponsor
National Health Promotion Associates, Inc.
Industry
Eligibility
14 Years to 18 Years
Enrollment
1,804 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 11, 2026, 7:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An e-Parenting Skills Intervention to Decrease Injured Adolescents' Alcohol Use

NCT02718508
View directory record Official record
Conditions
Parenting, Alcohol Drinking
Interventions
eParenting
Behavioral
Lead sponsor
Michael J. Mello, MD, MPH
Other
Eligibility
12 Years to 17 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 10, 2018 · Synced Sep 11, 2026, 7:14 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Journey of Transformation Curriculum for Native American Adolescents

NCT05274217
View directory record Official record
Conditions
Alcohol Use, Tobacco Use, Substance Use, Sexual Health
Interventions
Journey of Transformation-Native Youth Health Leadership Program curriculum
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
13 Years to 16 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 3, 2023 · Synced Sep 11, 2026, 7:14 AM EDT
Completed Phase 2 Interventional Results available

Enhancing the Effects of Alcohol Treatment With Lamotrigine

NCT04770493
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Lamotrigine, Placebo
Drug
Lead sponsor
Brown University
Other
Eligibility
16 Years to 24 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Sep 11, 2026, 7:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Community-Based Strategy for Preventing Underage Drinking

NCT02448134
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Youth Access
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
13 Years to 19 Years
Enrollment
7,379 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 15, 2020 · Synced Sep 11, 2026, 7:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindfulness for at Risk Youth: Understanding Substance Use and Important Mechanisms of Change

NCT04160754
View directory record Official record
Conditions
Alcohol Use, Underage, Alcohol Problem Drinking, Substance Use
Interventions
Mindfulness Based Relapse Prevention, Control (CTL)
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 26 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Sep 11, 2026, 7:14 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Parent Intervention to Reduce College Student Drinking and Consequences

NCT04247191
View directory record Official record
Conditions
Underage Drinking, Driving Under the Influence, Drinking, Teen, Drinking, College
Interventions
P-Chat+, PBI
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 19 Years
Enrollment
2,061 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 11, 2026, 7:14 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Collaborative Care PrTNER Study

NCT06585631
View directory record Official record
Conditions
HIV, Substance Use Disorders, Substance Use, AIDS
Interventions
CC PrTNER
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
15 Years to 29 Years · Male only
Enrollment
275 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
2
States / cities
Baltimore, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 11, 2026, 7:14 AM EDT
Completed Phase 1 Interventional

Community-Based Integrated Treatment for Adolescents

NCT01667159
View directory record Official record
Conditions
Depression, Alcohol Use
Interventions
Integrated Cognitive Behavioral Therapy, Standard Care
Behavioral
Lead sponsor
Brown University
Other
Eligibility
12 Years to 18 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced Sep 11, 2026, 7:14 AM EDT
Completed Phase 2 Interventional

Home Based Treatment for Drug Use in Early Adolescents

NCT00280228
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder, Oppositional Defiant Disorder, Conduct Disorder, Substance Abuse
Interventions
Adolescent Skills Parent Management Parent-Adol Negotiation, Treatment as Usual
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
11 Years to 14 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 25, 2011 · Synced Sep 11, 2026, 7:14 AM EDT
Terminated Not applicable Interventional

Assessing the Fit of Motivational Interviewing by Cultures With Adolescents

NCT01948700
View directory record Official record
Conditions
Alcoholism
Interventions
Motivational Interviewing, Education
Behavioral · Other
Lead sponsor
University of New Mexico
Other
Eligibility
13 Years to 18 Years
Enrollment
506 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Mar 11, 2024 · Synced Sep 11, 2026, 7:14 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Native Spirit: Significant Aim 3: Intervention

NCT06785311
View directory record Official record
Conditions
Substance Use, Self Esteem, Youth Drinking, Prevention, Suicide
Interventions
Native Spirit After-School Program
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
12 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Scottsdale, Arizona • Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 11, 2026, 7:14 AM EDT
Completed Phase 2 Interventional

Brief Voluntary Alcohol and Drug Intervention for Middle School Youth

NCT01081119
View directory record Official record
Conditions
Alcohol Drinking, Cigarette Smoking, Marijuana Smoking
Interventions
Project CHOICE
Behavioral
Lead sponsor
RAND
Other
Eligibility
11 Years to 15 Years
Enrollment
6,455 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2014 · Synced Sep 11, 2026, 7:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intergenerational Strengths-Based Program for American Indian Girls as They Transition to Adulthood

NCT03900312
View directory record Official record
Conditions
Sexual Activity, Sex, Alcohol Use, Pregnancy, Drug Use
Interventions
Asdzaan Be'eena' Program
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
8 Years and older · Female only
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chinle, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 3, 2020 · Synced Sep 11, 2026, 7:14 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Think AHEAD (A Healthy Eating And Drinking) Study

NCT01044134
View directory record Official record
Conditions
Obesity
Interventions
Dietary counseling
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 17 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 28, 2015 · Synced Sep 11, 2026, 7:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Family Based Prevention of Alcohol and Risky Sex for Older Teens

NCT03521115
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Intoxication, Alcohol Poison, Alcohol-Related Disorders, Alcohol Impairment, Alcohol Withdrawal, Alcohol Abstinence, Alcohol; Harmful Use, Sex Behavior, Sexual Aggression, Sexual Harassment, Relation, Interpersonal
Interventions
Smart Choices 4 Teens
Behavioral
Lead sponsor
Pacific Institute for Research and Evaluation
Other
Eligibility
16 Years to 17 Years
Enrollment
411 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced Sep 11, 2026, 7:14 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Effects of Topiramate on Adolescent Alcohol Use: Efficacy and Mechanisms

NCT01641445
View directory record Official record
Conditions
Alcohol Drinking
Interventions
Topiramate, Placebo
Drug
Lead sponsor
Brown University
Other
Eligibility
14 Years to 24 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Sep 11, 2026, 7:14 AM EDT
Not listed Not applicable Interventional

Computer Adaptation of Screening, Brief MET Intervention to Reduce Teen Drinking

NCT01881841
View directory record Official record
Conditions
Alcohol Abuse, Tobacco Use Disorder, Substance Use
Interventions
cMET
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
14 Years to 20 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 19, 2017 · Synced Sep 11, 2026, 7:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Healthy Families Bright Futures Program

NCT06309134
View directory record Official record
Conditions
Alcohol Drinking, Violence in Adolescence
Interventions
Healthy Families Bright Futures Program
Behavioral
Lead sponsor
University of Colorado, Colorado Springs
Other
Eligibility
15 Years to 18 Years
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 11, 2026, 7:14 AM EDT