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Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: 1064nm Laser Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of a Novel Microlens Array Device for Skin Rejuvenation

NCT02888626
View directory record Official record
Conditions
Wrinkles, Scars
Interventions
Microlens Array
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
20 Years to 75 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Brisbane, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Sep 6, 2026, 10:13 AM EDT
Completed Not applicable Interventional Results available

PicoWay™ 730 Resolve Fusion for Benign Pigmented Lesions and Wrinkles

NCT03774849
View directory record Official record
Conditions
Benign Pigmented Lesions, Facial Wrinkles
Interventions
PicoWay™ 532nm fractional handpiece, PicoWay™ 730nm wavelength, PicoWay™ 1064nm fractional handpiece
Device
Lead sponsor
Candela Corporation
Industry
Eligibility
21 Years to 80 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Wayland, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced Sep 6, 2026, 10:13 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Subject Evaluation of a 1064nm Diode Laser/RF

NCT04090853
View directory record Official record
Conditions
Subcutaneous Fat Disorder
Interventions
Venus Bliss
Device
Lead sponsor
Venus Concept
Industry
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
3
States / cities
Denver, Colorado • Foxborough, Massachusetts • Woodmere, New York
Source: ClinicalTrials.gov public record
Updated May 7, 2023 · Synced Sep 6, 2026, 10:13 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Clinical Evaluation to Assess the Safety and Efficacy of GentleMax Pro™/GentleMax Pro Plus™

NCT04975243
View directory record Official record
Conditions
Unwanted Fine Facial Hair
Interventions
GentleMax Pro Plus 755nm and 1064nm laser system
Device
Lead sponsor
Candela Corporation
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Marlborough, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Sep 6, 2026, 10:13 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluate the Performance of the PicoWayTM Picosecond Fractional Laser for Wrinkles Reduction

NCT02600104
View directory record Official record
Conditions
Unwanted Wrinkles
Interventions
PicoWayTM
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years to 75 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
4
States / cities
Chicago, Illinois • New York, New York • Ardmore, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 3, 2017 · Synced Sep 6, 2026, 10:13 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Performance of PicoWayTM Picosecond Fractional Laser for Acne Scars

NCT02592993
View directory record Official record
Conditions
Acne Scars - Mixed Atrophic and Hypertrophic
Interventions
PicoWay device
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years to 75 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
3
States / cities
Chicago, Illinois • New York, New York • Ardmore, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 22, 2017 · Synced Sep 6, 2026, 10:13 AM EDT
Completed Not applicable Interventional

Evaluation of the Safety and Precursors of Efficacy

NCT02098811
View directory record Official record
Conditions
Subcutaneous Fat
Interventions
1064nm Laser, 940nm Laser
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
20 Years to 55 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Staten Island, New York
Source: ClinicalTrials.gov public record
Updated Oct 26, 2020 · Synced Sep 6, 2026, 10:13 AM EDT
Completed Phase 1 Interventional

Tolerability of Device Based Therapies for Neurofibromatosis Type 1 Cutaneous Neurofibromas

NCT04730583
View directory record Official record
Conditions
Cutaneous Neurofibroma
Interventions
Kybella, 1064nm laser, 755nm Alexandrite Laser
Drug · Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 20, 2025 · Synced Sep 6, 2026, 10:13 AM EDT
Terminated Not applicable Interventional

Revlite Laser System Compared to the Candela Alex TriVantage System Refractory Mixed Type Melasma

NCT01745224
View directory record Official record
Conditions
Melasma
Interventions
Revlite Q switched Nd:YAG, Trivantage Q switched Nd: YAG
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 3, 2020 · Synced Sep 6, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy and Safety of PiQo4 Device for Treatment of Melasma

NCT03565341
View directory record Official record
Conditions
Melasma
Interventions
PiQo4
Device
Lead sponsor
Focus Medical, LLC
Industry
Eligibility
18 Years to 75 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 26, 2019 · Synced Sep 6, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Histological Study to Evaluate Skin Changes After PicoWay® 1064 nm and 532nm Picosecond Fractional Laser Treatment

NCT02700204
View directory record Official record
Conditions
Dyschromia
Interventions
PicoWay 532nm fractional treatment, PicoWay 1064nm fractional treatment
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years to 75 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 1, 2016 · Synced Sep 6, 2026, 10:13 AM EDT
Enrolling by invitation Phase 2 Interventional Accepts healthy volunteers

