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Showing 1–24 of 100 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: 12 month behavioral weight loss intervention Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Optimal Timing of Exercise Initiation Within a Lifestyle Weight Loss Program

NCT01985568
View directory record Official record
Conditions
Obesity
Interventions
Sequential BT, Standard BT
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 55 Years
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Sep 28, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Examining Cooking as a Health Behavior

NCT03783962
View directory record Official record
Conditions
Obesity
Interventions
Active Intervention - Cooking, Demonstrations - Cooking
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated May 16, 2021 · Synced Sep 28, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Gender and Culturally Specific Approach to Reduce NAFLD in Mexican-American Men

NCT04186260
View directory record Official record
Conditions
NAFLD
Interventions
NAFLD-specific weight loss intervention, Wait-list control
Behavioral · Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 64 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 23, 2025 · Synced Sep 28, 2026, 2:13 AM EDT
Completed Not applicable Interventional

EMPOWER Men to Reduce Weight and Inhibit Prostate Cancer Progression

NCT04266431
View directory record Official record
Conditions
Prostatic Neoplasm
Interventions
EMPOWER
Behavioral
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 11, 2025 · Synced Sep 28, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Health-Smart for Weight Loss at UF Jax Clinics

NCT03418701
View directory record Official record
Conditions
Obesity
Interventions
Health Smart for Weight Loss
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 100 Years · Female only
Enrollment
683 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Sep 28, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sustainability of MOVE UP Lifestyle Intervention

NCT03963830
View directory record Official record
Conditions
Body Weight, Diet, Healthy, Physical Disability
Interventions
MOVE UP
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
60 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 1, 2021 · Synced Sep 28, 2026, 2:13 AM EDT
Completed Not applicable Interventional Results available

The GEM (Goals for Eating and Moving) Study

NCT03006328
View directory record Official record
Conditions
Weight Gain, Obesity
Interventions
GEM, Enhanced Usual Care
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 69 Years
Enrollment
489 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Sep 28, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Weight Tracking and Weight Loss Outcomes: Establishing the Standard of Care

NCT01646086
View directory record Official record
Conditions
Weight Loss
Interventions
12 month behavioral weight loss intervention
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 64 Years
Enrollment
339 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Sep 28, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Delicious Eating for Life in Southern Homes

NCT04302727
View directory record Official record
Conditions
Weight Loss, Diet, Healthy, Cardiovascular Risk Factor
Interventions
Med-South Weight Loss Intervention, WW
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 75 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Sep 28, 2026, 2:13 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Vivamos Activos Fair Oaks Program for Weight Loss in Low Income Latinos

NCT01242683
View directory record Official record
Conditions
Obesity
Interventions
Vivamos Activos Fair Oaks Program
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
207 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
4
States / cities
Palo Alto, California • Redwood City, California • San Mateo, California + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2014 · Synced Sep 28, 2026, 2:13 AM EDT
Completed Phase 2 Interventional Results available

Survivorship Promotion In Reducing IGF-1 Trial

NCT02431676
View directory record Official record
Conditions
Breast Cancer, Prostate Cancer, Lung Cancer, Colon Cancer, Melanoma of Skin, Endometrial Cancer, Liver Cancer, Pancreatic Cancer, Rectal Cancer, Kidney Cancer, Other Solid Malignant Tumors
Interventions
Metformin, Coach Directed Behavioral Weight Loss, Self-control weight loss
Drug · Behavioral
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Sep 28, 2026, 2:13 AM EDT
Completed Phase 2 Interventional Results available

Adaptive Nutrition and Exercise Weight Loss (A-NEW) Study

NCT04499950
View directory record Official record
Conditions
Breast Cancer, Overweight or Obesity
Interventions
Contrave, Behavioral Weight Loss
Drug · Behavioral
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older · Female only
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Sep 28, 2026, 2:13 AM EDT
Not yet recruiting Not applicable Interventional

Addressing Food Access and Physical Activity to Improve Diabetes Prevention Outcomes Among Underserved African Americans

NCT07560969
View directory record Official record
Conditions
Diabetes, Physical Activity, Food Security, Nutrition Security
Interventions
Culturally-tailored, enhanced adaption of Diabetes Prevention Program
Behavioral
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
18 Years and older
Enrollment
408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 28, 2026, 2:13 AM EDT
Completed Not applicable Interventional

