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ClinicalTrials.gov public records Last synced Nov 8, 2026, 9:35 AM EST

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Showing 1–24 of 211 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: 1-Session Exposure Therapy Clear all

Conditions: Stress Disorders, Post-Traumatic
Interventions: Cognitive behavioral therapy (CBT), Educational session and treatment as usual; Behavioral
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 21 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 2
States / cities: New York, New York • Queens, New York

Conditions: Anxiety
Interventions: Mayo Clinic Anxiety Coach, Treatment as Usual; Device · Other
Lead sponsor: Stephen Whiteside; Other
Eligibility: 7 Years to 17 Years
Enrollment: 145 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Elevated Anxiety Sensitivity
Interventions: Standard Exposure, Stress Management Training, Enhanced Exposure; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years to 70 Years
Enrollment: 399 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 5
States / cities: Boulder, Colorado • Miami, Florida • Boston, Massachusetts + 2 more

Conditions: Diabetic Foot, Diabetic Foot Ulcer, Diabetes, Diabetes Mellitus, Infected Wound, Infected Ulcer of Skin
Interventions: Phototherapy, Debridement Surgery and Wound Dressing; Device · Procedure
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: HIV, Depression, Pain
Interventions: HIVPASS, Health Education; Behavioral
Lead sponsor: Butler Hospital; Other
Eligibility: 18 Years and older
Enrollment: 187 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 4
States / cities: Boston, Massachusetts • Minneapolis, Minnesota • Providence, Rhode Island

Conditions: Posttraumatic Stress Disorder, Substance Use Disorder, Alcohol Use Disorder
Interventions: Creating Change (CC), Seeking Safety (SS); Behavioral
Lead sponsor: VA Boston Healthcare System; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression, Major Depressive Disorder, Dysthymic Disorder, Depressive Symptoms, Cardiovascular Diseases, Heart Diseases, Coronary Artery Disease, Stroke
Interventions: Beating the Blues (BtB), Problem Solving Treatment in Primary Care (PST-PC), Antidepressant Medications, Usual Care; Behavioral · Drug · Other
Lead sponsor: Indiana University; Other
Eligibility: 50 Years and older
Enrollment: 216 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Physical Inactivity, Vascular Dysfunction, Skeletal Muscle Atrophy
Interventions: Sauna, Reduced Physical Activity; Device · Behavioral
Lead sponsor: Brigham Young University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Provo, Utah

Conditions: Hypertension, Stress, Cardiovascular Diseases
Interventions: MBCT-T, Usual Care; Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older · Female only
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Anxiety
Interventions: Mayo Clinic Anxiety Coach; Device
Lead sponsor: Stephen Whiteside; Other
Eligibility: 7 Years to 17 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: PTSD, Marital Relationship
Interventions: CBCT for PTSD, Prolonged Exposure; Behavioral
Lead sponsor: Toronto Metropolitan University; Other
Eligibility: 18 Years and older
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 3
States / cities: Fort Hood, Texas • Fort Sam Houston, Texas • San Antonio, Texas

Conditions: Obsessive-compulsive Disorders and Symptoms
Interventions: ACT-Focused ERP, TAU-ERP; Behavioral
Lead sponsor: Mclean Hospital; Other
Eligibility: 18 Years and older
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2019
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Eating Disorders, Anorexia Nervosa, Anorexia Nervosa in Remission
Interventions: Facing Eating Disorder Fears Condition; Behavioral
Lead sponsor: University of Louisville; Other
Eligibility: 18 Years to 65 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Spinal Cord Injuries
Interventions: Daily acute intermittent hypoxia, Walking + tSTIM; Other · Device
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Jacksonville, Florida • Cambridge, Massachusetts

Conditions: Specific Phobia
Interventions: Exposure therapy; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Opioid Use Disorder, Chronic Pain
Interventions: Steps 2 Change (S2C), Control; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Fear of Flying
Interventions: Virtual Reality Exposure Therapy; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 89 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Posttraumatic Stress Disorder, PTSD
Interventions: Trauma Affect Regulation: Guide for Education and Therapy, Present Centered Therapy (PCT) - psychotherapy, No-treatment "waitlist" group; Behavioral · Other
Lead sponsor: UConn Health; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 147 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 2
States / cities: Farmington, Connecticut • Hartford, Connecticut

Conditions: Cancer, Tumor, Solid, Cancer, Lung, Cancer, Bone, Metastasis to Lung, Metastasis to Bone
Interventions: RMRS IDE Device; Device
Lead sponsor: RefleXion Medical; Industry
Eligibility: 22 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 2
States / cities: Stanford, California • Dallas, Texas

Conditions: Specific Phobia
Interventions: EXP, EXP + SBF, EXP + SBF + AA; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years to 65 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), Separation Anxiety Disorder, Specific Phobia, Obsessive Compulsive Disorder (OCD), Panic Disorder (With or Without Agoraphobia)
Interventions: Relaxation and Mentorship Training (RMT), Stepped Care Targeting Exposure and Parenting for Anxiety (STEP-A); Behavioral
Lead sponsor: Andrew Wiese; Other
Eligibility: 7 Years to 17 Years
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Social Anxiety Disorder
Interventions: Cognitive Behavioral Group Therapy (CBGT), D-Cycloserine, Placebo; Behavioral · Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 169 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: End Stage Renal Failure
Interventions: Lower sodium intervention, Progressive Challenge to Post Dialysis Weight; Behavioral · Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 85 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 2
States / cities: Ann Arbor, Michigan • Livonia, Michigan

Conditions: Posttraumatic Stress Disorder
Interventions: 1-Session Exposure Therapy, 3-Session Exposure Therapy; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Atlanta, Georgia

Search by objective public record fields.

Safety and Efficacy of Cognitive Behavior Therapy for People With Post-traumatic Stress and Cardiovascular Illness

Youth Mayo Clinic Anxiety Coach Randomized Controlled Trial

Exposure Therapy Consortium (ETC) for Anxiety Sensitivity

Adjunctive Phototherapy Treatment of Infected Diabetic Ulcers

Treating Comorbid Pain and Depression in HIV+ Individuals

Present- Versus Past-focused Therapy for PTSD and Substance Use Disorder

eIMPACT Trial: Modernized Collaborative Care to Reduce the Excess CVD Risk of Older Depressed Patients

Heat Therapy During Reduced Physical Activity

Stress Management to Support Women's Health

Youth Mayo Clinic Anxiety Coach Pilot Study

Individual PE vs Couples' CBT for Combat-Related Posttraumatic Stress Disorder

Assessing Models of Exposure Therapy

Facing Eating Disorder Fears for Anorexia Nervosa

Low Oxygen Therapy to Enhance Walking Recovery After SCI.

The Effects of Safety Seeking Behaviors During Exposure Therapy for Adults With Spider Phobia

An Adaptive Walking Intervention to Manage Chronic Pain in Veterans With Opioid Use Disorder Engaged in Opioid Agonist Treatment

Targeting Reconsolidation to Prevent Return of Fear

Mothers Overcoming and Managing Stress

Performance and Safety of Biology-Guided Radiotherapy Using the RefleXion Medical Radiotherapy System (BIOGUIDE-X)

Anti-phobic and Safety Behaviors in the Treatment of Acrophobia

Stepped Care Treatment for Anxiety Resilience

D-Cycloserine Enhancement of Exposure in Social Phobia

Volume,Sodium and Blood Pressure Management in HD

Optimal Dose of Early Intervention to Prevent PTSD