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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: taVNS Clear all
Suspended Not applicable Interventional Accepts healthy volunteers

taVNS for Letter Learning in Dyslexia

NCT06127550
View directory record Official record
Conditions
Dyslexia
Interventions
active taVNS, sham taVNS
Device
Lead sponsor
University of Florida
Other
Eligibility
10 Years to 12 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Jul 24, 2026, 7:56 AM EDT
Recruiting Not applicable Interventional

At-home taVNS for Neurorehabilitation in Parkinson's Disease

NCT07536022
View directory record Official record
Conditions
Parkinson's Disease
Interventions
transcutaneous auricular nerve stimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
40 Years to 85 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Jul 24, 2026, 7:56 AM EDT
Recruiting Not applicable Interventional

taVNS + CCT for Neurocognitive Rehab

NCT07517237
View directory record Official record
Conditions
Psychosocial Well-being, Neurocognitive Function, Cognitive Complaint, Cognitive Dysfunction
Interventions
taVNS, Computerized Cognitive Training
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
45 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Jul 24, 2026, 7:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Noninvasive VNS to Facilitate Excitability in Motor Cortex

NCT04130646
View directory record Official record
Conditions
Stroke, Stroke Sequelae, Motor Activity
Interventions
Transcranial Magnetic Stimulation, transcutaneous auricular vagus nerve stimulation (taVNS)
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 19, 2025 · Synced Jul 24, 2026, 7:56 AM EDT
Not yet recruiting Not applicable Interventional

Effects of taVNS on Fibromyalgia Pain

NCT06193317
View directory record Official record
Conditions
Fibromyalgia, Pain
Interventions
Transauricular vagus nerve stimulation (taVNS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Jul 24, 2026, 7:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Learning and Ear Stimulation

NCT04812015
View directory record Official record
Conditions
Learning, taVNS
Interventions
transcutaneous auricular vagus nerve stimulation (taVNS) 15 minutes, taVNS 30 minutes, taVNS 45 minutes, taVNS 60 minutes, taVNS 75 minutes, taVNS 0 minutes
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Jul 24, 2026, 7:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

taVNS Cold Pressor

NCT05254080
View directory record Official record
Conditions
taVNS, Brain Stimulation
Interventions
Active taVNS, Sham taVNS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 16, 2024 · Synced Jul 24, 2026, 7:56 AM EDT
Recruiting Not applicable Interventional

Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in Chronic Kidney Disease (CKD)

NCT06927024
View directory record Official record
Conditions
Chronic Kidney Diseases
Interventions
Active taVNS, Sham taVNS
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Jul 24, 2026, 7:56 AM EDT
Completed Phase 1 Interventional

Investigating the Use of taVNS to Treat Insomnia in Individuals With Breast Cancer (taVNS-insomnia-BC)

NCT06006299
View directory record Official record
Conditions
Breast Cancer, Insomnia
Interventions
transauricular Vagus Nerve Stimulation
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Jul 24, 2026, 7:56 AM EDT
Recruiting Not applicable Interventional

taVNS for FRNS in Children

NCT05588063
View directory record Official record
Conditions
Nephrotic Syndrome in Children, Minimal Change Disease, Focal Segmental Glomerulosclerosis
Interventions
Transcutaneous auricular vagus nerve stimulation, Sham device
Device
Lead sponsor
Northwell Health
Other
Eligibility
3 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
New Hyde Park, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Jul 24, 2026, 7:56 AM EDT
Recruiting Not applicable Interventional

Home-based Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for IBS Pain

NCT06847360
View directory record Official record
Conditions
Pain, Chronic, Irritable Bowel Syndrome, Symptom Cluster
Interventions
Home-based taVNS intervention
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 29 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Jul 24, 2026, 7:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Understanding the Effects of Transauricular Vagus Nerve Stimulation on Neural Networks and Autonomic Nervous System

NCT05801809
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Transauricular vagus nerve stimulation (taVNS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 99 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Jul 24, 2026, 7:56 AM EDT
Completed Not applicable Interventional

Effect of Daily Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on Proteinuria in Pediatric Patients With Idiopathic Nephrotic Syndrome

