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ClinicalTrials.gov public records Last synced Nov 5, 2026, 7:19 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 217–240 of 1,230 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: 12 Week Exercise Intervention Clear all

Conditions: Stress, Stress, Psychological, Stress, Physiological, Stress, Emotional, Stress Reaction
Interventions: Education Program, Think Well Program, Be Well Program, Eat Well Program, Sleep Well Program, Move Well Program; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 712 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: GLP - 1, Obesity & Overweight, Muscle Loss, Exercise Intervention, Dietary Assessment
Interventions: Semaglutide, Dietary Counseling, Exercise; Drug · Behavioral
Lead sponsor: William Marsh Rice University; Other
Eligibility: 40 Years to 55 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Chronic Ankle Instability
Interventions: Neurocognitive Ankle Training for Instablity to Optimize Neuromusculoskeletal outcomes (NATION), Evidence-Based; Other
Lead sponsor: Womack Army Medical Center; Federal
Eligibility: 18 Years to 44 Years
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Lexington, Kentucky • Fort Bragg, North Carolina

Conditions: Smoking, Motivation, Smoking Cessation
Interventions: Nicotine Mini-Lozenge, Behavioral Reduction Counseling, 5Rs Motivation Counseling, Behavioral Activation Counseling, No Treatment; Drug · Behavioral · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 577 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Liver Cirrhoses, Portal Hypertension Related to Cirrhosis, Severe Obesity, TIPS
Interventions: Transjugular Intrahepatic Portosystemic Shunt (TIPS), Sleeve Gastrectomy, Anti-Obesity Pharmacotherapy (Class Effect), Lifestyle Counseling - Diet & Physical-Activity Program; Procedure · Drug · Behavioral
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 70 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2034
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Stroke
Interventions: Wellness in Rehabilitation program; Behavioral
Lead sponsor: VA Palo Alto Health Care System; Federal
Eligibility: 30 Years to 90 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Type 2 Diabetes Mellitus, Obesity
Interventions: Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention; Procedure · Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 25 Years to 55 Years
Enrollment: 69 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2028
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Sedentary Behavior, Behavior, Health, Cholesterolemia, Obesity, Stress, Hypertension, Fatigue, Glucose, High Blood, Mood
Interventions: Desk Only, Program Only; Device · Behavioral
Lead sponsor: Kansas State University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Manhattan, Kansas

Conditions: Peripheral Artery Disease, Exercise, Intermittent Claudication, Nitric Oxide
Interventions: Supervised Treadmill Exercise, Attention Control, Nitrate-Rich Beetroot Juice + supervised exercise therapy, Placebo + supervised exercise therapy; Behavioral · Combination Product
Lead sponsor: Northwestern University; Other
Eligibility: 50 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 2
States / cities: Chicago, Illinois

Conditions: Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Stage I Colorectal Cancer AJCC v8, Stage I Prostate Cancer AJCC v8, Stage II Colorectal Cancer AJCC v8, Stage II Prostate Cancer AJCC v8, Stage III Colorectal Cancer AJCC v8, Stage III Prostate Cancer AJCC v8
Interventions: Exercise Intervention, Informational Intervention, Nutritional Assessment, Physical Performance Testing, Quality-of-Life Assessment, Questionnaire Administration; Other
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 65 Years and older
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Osteoarthritis
Interventions: Exercise and Dietary Weight Loss, Walk with Ease; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 50 Years and older
Enrollment: 227 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Knee Osteoarthritis
Interventions: Remote Tai Chi; Other
Lead sponsor: Tufts Medical Center; Other
Eligibility: 50 Years to 100 Years
Enrollment: 480 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Ventral Hernia, Ventral Incisional Hernia, Post Operative Pain
Interventions: PT Group, Usual Care; Other
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2030
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Psychosocial Problem
Interventions: Health Education, Questionnaires, Telephone Counseling Sessions, Nicotine Patches; Behavioral · Drug
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 301 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2022
U.S. locations: 2
States / cities: Houston, Texas

Conditions: Colorectal Cancer
Interventions: Exercise Program, Telephone-based intervention, Counseling intervention, Questionnaire administration, Relaxation Program; Behavioral · Other
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 154 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2023
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Eating Disorders (Excluding Anorexia Nervosa), Binge-Eating Disorder
Interventions: Building Healthy Eating and Self-Esteem Together for University Students, Present-Centered Therapy; Behavioral
Lead sponsor: University of Kansas; Other
Eligibility: 18 Years to 65 Years
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Lawrence, Kansas

