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ClinicalTrials.gov public records Last synced Sep 29, 2026, 2:11 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Conditions
Posttraumatic Stress Disorder, Substance Abuse
Interventions
Cognitive behavioral treatment enhanced by virtual reality
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
New York, New York
Conditions
Alcohol Abuse, Posttraumatic Stress Disorder
Interventions
Prazosin, Placebo medication
Drug
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Depression, Substance Abuse, Substance Use, Neuroimaging, Dual Diagnosis
Interventions
Creatine monohydrate
Drug
Lead sponsor
Perry Renshaw
Other
Eligibility
13 Years to 64 Years · Female only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Withdrawn Phase 2 Interventional

Zonisamide Outpatient Study

NCT03376139
Conditions
Post Traumatic Stress Disorder, Alcohol Use Disorder
Interventions
Zonisamide, Placebo Comparator
Drug
Lead sponsor
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
Other
Eligibility
18 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Houston, Texas
Conditions
Substance Misuse, Violence, Domestic, Child Abuse
Interventions
Fathers for Change (F4C), Individual Drug Counseling (IDC)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Male only
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
2
States / cities
New Haven, Connecticut • West Haven, Connecticut
Recruiting Not applicable Interventional

tAN for Substance Use Disorder

NCT07281261
Conditions
Alcohol Use Disorder, Alcohol Abuse, Substance Use Disorders, Substance Use Disorders Alcohol Use Withdrawal State
Interventions
Sparrow Ascent, Sparrow Ascent (Sham)
Device
Lead sponsor
Spark Biomedical, Inc.
Industry
Eligibility
18 Years to 64 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Conditions
Cannabis Use Disorder
Interventions
Psilocybin
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Drum-Assisted Therapy for Native Americans

NCT01356667
Conditions
Substance Use Disorders
Interventions
DARTNA, Treatment-As-Usual
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Los Angeles, California
Completed Phase 4 Interventional Accepts healthy volunteers

Depakote ER Therapy for Mania Comorbid With Substance Abuse

NCT00208195
Conditions
Bipolar Disorder, Mania, Substance Abuse, Substance Dependence
Interventions
Divalproex ER
Drug
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Omaha, Nebraska
Conditions
Behavior Therapy, Cocaine, Contingency Management, Heroin Dependence, LAAM, Opioid Dependence, Substance-Related Disorders, Alcohol & Drug Use
Interventions
LAAM
Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
21 Years to 55 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1997 – 2001
U.S. locations
1
States / cities
West Haven, Connecticut
Conditions
Potential Treatment for Alcohol Dependence-Alcohol Interaction
Interventions
PT150, Beverage
Drug · Other
Lead sponsor
Pop Test Oncology LLC
Industry
Eligibility
21 Years to 64 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Conditions
Hepatitis C, Substance Use Disorders, Substance Abuse, Intravenous
Interventions
elbasvir-grazoprevir (50 mg/100 mg)
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Portland, Oregon
Conditions
Opioid Use, Opioid Abuse
Interventions
Sociobehavioral Intervention
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Substance Abuse Disorder
Interventions
Low intensity care, Voucher reinforcement
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
223 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Stress, Drug Abuse
Interventions
Not listed
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years and older
Enrollment
373 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Mental Health
Interventions
Educational intervention
Other
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Conditions
Opioid Use, Pain, Marijuana Use
Interventions
Cannabis, Prescription Opioid Taper Support (POTS)
Drug · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Portland, Maine • Boston, Massachusetts • Cambridge, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Family-Based Drug Services for Young Disaster Victims

NCT01859000
Conditions
Substance Abuse, Families, Trauma
Interventions
Multidimensional Family Therapy, Group CBT
Other
Lead sponsor
University of Miami
Other
Eligibility
13 Years to 17 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
2
States / cities
Miami, Florida • Luling, Louisiana
Conditions
Alcoholism, Alcohol Abuse, Alcohol Dependence
Interventions
Dutasteride, Placebo
Drug
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Alcohol Use Disorder
Interventions
Cannabidiol, Placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Substance Abuse
Interventions
Contingency management
Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Depression, Alcoholism, Suicidal Behavior
Interventions
fluoxetine, bupropion
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
New York, New York
Conditions
Alcohol Abuse
Interventions
MI/Family Check-up, MI only
Behavioral
Lead sponsor
Brown University
Other
Eligibility
13 Years to 17 Years
Enrollment
208 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2008
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Substance Use Disorders, Risk Behavior, Psychiatric Disorders, Family Dysfunction
Interventions
Family Therapy based on Structural Family Therapy, Group Therapy, Psychoeducational Sessions, Individual Adolescent Therapy Sessions
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
14 Years to 17 Years
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Miami, Florida