NCT04169776
View directory record Official record
Conditions
Idiopathic Nephrotic Syndrome, Frequently Relapsing Nephrotic Syndrome
Interventions
Transcutaneous Auricular Vagus Nerve (taVNS) stimulation
Device
Lead sponsor
Northwell Health
Other
Eligibility
2 Years to 21 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Sep 27, 2022 · Synced Jul 24, 2026, 7:56 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Trans Auricular Vagus Nerve Stimulation (taVNS) and Robotic Training for Paralyzed Arm After Stroke

NCT05339893
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
In Motion Rehabilitation Robot
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 85 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 20, 2023 · Synced Jul 24, 2026, 7:56 AM EDT
Recruiting Not applicable Interventional

sTMS Combined With CIMT and taVNS In Infants With Hemiplegia

NCT07063446
View directory record Official record
Conditions
Hemiplegia, Perinatal Brain Injury
Interventions
sTMS, taVNS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
8 Months to 24 Months
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Jul 24, 2026, 7:56 AM EDT
Completed Not applicable Interventional

taVNS on the Inpatient Psychiatric Unit

NCT05791383
View directory record Official record
Conditions
Depression, Anxiety
Interventions
transcutaneous auricular neurostimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 5, 2025 · Synced Jul 24, 2026, 7:56 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effect of (TaVNS) on Anxiety and Brain Function in Distressed Health Care Workers

NCT05132881
View directory record Official record
Conditions
Anxiety, Distress, Emotional, Effects of Vibration, Healthy
Interventions
Neuvana 2.0 Transcutaneous Auricular Vagal Nerve Stimulation (TaVNS), Waitlist Control, Healthy Controls: Substudy Group III, Distressed Workers: Subgroup II
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
21 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Jul 24, 2026, 7:56 AM EDT
Recruiting Not applicable Interventional

At-Home taVNS - Stroke Rehab

NCT06616831
View directory record Official record
Conditions
Stroke, Stroke, Ischemic, Stroke Hemorrhagic
Interventions
Remote Transcutaneous Auricular Vagal Nerve Stimulation Paired with Task-Specific Training
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 19, 2025 · Synced Jul 24, 2026, 7:56 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

The ENHANCE Study: taVNS and Psilocybin

NCT05866471
View directory record Official record
Conditions
Healthy, Psychedelic Experiences, Vagus Nerve Stimulation
Interventions
Psilocybin, Transcutaneous auricular Vagus Nerve Stimulation (taVNS), Psychosocial Support Alone, Sham taVNS
Drug · Device · Behavioral + 1 more
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 70 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Jul 24, 2026, 7:56 AM EDT
Recruiting Not applicable Interventional

Self-applied taVNS for CIPN

NCT07596030
View directory record Official record
Conditions
Chemotherapy Induced Peripheral Neuropathy
Interventions
Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Jul 24, 2026, 7:56 AM EDT
Recruiting Not applicable Interventional

taVNS for Breast Cancer Pain and Symptom Management

NCT07500012
View directory record Official record
Conditions
Breast Cancer Survivors
Interventions
Active taVNS, Sham taVNS
Device
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 79 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Jul 24, 2026, 7:56 AM EDT
Recruiting Not applicable Interventional

EEG Changes and DNA Markers Related to taVNS in Stroke Patients: a Preliminary Study

NCT06226493
View directory record Official record
Conditions
Stroke
Interventions
Transcutaneous vagus nerve stimulation
Device
Lead sponsor
Casa Colina Hospital and Centers for Healthcare
Other
Eligibility
18 Years to 80 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Jul 24, 2026, 7:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Combined Effect of TENS and TaVNS on Pressure and Heat Pain Thresholds in Pain-Free Subjects

NCT06361381
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Active Transcutaneous Auricular Vagus Nerve Stimulation (TaVNS), Placebo Transcutaneous Auricular Vagus Nerve Stimulation (TaVNS), Transcutaneous Electrical Nerve Stimulation
Device
Lead sponsor
University of Hartford
Other
Eligibility
18 Years to 40 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
West Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Jul 24, 2026, 7:56 AM EDT
Completed Early Phase 1 Interventional Results available

CIMT and taVNS for Hemiplegia in Infants

NCT05101707
View directory record Official record
Conditions
Infant Development, Hemiplegia, Constraint Induced Movement Therapy
Interventions
transcutaneous auricular vagus nerve stimulation, Constraint induced movement therapy
Device · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
6 Months to 18 Months
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Jul 24, 2026, 7:56 AM EDT