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Showing 2257–2280 of 5,024 matching trials from the local directory fallback.
Recruiting Not applicable Interventional Accepts healthy volunteers

Stimulation-Based Modulation of Spinal and Cortical Sensory Pathways

NCT07401186
Conditions
Able Bodied, Stroke
Interventions
Bipolar Neural Stimulation Electrode
Device
Lead sponsor
Peter C. Gerszten, MD
Other
Eligibility
21 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Recruiting No phase listed Observational Accepts healthy volunteers

Functional Ovarian Reserve in Sickle Cell Disease

NCT07392216
Conditions
Sickle Cell Disease
Interventions
Not listed
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
10 Years to 18 Years · Female only
Enrollment
440 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2034
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Low Milk Supply
Interventions
Pumping frequency intervention
Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 45 Years
Enrollment
225 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, New York
Conditions
Smoking Cessation, Tobacco-Related Carcinoma
Interventions
Focus Group, Interview, Silicone Wrist Band, Smoking cessation education, Survey Administration, Telephone-Based Intervention, Urine Specimen Collection
Other · Behavioral · Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
760 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Francisco, California
Conditions
Dating Violence, Parent, Primary Care
Interventions
Engaging Together for Health Relationships
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Monongahela, Pennsylvania
Recruiting Not applicable Interventional Accepts healthy volunteers

Adaptation of the Family Check-Up Online

NCT07025083
Conditions
Substance Use (Drugs, Alcohol)
Interventions
Adapted Family Check-Up Online, Original Family Check-Up Online
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
11 Years to 14 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Eugene, Oregon
Recruiting Phase 2 Interventional Accepts healthy volunteers

Allo HSCT for High Risk Hemoglobinopathies

NCT06872333
Conditions
Graft Failure, Hemoglobinopathies, Sickle Cell Disease
Interventions
Alemtuzumab, Busulfan, Cell Infusion, Cyclophosphamide, Fludarabine, Mycophenolate Mofetil, Plerixafor (mozobil), Sirolimus, Tacrolimus, Thymoglobulin, Total Body Irradiation
Drug · Biological · Radiation
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
Up to 55 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2032
U.S. locations
1
States / cities
Minneapolis, Minnesota
Recruiting No phase listed Observational Accepts healthy volunteers

Aquagenic Wrinkling Prediction

NCT06831110
Conditions
Aquagenic Wrinkling of Palms, Carrier State
Interventions
Aquagenic Wrinkling
Procedure
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 24 Years
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Recruiting No phase listed Observational Accepts healthy volunteers

Physical and Cognitive Aging Study in Older Adults

NCT06726616
Conditions
Aging, Healthy, Cognitive Aging, Exercise, Hispanic Americans, Older Adults (65 Years and Older)
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
55 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Conditions
Interaction
Interventions
Drug cocktail, Oregano
Drug · Dietary Supplement
Lead sponsor
Washington State University
Other
Eligibility
18 Years to 64 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Spokane, Washington
Conditions
Interaction
Interventions
Cannabidiol in the form of hemp, Clopidogrel
Drug
Lead sponsor
Washington State University
Other
Eligibility
21 Years to 64 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Spokane, Washington
Conditions
Alzheimer Disease, Healthy
Interventions
LY4006895, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
45 Years to 85 Years
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
11
States / cities
Los Alamitos, California • Lady Lake, Florida • Maitland, Florida + 8 more
Conditions
Healthy Participants With Lower-than-average Mental Well-being
Interventions
Context 1, Context 2, Placebo, Psilocybin
Behavioral · Drug
Lead sponsor
Robin Carhart-Harris, PhD, MA
Other
Eligibility
21 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
San Francisco, California
Recruiting Not applicable Interventional Accepts healthy volunteers

Diaphragmatic Breathing for the Treatment of Bloating and Distension

NCT06596759
Conditions
Bloating
Interventions
Diaphragmatic Breathing
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Jacksonville, Florida
Recruiting Not applicable Interventional Accepts healthy volunteers

Spinal Networks of Balance Learning and Retention in Older Adults

NCT06517043
Conditions
Aging
Interventions
Balance Training, Spinal Active tsDCS, Spinal Sham tsDCS
Behavioral · Device
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 95 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Recruiting Not applicable Interventional Accepts healthy volunteers

Craving & Decision-Making

NCT06440577
Conditions
Decision Making
Interventions
Audio-visual stimuli (Drug), Audio-visual stimuli (Food), Audio-visual stimuli (Neutral-Relaxing), Audio-visual stimuli (Non-Food)
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Piscataway, New Jersey
Conditions
Memory
Interventions
nap
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
36 Months to 60 Months
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
2
States / cities
College Park, Maryland • Amherst, Massachusetts
Recruiting Phase 3 Interventional Accepts healthy volunteers

Buprenorphine for Individuals in Jail

NCT06306443
Conditions
Opioid Use Disorder
Interventions
extended-release buprenorphine (XR-B)
Drug
Lead sponsor
Friends Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Baltimore, Maryland
Recruiting Not applicable Interventional Accepts healthy volunteers

Gut Microbiota-Mediated Inflammatory Interactions Between AUD and HIV Infection

NCT06139224
Conditions
Alcohol Use Disorder, Human Immunodeficiency Virus
Interventions
4 week placebo consumption, 4 week prebiotic consumption
Other · Dietary Supplement
Lead sponsor
Rush University Medical Center
Other
Eligibility
45 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Recruiting Not applicable Interventional Accepts healthy volunteers

CONVIVO Endomicroscopy

NCT06087393
Conditions
Brain Tumor
Interventions
CONVIVO
Device
Lead sponsor
Northwell Health
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Manhasset, New York
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Contribution of UGT2B17 to the Pharmacokinetics of Diclofenac

NCT06053411
Conditions
Interaction
Interventions
Diclofenac, curcumin
Drug · Dietary Supplement
Lead sponsor
Washington State University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Spokane, Washington
Conditions
ATTR Amyloidosis Wild Type, ATTR Gene Mutation, ATTRV122I Amyloidosis, Cardiac Amyloidosis, Cardiomyopathy, Hypertrophic, Lumbar Spinal Stenosis
Interventions
Tc99-PYP or Tc99-HDMP Scan
Diagnostic Test
Lead sponsor
Columbia University
Other
Eligibility
50 Years and older
Enrollment
1,663 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
6
States / cities
Beverly Hills, California • Boston, Massachusetts • Rochester, Minnesota + 2 more
Conditions
Cesarean Delivery, General Anesthesia
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
15 Years to 55 Years · Female only
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
34
States / cities
Little Rock, Arkansas • San Francisco, California • Stanford, California + 29 more
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Attentional Mechanisms in SCD

NCT06002477
Conditions
Subjective Cognitive Decline
Interventions
Mecamylamine Challenge, Placebo Comparator Challenge
Drug · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
55 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Nashville, Tennessee