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ClinicalTrials.gov public records Last synced Oct 18, 2026, 2:39 PM EDT

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Showing 1–24 of 58 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: fNIRS Clear all
Recruiting Not applicable Interventional

Testing Personalized High-Definition Transcranial Direct Current Stimulation (HD-tDCS) as a Treatment of Posterior Cortical Atrophy

NCT07191327
View directory record Official record
Conditions
Posterior Cortical Atrophy
Interventions
HD-tDCS sessions, Sham HD-tDCS sessions, HD-tDCS sessions - Open-label (after randomized treatment)
Device
Lead sponsor
University of Michigan
Other
Eligibility
50 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 18, 2026, 2:39 PM EDT
Completed Not applicable Interventional

Pilot Trial for Adults With Acquired Brain Injury

NCT05793827
View directory record Official record
Conditions
Acquired Brain Injury, Traumatic Brain Injury, Stroke
Interventions
Adapted Hatha Yoga, Low-Impact Exercise
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 26, 2024 · Synced Oct 18, 2026, 2:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Visual and Auditory Neuromodulation of Pain Perception

NCT04281836
View directory record Official record
Conditions
Pain, Acute
Interventions
Interoceptive breathing awareness through use of audio and visual virtual technology aid, Interoceptive breathing awareness without use of audio or visual virtual reality
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 24, 2020 · Synced Oct 18, 2026, 2:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Short-Term Creatine Supplementation on Cognitive Function in Healthy Young Adults

NCT07867041
View directory record Official record
Conditions
Cognitive Function Assessment, Mental Fatigue
Interventions
Creatine Monohydrate, Maltodextrin Placebo
Dietary Supplement
Lead sponsor
University of Northern Iowa
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Cedar Falls, Iowa
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 18, 2026, 2:39 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Sport-Related Concussion Recovery in Athletes

NCT06852300
View directory record Official record
Conditions
Concussion Mild, Concussion, Brain
Interventions
Concussion Assessment Battery
Device
Lead sponsor
University of Central Arkansas
Other
Eligibility
18 Years to 26 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2030
U.S. locations
1
States / cities
Conway, Arkansas
Source: ClinicalTrials.gov public record
Updated Mar 6, 2025 · Synced Oct 18, 2026, 2:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Neural Mechanisms of Split-belt Treadmill Adaptation in People With Multiple Sclerosis

NCT05878873
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Split-belt Treadmill, Transcutaneous Electrical Nerve Stimulation (TENS)
Behavioral · Device
Lead sponsor
Colorado State University
Other
Eligibility
18 Years to 86 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Oct 18, 2026, 2:39 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Rural Autistic Individuals - Supporting Expression

NCT07054866
View directory record Official record
Conditions
Autism Disorder, Language Development Disorders, ADHD, Typical Development, Rural Health, Children, Neuroimaging, Eye Tracking, EEG, fNIRS
Interventions
Speech-Gesture combinations
Behavioral
Lead sponsor
Montana State University
Other
Eligibility
2 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 18, 2026, 2:39 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Near-InfraRed Spectroscopy of Auricular Stimulation

NCT06825364
View directory record Official record
Conditions
Healthy Male and Female Subjects, Healthy Volunteer Study
Interventions
auricular stimulation
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 18, 2026, 2:39 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Spatial Cues, Task Demands, and Auditory Selective Attention

NCT07765186
View directory record Official record
Conditions
Bilateral Cochlear Implants, Hearing Loss, Bilateral, Healthy
Interventions
Existing bilateral cochlear implants, Normal Hearing Control
Device · Other
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 18, 2026, 2:39 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Functional Evaluation in Patients With Urea Cycle Disorders (UCD) During a Driving Task

NCT07701694
View directory record Official record
Conditions
Urea Cycle Disorder
Interventions
Not listed
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
16 Years to 40 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2032
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 18, 2026, 2:39 PM EDT
Completed Not applicable Interventional

Functional Near-Infrared Spectroscopy (fNIRS) Assessing Neural Activity During Virtual Reality Walking Intervention

NCT06276894
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Motek C-Mill™ treadmill, training session with and without VR wearing the fNIRS cap
Device · Other
Lead sponsor
Craig Hospital
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 18, 2026, 2:39 PM EDT
Completed Early Phase 1 Interventional

Feasibility of Near-infrared Spectroscopy to Measure Cortical Pain Pathway (Brain) Activation During Dry Needling