Conditions: Muscle Mass and Strength
Interventions: Resistance Exercise Program, Nutrition and Exercise Counseling; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older · Male only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Obesity and Type 2 Diabetes, Metabolic Diseases, High-intensity Interval Training, Time-restricted Eating
Interventions: High-intensity interval training, Time-restricted eating; Behavioral
Lead sponsor: Syracuse University; Other
Eligibility: 14 Years to 30 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Syracuse, New York

Conditions: Cardiovascular Diseases, Type 2 Diabetes Mellitus in Obese, Hyperlipidemias
Interventions: CHAI dyad study; Behavioral
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 20 Years to 70 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Mobility Limitation
Interventions: On the Move group exercise; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 60 Years and older
Enrollment: 529 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Vocal Cord Dysfunction
Interventions: Four therapy sessions with a psychologist utilizing cognitive-behavioral therapy techniques, Cognitive Behavioral Therapy (CBT); Behavioral
Lead sponsor: CAMC Health System; Other
Eligibility: 13 Years to 18 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Charleston, West Virginia

Conditions: Hypertension
Interventions: Eplerenone, Amlodipine, Microneurography, Rhythmic handgrip exercise, Sustained hand grip, Forearm blood flow, Arm cycling exercise, Cold Pressor test; Drug · Procedure
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2021
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Cardiovascular (CV) Risk
Interventions: Lion Hearts Family-Based Physical Activity Program; Behavioral
Lead sponsor: Penn State University; Other
Eligibility: 10 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: State College, Pennsylvania

Conditions: Obesity, Hyperlipidemia, Hypertension, Pre-diabetes, Diabetes
Interventions: Lifestyle Intervention, Print Health Education; Behavioral · Other
Lead sponsor: Northwestern University; Other
Eligibility: 30 Years to 60 Years
Enrollment: 63 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2015
U.S. locations: 2
States / cities: Chicago, Illinois

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Stress & Resilience Study

Combatting Muscle Loss in Obese Adult Patients on GLP-1 Medications Through Dietary Counseling and Exercise During Treatment Evaluates Whether a 12-week Exercise and Individualized Nutrition Program Can Reduce Muscle and Bone Loss and Improve Strength, Fitness, and Function in Obese Adults on GLP-1

Neurocognitive Ankle Training for Instability to Optimize Neuromusculoskeletal Outcomes (NATION)

Motivation Project: Testing Intervention Components for the Smoker Who is Unwilling to Quit

Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease

Effect of Lifestyle Changes on BDNF Level After Stroke

The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes

Stand Up Kansas: An Intervention to Reduce Sedentary Behavior in the Home Work Environment

Response to Exercise and Nitric Oxide in PAD

Online Dietary and Resistance Training to Improve Physical Function in Older Cancer Survivors, E-PROOF Trial

Collaborative Lifestyle Intervention Program in Knee Osteoarthritis Patients

Remote Tai Chi for Knee Osteoarthritis

The IMPACT Study: Personalized Physical Therapy for Better Recovery and a Stronger Core After Hernia Surgery

Reducing Cancer Disparities Among Latinos in Texas

Doctor-Recommended Home-Based Exercise Program or Relaxation Training in Improving Physical Function and Controlling Symptoms in Patients With Stage IV or Recurrent Colon Cancer That Cannot Be Removed By Surgery

Building Healthy Eating and Self-Esteem Together for University Students

Effects of Resistance Exercise Among TGD Individuals Initiating Estrogen-Based Gender-Affirming Hormone Therapy

Effects of HIIT vs. TRE on Type 2 Diabetes Risk

Implementation of a Peer Leader-facilitated Dyadic Intervention

Effectiveness of the On the Move Group Exercise Program to Improve Mobility in Community-dwelling Older Adults

A Multidisciplinary Approach to Vocal Cord Dysfunction: A Novel Pilot Study

The Role of Aldosterone on Augmented Exercise Pressor Reflex in Hypertension

Lions Hearts: A Community Approach to Multigenerational Cardiovascular Disease Risk

Translating a Heart Disease Lifestyle Intervention Into the Community