Treatment of Sebaceous Hyperplasia With PDL and Nd:YAG Versus Erbium:YAG: A Randomized Controlled Trial

NCT04429607
View directory record Official record
Conditions
Sebaceous Hyperplasia
Interventions
Erbium:YAG Laser, Pulsed Dye Laser, Nd:YAG Laser, Electrodessication and curettage
Device · Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 6, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Laser 360iQ: Optimal Light-laser Combination Therapy

NCT04519723
View directory record Official record
Conditions
Photodamage
Interventions
Assess the safety and efficacy of light-laser therapy using the Harmony XL and Dye-VL (500-600nm), Q-Switched 1064nm, Er:YAG 2940nm modules in combination .
Device
Lead sponsor
Alma Lasers Inc.
Industry
Eligibility
35 Years to 60 Years · Female only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Edina, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Sep 6, 2026, 10:13 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Effects of Low-Level Laser Stimulation With and Without Fear Extinction Training

NCT02926352
View directory record Official record
Conditions
Phobias, Claustrophobia, Social Phobia
Interventions
Extinction Training, Low-Level Laser Therapy, Sham Low-Level Laser Therapy
Behavioral · Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 27, 2022 · Synced Sep 6, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Low Fluence 1064nm Laser Hair Reduction for Pseudofolliculitis Barbae in Skin Types IV, V, VI

NCT00402129
View directory record Official record
Conditions
Pseudofolliculitis Barbae
Interventions
1064nm Nd:YAG laser at 12 J/cm2, 20 ms and 10mm spot size.
Procedure
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 21, 2006 · Synced Sep 6, 2026, 10:13 AM EDT
Completed Not applicable Interventional Results available

Multiplex Laser vs. PDL (Pulsed Dye Laser ) in the Treatment of Surgical Scars

NCT02472405
View directory record Official record
Conditions
Scar
Interventions
595/1064nm Multiplex Laser, 595nm PDL
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 90 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 20, 2018 · Synced Sep 6, 2026, 10:13 AM EDT
Completed Not applicable Interventional Results available

Evaluation of the Candela 1064nm:Nd:YAG Laser for Skin Tightening

NCT00585715
View directory record Official record
Conditions
Localized Lipodystrophy
Interventions
1064 nm Nd:YAG laser
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
40 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
2
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 20, 2022 · Synced Sep 6, 2026, 10:13 AM EDT
Completed Phase 1 Interventional

Efficacy of Skin Cooling in Reducing Pain Associated With Non-invasive Treatments of Neurofibromatosis Type 1 Cutaneous Neurofibromas

NCT06132165
View directory record Official record
Conditions
Neurofibromatosis 1
Interventions
Deoxycholic Acid, Polidocanol, 1064nm Nd:YAG laser, 755nm Alexandrite Laser
Drug · Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Sep 6, 2026, 10:13 AM EDT
Terminated Not applicable Interventional

Pulsed 1064nm Nd:YAG in the Treatment of Verruca Vulgaris Versus Conventional Therapy With Liquid Nitrogen Cryotherapy

NCT01609530
View directory record Official record
Conditions
Verruca Vulgaris
Interventions
Liquid Nitrogen Cryotherapy, Pulsed 1064nm Nd:YAG
Procedure
Lead sponsor
Trinity Health Michigan
Other
Eligibility
18 Years to 75 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Ypsilanti, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 21, 2018 · Synced Sep 6, 2026, 10:13 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Study of the Efficacy of 532nm Laser and 1064 nm Laser in the Treatment of Cutaneous Lupus Erythematous Versus Topical Corticosteroids Alone

NCT03639857
View directory record Official record
Conditions
Cutaneous Lupus
Interventions
532nm laser, 1064nm laser, Topical corticosteroid
Device · Drug
Lead sponsor
David Weinstein
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jul 20, 2021 · Synced Sep 6, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Pilot Study Testing 1064nm Q-switch Laser Versus Glycolic Acid Peels for the Treatment of Melasma

NCT01976273
View directory record Official record
Conditions
Melanosis
Interventions
1064nm Q-switch Laser, Glycolic Acid Peels
Device · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 5, 2021 · Synced Sep 6, 2026, 10:13 AM EDT
Recruiting Not applicable Interventional

Transcranial Photobiomodulation (tPBM) in Alzheimer's Disease Study

NCT07224607
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Photobiomodulation
Device
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
55 Years to 89 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Sep 6, 2026, 10:13 AM EDT