Lifestyle, Exercise and Nutrition Study 2 (LEAN 2)

NCT02110641
View directory record Official record
Conditions
Breast Cancer, Weight Loss
Interventions
Weight Loss Counseling
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 20, 2023 · Synced Sep 28, 2026, 2:13 AM EDT
Recruiting Phase 4 Interventional

Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease

NCT07058155
View directory record Official record
Conditions
Liver Cirrhoses, Portal Hypertension Related to Cirrhosis, Severe Obesity, TIPS
Interventions
Transjugular Intrahepatic Portosystemic Shunt (TIPS), Sleeve Gastrectomy, Anti-Obesity Pharmacotherapy (Class Effect), Lifestyle Counseling - Diet & Physical-Activity Program
Procedure · Drug · Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2034
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Sep 28, 2026, 2:13 AM EDT
Completed Not applicable Interventional

Faith-based Approaches in the Treatment of Hypertension (FAITH)

NCT01065831
View directory record Official record
Conditions
Hypertension
Interventions
Motivational interviewing (MINT-TLC)
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
373 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 29, 2016 · Synced Sep 28, 2026, 2:13 AM EDT
Not listed No phase listed Observational

Evaluation of a Telehealth DPP With Medicare Patients at the University of Mississippi Medical Center

NCT04822480
View directory record Official record
Conditions
PreDiabetes, Prediabetic State
Interventions
Diabetes Prevention Program (DPP)
Behavioral
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Apr 28, 2024 · Synced Sep 28, 2026, 2:13 AM EDT
Completed Not applicable Interventional

Diabetes Prevention for Mexican Americans

NCT03208010
View directory record Official record
Conditions
Prediabetic State, Overweight and Obesity
Interventions
Diabetes Prevention Intervention, Enhanced Usual Care
Behavioral · Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
25 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Rio Grande City, Texas
Source: ClinicalTrials.gov public record
Updated Oct 16, 2023 · Synced Sep 28, 2026, 2:13 AM EDT
Completed Not applicable Interventional

Exercise Training After an Acute Blood Clot

NCT01864447
View directory record Official record
Conditions
VTE
Interventions
VTE REHABILITATION: High-Caloric Expenditure Exercise Training (HCE) and The Dietary Behavioral Weight Loss Intervention (BWL)
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
16 Years to 79 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Dec 3, 2014 · Synced Sep 28, 2026, 2:13 AM EDT
Completed Not applicable Interventional Results available

Research Intervention to Support Healthy Eating and Exercise

NCT04353258
View directory record Official record
Conditions
Obesity
Interventions
Behavioral Economics intervention (BE mHealth), Standard mHealth intervention (mHealth)
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 75 Years
Enrollment
195 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Sep 28, 2026, 2:13 AM EDT
Terminated Not applicable Interventional

Sustaining the Reach of a Scalable Weight Loss Intervention Through Financial Incentives

NCT04225234
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Financial incentives
Other
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 4, 2024 · Synced Sep 28, 2026, 2:13 AM EDT
Completed Not applicable Interventional

State-wide Health Approach to Increase Reach and Effectiveness: Study 3

NCT01760486
View directory record Official record
Conditions
Obesity
Interventions
Shape Up Rhode Island, Shape Up Rhode Island + Professional Coach + Incentives, Shape Up Rhode Island + Peer Coach + Incentives
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 11, 2016 · Synced Sep 28, 2026, 2:13 AM EDT
Recruiting Not applicable Interventional

Redefining BMI: The Body, Mind, and Inflammation Trial

NCT06532747
View directory record Official record
Conditions
Obesity, Adiposity
Interventions
Integrated Lifestyle Intervention (ILI), Monitoring with digital tools
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 25 Years · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 28, 2026, 2:13 AM EDT
Active, not recruiting Phase 4 Interventional

Long-term Effectiveness of the Antiobesity Medication Phentermine

NCT05176626
View directory record Official record
Conditions
Obesity, Obesity; Drug, Lifestyle, Healthy
Interventions
Online Lifestyle Behavioral Therapy, Phentermine Hydrochloride 8 MG
Behavioral · Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 70 Years
Enrollment
870 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
4
States / cities
Los Angeles, California • Saint Louis Park, Minnesota • Winston-Salem, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 28, 2026, 2:13 AM EDT