- Conditions
- Insulin Resistance, Non-Alcoholic Fatty Liver Disease, Overweight and Obesity, Prediabetic State
- Interventions
- Alpelisib 300 mg, Mixed Meal Tolerance Test, Nestlé BOOST Plus, Placebo, [1-13C] sodium acetate, [6,6-2H2] D-glucose
- Drug · Diagnostic Test · Dietary Supplement
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- New York, New York
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Showing 1–2
of 2
matching trials from the local directory fallback.
- Conditions
- Hyperinsulinemia, Insulin Resistance, Metabolic Dysfunction Associated Steatotic Liver Disease, Non-Alcoholic Fatty Liver Disease, Obesity, Prediabetic State
- Interventions
- 20% D-glucose (aq), Glucagon, Growth Hormone, Human, Harvard Apparatus PHD ULTRA CP syringe pump, Insulin human, KIND Bar, Nestle BOOST Plus, Octreotide Acetate, Yellow Springs Instruments (YSI) 2500 Biochemistry Glucose/Lactate Analyzer, [1-13C1] sodium acetate, [6,6-2H2] D-glucose
- Drug · Device · Dietary Supplement + 1 more
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2027 – 2029
- U.S. locations
- 1
- States / cities
- New York, New York