Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 1, 2026, 3:15 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Type1diabetes, Low Carbohydrate Diet
Interventions
low carbohydrate diet, standard carbohydrate diet
Other
Lead sponsor
Yale University
Other
Eligibility
12 Years to 21 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Type1diabetes
Interventions
Insulin pump
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
6 Years to 18 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Type1diabetes
Interventions
Mobile application
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
New Haven, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers

Gluten and Amylase Trypsin Inhibitors (ATI) Free Diet

NCT03443180
Conditions
Type1diabetes
Interventions
Gluten and Amylase Trypsin Inhibitors (ATI)-free diet
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
2 Years to 23 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

IN Insulin in Type 1 Diabetes (T1D) Hypoglycemia Unawareness: Safety Only Phase

NCT04028960
Conditions
Type1diabetes
Interventions
Regular insulin (Humulin-R), intranasal route, SipNose intranasal device
Drug · Device
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Completed Early Phase 1 Interventional Results available

Adrenergic System in Islet Transplantation

NCT03079921
Conditions
Type1diabetes, Hypoglycemia, Hypoglycemia Unawareness, Islet Cell Transplantation
Interventions
Phentolamine, Propranolol, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Type1diabetes
Interventions
Education: Session 1 - Basics of type 1 management, Session 2 - Carbohydrate counting, Education: Session 3 - Insulin self- adjustment, Education: Session 4 - Sick day rules and physical activity dose adjustments, Education: Session 5 - Starting the insulin pen (for pen users) or pump (for pump users), Education: Session 6 - Trouble shooting the pump (for pump users)
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 75 Years
Enrollment
63 participants
Timeline
2017 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Recruiting Not applicable Interventional Accepts healthy volunteers

Thrive With Type 1 Diabetes 2026

NCT07522866
Conditions
Type1diabetes
Interventions
TranS-C Intervention Arm, Attention Control Enhanced Usual Care (EUC) Arm
Behavioral
Lead sponsor
Emory University
Other
Eligibility
31 Years to 75 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
2
States / cities
Atlanta, Georgia
Completed Not applicable Interventional Results available

Hybrid Closed Loop Insulin Delivery System in Hypoglycemia

NCT03215914
Conditions
Type1diabetes, Hypoglycemia Unawareness, Nocturnal Hypoglycemia, Hypoglycemia Night, Hypoglycemia
Interventions
MiniMed 670G system
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
25 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
3
States / cities
Philadelphia, Pennsylvania
Conditions
Diabetes, Diabetes Mellitus, Type 1, Type1diabetes, Diabetes Mellitus
Interventions
YG1699, Dapagliflozin
Drug
Lead sponsor
Youngene Therapeutics Inc., Ltd.
Industry
Eligibility
18 Years to 60 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chula Vista, California
Conditions
Type1diabetes
Interventions
CB Sleep
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 40 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Type1diabetes
Interventions
4T Education and Care
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
6 Months to 21 Years
Enrollment
316 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Steamboat Springs, Colorado
Completed Not applicable Interventional Accepts healthy volunteers

Type 1 Teamwork: A Tool for Parents of Adolescents With Type 1 Diabetes

NCT04073914
Conditions
Type1diabetes, Type1 Diabetes Mellitus
Interventions
Type 1 Teamwork Program
Behavioral
Lead sponsor
Carelon Research
Other
Eligibility
Not listed
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
2
States / cities
New Haven, Connecticut • Watertown, Massachusetts
Active, not recruiting Phase 2 Interventional

Probiotics in Newly Diagnosed T1D

NCT04141761
Conditions
Type 1 Diabetes, Type1diabetes, Type 1 Diabetes Mellitus
Interventions
Visbiome, Placebo
Dietary Supplement · Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
5 Years to 17 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Type1diabetes
Interventions
Artificial Pancreas Controller in Dual Hormone Mode, Artificial Pancreas Controller in Single Hormone Mode, Artificial Pancreas Controller in Predictive Low Glucose Suspend Mode, XeriSol glucagon
Device · Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
21 Years to 50 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Portland, Oregon
Completed Not applicable Interventional Accepts healthy volunteers

Modulation of Type 1 Diabetes Susceptibility Through the Use of Probiotics

NCT03423589
Conditions
Type1diabetes, Type1 Diabetes Mellitus
Interventions
VSL#3
Dietary Supplement
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
5 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
type1diabetes
Interventions
BREATHE-T1D
Behavioral
Lead sponsor
Children's National Research Institute
Other
Eligibility
12 Years to 17 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Completed Not applicable Interventional Results available

A Sleep Intervention in Type 1 Diabetes

NCT03617770
Conditions
Short Sleep Phenotype, Type1diabetes
Interventions
Sleep Opt-In, Healthy Living
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Chicago, Illinois
Completed No phase listed Observational Accepts healthy volunteers

Skeletal Fragility in Type 1 Diabetes: Glycemic Control and Bone Strength

NCT04289727
Conditions
Type1diabetes
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
8 Years to 14 Years
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
New York, New York
Conditions
Type1diabetes
Interventions
Aspart insulin
Drug
Lead sponsor
Yale University
Other
Eligibility
9 Years to 15 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Completed Not applicable Interventional Results available

Iterative Beta Testing of Videos for the DIPPer Academy

NCT03385265
Conditions
Type1diabetes
Interventions
DIPPer Academy, Standard of Care
Behavioral · Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
3 Years to 65 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Kansas City, Kansas • Kansas City, Missouri
Conditions
Type 1 Diabetes, type1diabetes, Type 1 Diabetes Mellitus
Interventions
Lactiplantibacillus plantarum, Placebo
Dietary Supplement · Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
3 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Type1diabetes
Interventions
MyT1DHero, Other T1D Mobile App
Device
Lead sponsor
Michigan State University
Other
Eligibility
10 Years to 15 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
East Lansing, Michigan
Conditions
Type1diabetes
Interventions
Positive Psychology Intervention, Education
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
13 Years to 17 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee