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Showing 1–24 of 58 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: at Risk for HIV Clear all
Terminated Not applicable Interventional Accepts healthy volunteers

Scalable Interventions to Increase PrEP Adherence: Value Affirmation and Future Selves

NCT03278990
View directory record Official record
Conditions
HIV Prevention
Interventions
Value Affirmation and Future Selves Combination, Control writing exercise
Behavioral
Lead sponsor
Stuart Fisk
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 10, 2021 · Synced Jun 26, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Young Women's Health CoOp (Cooperative) in Cape Town

NCT02677025
View directory record Official record
Conditions
HIV, Substance Abuse
Interventions
Young Women's Health CoOp (YWHC), HIV Counseling/Testing
Behavioral
Lead sponsor
RTI International
Other
Eligibility
16 Years to 21 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Jun 26, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The LEARN Study for CVD Prevention

NCT05242952
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Gaming in a virtual environment
Behavioral
Lead sponsor
Yale University
Other
Eligibility
30 Years to 65 Years · Male only
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Orange, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 27, 2025 · Synced Jun 26, 2026, 9:24 AM EDT
Completed Phase 1 Interventional

A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 (rCD4) in Infants and Children Infected With or at Risk for HIV Infection

NCT00000984
View directory record Official record
Conditions
HIV Infections
Interventions
CD4 Antigens
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
1 Day to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
6
States / cities
San Francisco, California • Stanford, California • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Jun 26, 2026, 9:24 AM EDT
Completed No phase listed Observational

Vascular Subphenotypes of Lung Disease in HIV & COPD

NCT01581086
View directory record Official record
Conditions
Pulmonary Artery Hypertension
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Jun 26, 2026, 9:24 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Evaluation of a New HIV Prevention Intervention for Black Bisexually-active Men

NCT01347164
View directory record Official record
Conditions
Bisexually-active Men, at Risk for HIV
Interventions
RISE life coaching intervention, HIV Counseling
Behavioral
Lead sponsor
Public Health Management Corporation
Other
Eligibility
18 Years and older · Male only
Enrollment
169 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 16, 2018 · Synced Jun 26, 2026, 9:24 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Reducing Sexual Risk Behaviors and Improving Health for People at a Sexually Transmitted Infection Clinic

NCT00947271
View directory record Official record
Conditions
HIV, Sexually Transmitted Diseases, HIV Infections
Interventions
DVD 1, DVD 2
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
16 Years and older
Enrollment
1,010 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 16, 2014 · Synced Jun 26, 2026, 9:24 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

This Study Evaluates the ALPCO Syphilis-T and Syphilis-NT CLIA Kits for Detecting Syphilis Antibodies in Serum and Plasma. Samples From At-risk, HIV-positive, Pregnant, and Healthy Individuals Will Assess Assay Performance Versus Established Comparator Tests.

NCT07089836
View directory record Official record
Conditions
Treponema Pallidum, Treponema Pallidum Infection, Syphilis Infection, Serum, Plasma, Blooddraw, Sexually Transmitted Infection (STI)
Interventions
ALPCO Syphilis-T, ALPCO Syphilis-NT CLIA Kits
Device
Lead sponsor
American Laboratory Products Company
Industry
Eligibility
13 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
6
States / cities
Lancaster, California • Los Angeles, California • North Miami, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Jun 26, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acceptability, Feasibility and Preliminary Impact of OurPlan, an mHealth HIV Prevention Intervention for Male Couples

NCT04836091
View directory record Official record
Conditions
HIV/AIDS
Interventions
Waitlist, Intervention
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 15, 2021 · Synced Jun 26, 2026, 9:24 AM EDT
Completed Not applicable Interventional

A Self-Assessment Intervention for Young Adult Polydrug Users at Risk for HIV

NCT01362634
View directory record Official record
Conditions
HIV Infection, Substance Abuse
Interventions
Trans-theoretical Process of Change Model-self, Trans-theoretical Process of Change Model - interviewer
Behavioral
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 39 Years
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 6, 2017 · Synced Jun 26, 2026, 9:24 AM EDT
Completed Phase 3 Interventional

Case Management Alternatives for African American Women at High Risk for HIV

NCT00780260
View directory record Official record
Conditions
HIV
Interventions
strengths-based case management
Behavioral
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
562 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 10, 2013 · Synced Jun 26, 2026, 9:24 AM EDT
Withdrawn Phase 2 Interventional

A Study to Learn About the Medicine Called Nirmatrelvir Used in Combination With Ritonavir in People With Weakened Immune Systems or at Increased Risk for Poor Outcomes Who Are Hospitalized Due to Severe COVID-19

NCT05545319
View directory record Official record
Conditions
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Coronavirus Disease 2019 (COVID-19), Immunocompromised, Hospitalization, Child, Hospitalized
Interventions
Nirmatrelvir, Ritonavir, Placebo for nirmatrelvir
Drug
Lead sponsor
Pfizer
Industry
Eligibility
12 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Cooperstown, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 28, 2023 · Synced Jun 26, 2026, 9:24 AM EDT
Completed No phase listed Observational

Eliminating Hepatitis C Virus

NCT03401697
View directory record Official record
Conditions
Hepatitis C, HIV, Type2 Diabetes
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
52 participants
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 23, 2021 · Synced Jun 26, 2026, 9:24 AM EDT
Completed Phase 2Phase 3 Interventional

Peer-driven Intervention to Seek, Test & Treat Heterosexuals at High Risk for HIV

NCT01607541
View directory record Official record
Conditions
HIV/AIDS
Interventions
BCAP peer-driven intervention (PDI), Control intervention
Behavioral
Lead sponsor
New York University
Other
Eligibility
18 Years to 60 Years
Enrollment
3,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 2, 2022 · Synced Jun 26, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Peer Outreach and Navigation Intervention to Increase PrEP Uptake Among Women at High Risk for HIV

NCT03226873
View directory record Official record
Conditions
Pre-exposure Prophylaxis, HIV-1-infection
Interventions
Peer Navigation
Behavioral
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2018 · Synced Jun 26, 2026, 9:24 AM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Oral Islatravir (MK-8591) Once-Monthly as Preexposure Prophylaxis (PrEP) in Men and Transgender Women Who Are at High Risk for HIV-1 Infection (MK-8591-024)

NCT04652700
View directory record Official record
Conditions
HIV Preexposure Prophylaxis
Interventions
ISL, FTC/TDF, FTC/TAF, Placebo to ISL, Placebo to FTC/TDF, Placebo to FTC/TAF
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
16 Years and older · Male only
Enrollment
494 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
15
States / cities
Birmingham, Alabama • Los Angeles, California • San Francisco, California + 11 more
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Jun 26, 2026, 9:24 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

TelePrEP for At-risk Youth in Colorado

NCT05520905
View directory record Official record
Conditions
Hiv
Interventions
TelePrEP
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
14 Years to 24 Years · Male only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Jun 26, 2026, 9:24 AM EDT
Completed No phase listed Observational

Prevention and Treatment Continuum for Youth at HIV Risk, Acutely Infected and With Established HIV Infection

NCT03205696
View directory record Official record
Conditions
Human Immunodeficiency Virus
Interventions
Antiretrovirals
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
12 Years to 24 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
3
States / cities
Los Angeles, California • New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 24, 2025 · Synced Jun 26, 2026, 9:24 AM EDT
Completed Phase 2 Interventional Results available

A Clinical Trial for People HIV+ Age > 50 at Risk for Heart Disease

NCT01578772
View directory record Official record
Conditions
Endothelial Dysfunction
Interventions
Telmisartan
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
50 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 7, 2014 · Synced Jun 26, 2026, 9:24 AM EDT
Completed Phase 3 Interventional Results available

Buprenorphine Group Medical Visits in Primary Care

NCT02526212
View directory record Official record
Conditions
Opioid-Related Disorders
Interventions
G-BMT, Treatment as usual, Buprenorphine
Behavioral · Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Jun 26, 2026, 9:24 AM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Oral ISL QM as PrEP in Cisgender Women at High Risk for HIV-1 Infection (MK-8591-022)

NCT04644029
View directory record Official record
Conditions
HIV-I, Human Immunodeficiency Virus Type 1, Prophylaxis
Interventions
Islatravir, Placebo to FTC/TDF, FTC/TDF, Placebo to ISL
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
16 Years to 45 Years · Female only
Enrollment
730 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
13
States / cities
Birmingham, Alabama • Washington D.C., District of Columbia • Miami, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Jun 26, 2026, 9:24 AM EDT
Completed Not applicable Interventional

Targeting PM to Improve HIV Adherence in Adolescents at Risk for Substance Abuse

NCT01959217
View directory record Official record
Conditions
Adherence, Substance Abuse
Interventions
PM Component Text Reminders
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
16 Years to 29 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
La Jolla, California • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 9, 2018 · Synced Jun 26, 2026, 9:24 AM EDT
Completed Not applicable Interventional

Youth Services Navigation Intervention for HIV+ Youth Being Released From or At-risk for Incarceration

NCT03584932
View directory record Official record
Conditions
HIV/AIDS
Interventions
LINK2 Youth Services Navigation Intervention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
16 Years to 25 Years · Male only
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Jun 26, 2026, 9:24 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Safety and Pharmacokinetics of Oral Islatravir (MK-8591) Once Monthly in Participants at Low Risk of Human Immunodeficiency Virus 1 (HIV-1) Infection (MK-8591-016)

NCT04003103
View directory record Official record
Conditions
HIV-1 Infection
Interventions
Islatravir, Placebo
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
242 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
4
States / cities
Hollywood, Florida • Baltimore, Maryland • Lincoln, Nebraska + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2025 · Synced Jun 26, 2026, 9:24 AM EDT