NCT04170803
View directory record Official record
Conditions
Shoulder Pain, Chronic Pain, Musculoskeletal Injury
Interventions
Dry Needling, Sham Dry Needling
Device · Other
Lead sponsor
Army-Baylor University Doctoral Program in Physical Therapy
Other
Eligibility
18 Years to 50 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Oct 18, 2026, 2:39 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Detection of Hemodynamic Changes in TBI Population With Functional Near Infrared Spectroscopy

NCT01797549
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 17, 2019 · Synced Oct 18, 2026, 2:39 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Neural Mechanisms of the Contextual Interference Effect: A fNIRs and EEG Study

NCT01134978
View directory record Official record
Conditions
Healthy Individuals, Learning
Interventions
Practice Order
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 7, 2011 · Synced Oct 18, 2026, 2:39 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

fNIRS for Disorders of Consciousness

NCT07485361
View directory record Official record
Conditions
Disorders of Consciousness Due to Severe Brain Injury, Disorders of Consciousness, Coma, Minimally Conscious State, Unresponsive Wakefulness Syndrome, Brain Injury, TBI Traumatic Brain Injury
Interventions
Functional Near-Infrared Spectroscopy Monitoring
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 18, 2026, 2:39 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Postural Control During Concurrent Cognitive Tasks During Optic Flow Stimulation

NCT05117463
View directory record Official record
Conditions
Aging, Postural Balance
Interventions
Optic Flow Stimulation, Auditory Reaction Time
Other
Lead sponsor
Chia-Cheng Lin, PhD, PT, MSPT
Other
Eligibility
25 Years to 85 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Oct 18, 2026, 2:39 PM EDT
Completed Not applicable Interventional Results available

Child Characteristics, Neuromarkers, and Intervention Components Impacting Treatment Outcome: CCT, TF-CBT, TAU

NCT02926677
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Cue-Centered Treatment (CCT), Trauma-Focused CBT (TF-CBT), Treatment as Usual, NIRScout
Behavioral · Device
Lead sponsor
Stanford University
Other
Eligibility
7 Years to 18 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Sacramento, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2021 · Synced Oct 18, 2026, 2:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Testing and Calibration of Non-Invasive Optical Imaging Technology for Functional Brain Imaging

NCT01212029
View directory record Official record
Conditions
Cognition
Interventions
Behavioral measures, fNIRS Devices & Application, Physiological measures
Behavioral · Device · Other
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years to 99 Years
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2024
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 17, 2025 · Synced Oct 18, 2026, 2:39 PM EDT
Completed No phase listed Observational

Functional Near Infrared Spectroscopy to Detect Pain in Young Children Under General Anesthesia

NCT04362423
View directory record Official record
Conditions
Pain
Interventions
fNIRS
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Month to 16 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced Oct 18, 2026, 2:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving Locomotor Learning With Brain Stimulation

NCT06414213
View directory record Official record
Conditions
Motor Learning
Interventions
Motor Imagery (MI), Active tDCS, Sham tDCS
Behavioral · Device
Lead sponsor
Appalachian State University
Other
Eligibility
18 Years to 99 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Boone, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Oct 18, 2026, 2:39 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Investigating Mild Cognitive Impairment in Patients And Controls With TD-fNIRS

NCT05996575
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
fNIRS measurement
Other
Lead sponsor
Kernel
Industry
Eligibility
55 Years to 85 Years
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
6
States / cities
Carlsbad, California • Costa Mesa, California • Escondido, California + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 18, 2026, 2:39 PM EDT
Not yet recruiting Not applicable Interventional

VR-PAT and fNIRS to Identify CNS Biomarkers of Pain

NCT06303687
View directory record Official record
Conditions
Acute Pain, Pediatric ALL, Procedural Pain, Burns
Interventions
VR-PAT
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
6 Years to 17 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 18, 2026, 2:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of the Q-Collar During High-Intensity Cycling Exercise

NCT07808710
View directory record Official record
Conditions
Physiological Responses to High-Intensity Exercise
Interventions
Q-Collar™
Device
Lead sponsor
University of Northern Iowa
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Cedar Falls, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 18, 2026, 2:39 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Functional Near-Infrared Spectroscopy and Virtual Reality Relaxation Programs for Pain Management in Patients With Cancer

NCT06456411
View directory record Official record
Conditions
Breast Carcinoma, Kidney Carcinoma, Carcinoma
Interventions
Functional Near-Infrared Spectroscopy, Questionnaire Administration, Virtual Technology Intervention, Cold Stimulation
Procedure · Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 18, 2026, 2:39 PM EDT