Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 17, 2026, 7:25 AM EDT

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Showing 1489–1512 of 5,021 matching trials from the live ClinicalTrials.gov search.
Conditions
Tourniquet Hypertension, Intraoperative Hypertension, Total Ankle Arthroplasty, Ankle Fusion
Interventions
Mepivacaine, Saline, Perifemoral Injection of Local Anesthetic
Drug · Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Aphasia
Interventions
Aphasia identification (ID) card
Behavioral
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
18 Years to 59 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Springfield, Massachusetts
Conditions
Healthy Participants
Interventions
S-892216-LAI, Placebo
Drug
Lead sponsor
Shionogi
Industry
Eligibility
18 Years to 55 Years
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
3
States / cities
Cypress, California • Lenexa, Kansas • Salt Lake City, Utah
Conditions
Situational Anxiety
Interventions
Botanical extract for anxiety, Placebo capsule
Dietary Supplement
Lead sponsor
PLT Health Solutions
Industry
Eligibility
18 Years to 60 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
San Francisco, California
Conditions
Pleural Infection
Interventions
Saline Irrigation
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Recruiting No phase listed Observational Accepts healthy volunteers

Cancer in Inherited Bone Marrow Failure Syndromes

NCT00027274
Conditions
Diamond Blackfan Anemia, Dyskeratosis Congenita, Fanconi Anemia, Shwachman Diamond Syndrome, Inherited Bone Marrow Failure Syndrome, Aplastic Anemia
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
1 Day to 100 Years
Enrollment
4,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2001
U.S. locations
2
States / cities
Bethesda, Maryland • Rockville, Maryland
Recruiting Not applicable Interventional Accepts healthy volunteers

OCT Vibrography for Biomechanical Properties of Tissues

NCT05759780
Conditions
Cornea, Skin Diseases, Gingival Diseases
Interventions
Optical imaging of the tissues
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Metabolic Disease, Propionic Acidemia, Organic Acidemia
Interventions
Not listed
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
1 Month to 100 Years
Enrollment
1,045 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2036
U.S. locations
2
States / cities
Bethesda, Maryland • Pittsburgh, Pennsylvania
Recruiting No phase listed Observational Accepts healthy volunteers

Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer

NCT05732623
Conditions
Colorectal Cancer, Early Onset Colorectal Cancer, Diet Habit, Risk Reduction
Interventions
Semi Quantitative Food Frequency Questionnaire (SQFFQ)
Behavioral
Lead sponsor
San Raffaele University
Other
Eligibility
18 Years to 49 Years
Enrollment
2,300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2035
U.S. locations
2
States / cities
Denver, Colorado • Chicago, Illinois
Recruiting No phase listed Observational Accepts healthy volunteers

Residual Gastric Content and GLP-1

NCT06814080
Conditions
Pre-op Gastric Emptying
Interventions
Not listed
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Little Rock, Arkansas
Recruiting Not applicable Interventional Accepts healthy volunteers

Examining the Role of Female Endogenous Sex Hormones in Eccentric Exercise

NCT05934708
Conditions
Inflammatory Response
Interventions
Eccentric leg extension
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Recruiting Not applicable Interventional Accepts healthy volunteers

Uncertainty and Firearms: Obtaining Secure Storage

NCT05818696
Conditions
Anxiety
Interventions
Lethal Means Counseling (LMC), CBT for Uncertainty - Enhanced (CUE)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Recruiting Not applicable Interventional Accepts healthy volunteers

Neural and Psychological Mechanisms of Pain Perception

NCT02446262
Conditions
Pain, Normal Physiology, Healthy Volunteers
Interventions
Instructions, Attention, Thermal Pain, Placebo instructions
Behavioral
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years to 50 Years
Enrollment
550 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Recruiting Not applicable Interventional Accepts healthy volunteers

Ultrasound for Healthy Aging

NCT07168525
Conditions
Aging
Interventions
Ultrasound spa, Sham ultrasound spa
Device · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
70 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Antonio, Texas
Recruiting Not applicable Interventional Accepts healthy volunteers

Targeting Breathing Limitations to Improve Functional Outcomes in HFpEF

NCT05723679
Conditions
Heart Failure With Preserved Ejection Fraction, Obesity
Interventions
HeO2 gas mixture, Room air gas mixture
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
55 Years to 90 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
Dallas, Texas
Recruiting No phase listed Observational Accepts healthy volunteers

In Vivo Metabolic Profiling of CLL (Chronic Lymphocytic Leukemia)

NCT04785989
Conditions
Chronic Lymphocytic Leukemia
Interventions
[U-13C]glucose, [13C5]glutamine
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Recruiting No phase listed Observational Accepts healthy volunteers

Role of Transposable Elements in Septic Immune Aging

NCT06809868
Conditions
Sepsis, Sepsis and Septic Shock, Sepsis With Multiple Organ Dysfunction (MOD), Sepsis With Acute Organ Dysfunction, Sepsis, Severe, Sepsis at Intensive Care Unit, Sepsis, Severe Sepsis and Septic Shock, Sepsis, Septic Shock
Interventions
RNA and DNA Sequencing
Genetic
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Francisco, California
Recruiting Not applicable Interventional Accepts healthy volunteers

BASIS-T Efficacy Trial

NCT05989568
Conditions
Behavior, Child
Interventions
BASIS-T, Attention Control (ACC)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
276 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Recruiting No phase listed Observational Accepts healthy volunteers

DeBakey Cardiovascular Magnetic Resonance Study

NCT04281823
Conditions
Cardiovascular Diseases
Interventions
Cardiovascular Magnetic Resonance
Diagnostic Test
Lead sponsor
Dipan Shah
Other
Eligibility
Not listed
Enrollment
100,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2058
U.S. locations
1
States / cities
Houston, Texas
Conditions
Anxiety Disorders and Symptoms, Fibromyalgia, Arthritis, Chronic Pain, Hypertension,Essential
Interventions
IV Vitamin Infused Therapy Treatment, Herbal medicine
Dietary Supplement · Drug
Lead sponsor
Faith A. Richardson
Other
Eligibility
21 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Dover, Delaware
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating the Effectiveness of the Health App Recommendation Tool

NCT07216716
Conditions
Alzheimers Disease Related Dementias
Interventions
Health App Recommendation Tool (HART)
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Recruiting Not applicable Interventional Accepts healthy volunteers

Cognition and Ultrasound

NCT07220655
Conditions
Healthy Participants
Interventions
Low-Intensity Focused Ultrasound (FUS or LIFU)
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Health Services Research
Interventions
Performance Coaching
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 64 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Conditions
Obstructive Sleep Apnea
Interventions
Slow Wave UASD
Device
Lead sponsor
Slow Wave, Inc.
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Austin, Texas