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ClinicalTrials.gov public records Last synced Nov 15, 2026, 4:40 AM EST

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Showing 1–24 of 29 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: 12-step facilitation Clear all

Conditions: Alcohol Abuse, Drug Abuse
Interventions: Multimedia 12-Step Toolkit, Treatment as Usual; Behavioral
Lead sponsor: Treatment Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 3,483 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 11
States / cities: Camden, New Jersey • Brooklyn, New York • Eagleville, Pennsylvania + 2 more

Conditions: Substance-Related Disorders, Drug Addiction, Substance Abuse
Interventions: Community Reinforcement and Family Training, Al-Anon Facilitation; Behavioral
Lead sponsor: Treatment Research Institute; Other
Eligibility: 12 Years and older
Enrollment: 126 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Drug Abuse
Interventions: STAGE-12, Treatment as Usual; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 471 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 10
States / cities: Jacksonville, Florida • Kaneohe, Hawaii • Columbus, Ohio + 7 more

Conditions: Cognitive Change
Interventions: C1 - Standard Perceptual Learning (SPL), C2 - Long Training (LT), C3 - Short Staircases (SS), C4 - Mixed Difficulty (MD), C5 - Noise Training (NT), C6 - Training with Flankers (TWF), C7 - Parafoveal Training (PT), C8 - Stimulus Variety (SV), C8a - Complex Features (CF), C9 - Exogenous Attention Training (ExAT), C10 - Endogenous Attention Training (EnAT), C11 - Multisensory Facilitation (MF), No Contact Control; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 85 Years
Enrollment: 1,140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 3
States / cities: Riverside, California • Boston, Massachusetts • Madison, Wisconsin

Conditions: Drug Addiction, Stimulant Dependence, Opiate Dependence, Alcohol Dependence, Substance Abuse
Interventions: Community Reinforcement and Family Training, Treatment Entry Training, 12- step Al/Nar- Anon Facilitation; Behavioral
Lead sponsor: Treatment Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Depression, Anxiety
Interventions: Stage 1 Strategy: REP, Stage 1 Strategy: REP + Coaching, Stage 2 Strategy: Augment with Facilitation, Stage 2 Strategy: No augmentation; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 14 Years to 99 Years
Enrollment: 1,329 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Opioid-use Disorder, Stress Related Disorder, Anxiety, Pain Interference
Interventions: Live-Online M-ROCC, Live-Online Control; Behavioral
Lead sponsor: Cambridge Health Alliance; Other
Eligibility: 18 Years to 70 Years
Enrollment: 260 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Somerville, Massachusetts

Conditions: Alcohol Abuse, Alcohol Dependence, Drug Abuse, Drug Dependence
Interventions: Integrated Twelve-Step Facilitation, Cognitive Behavioral Therapy; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 14 Years to 21 Years
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Substance Abuse, Depression, Anxiety Disorder
Interventions: Mindfulness Based Relapse Prevention (MBRP), Twelve-Step Facilitation Intervention (TSF); Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 75 Years
Enrollment: 204 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 2
States / cities: Tuscaloosa, Alabama • Charleston, South Carolina

Conditions: Cocaine Dependence
Interventions: Behavioral therapy; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 145 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1994 – 2002
U.S. locations: 2
States / cities: New Haven, Connecticut

Conditions: Alcoholism, Diagnosis, Dual (Psychiatry)
Interventions: 12-step facilitation, Treatment as usual; Behavioral
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older
Enrollment: 121 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2011
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Anxiety, Depression, Post Traumatic Stress Disorder, Satisfaction
Interventions: POST Facilitation, Home Safety Evaluation; Behavioral
Lead sponsor: Indiana University; Other
Eligibility: 65 Years and older
Enrollment: 389 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 3
States / cities: Indianapolis, Indiana

Conditions: Substance-Related Disorders, Depressive Disorder
Interventions: Twelve Step Facilitation, Integrated Cognitive Behavioral Treatment; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 276 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2000 – 2012
U.S. locations: 1
States / cities: San Diego, California

Conditions: Alcohol Abuse, Alcohol Dependence
Interventions: Motivation Enhancement Therapy (MET), Peer-Twelve Step Facilitation (P-TSF); Behavioral
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Alcohol Dependence, Dual Diagnosis, Drug Dependence
Interventions: Arm 1 GMI, Arm 2 IHMD, Arm 3 TCC; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 70 Years
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Substance Abuse, HIV Infections
Interventions: contingency management; Behavioral
Lead sponsor: UConn Health; Other
Eligibility: 18 Years to 65 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Hartford, Connecticut

Conditions: Addiction
Interventions: Mobile Continuing Care; Behavioral
Lead sponsor: Azusa Pacific University; Other
Eligibility: 12 Years to 24 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Azusa, California

Conditions: Opiate Use Disorder
Interventions: Addiction Pilot App behavior tracking; Behavioral
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Warrensville Heights, Ohio

Conditions: Substance Use Disorders
Interventions: A Woman's Path to Recovery, 12-Step Facilitation; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 2
States / cities: Bedford, Massachusetts • Boston, Massachusetts

Conditions: Alcohol Withdrawal
Interventions: Prazosin, 12-Step Facilitation with Relapse Prevention and Contingency Management; Drug · Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 152 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Stress Disorders, Post-Traumatic, Substance-Related Disorders
Interventions: Cognitive Behavioral Therapy, Individual Addiction Counseling, Treatment-as-usual; Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 443 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 4
States / cities: Berlin Corners, Vermont • Brattleboro, Vermont • Burlington, Vermont + 1 more

Conditions: Alcohol Dependence, Drug Dependence
Interventions: Making Alcoholics Anonymous Easier (MAAEZ), Usual care; Behavioral
Lead sponsor: Alcohol Research Group; Other
Eligibility: 18 Years and older
Enrollment: 508 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Emeryville, California

Conditions: Substance Use Disorders, Family Members
Interventions: CRAFT-AI, TSF-CSO; Behavioral
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Zuni, New Mexico

Conditions: Cancer of Liver, Cancer of Colon, Cirrhosis
Interventions: Patient Navigation, Implementation Facilitation; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 30,300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2030
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Search by objective public record fields.

Multimedia Toolkits to Implement 12-Step Recovery Concepts in Group Counseling

Family Training Program for Parents of Substance Using Adolescents

Stimulant Abuser Groups to Engage in 12-Step

Moderators and Mediators of Perceptual Learning

CRAFT Behavior Therapy: Treatment Entry Component

Improving Student Mental Health: Adaptive School-based Implementation of CBT

Effect of Mindfulness on Opioid Use and Anxiety During Primary Care Buprenorphine Treatment (R33 Phase)

Development and Testing of Adolescent Twelve-Step Facilitation

Mindfulness-Based Recovery in Veterans

Behavioral Treatment for Cocaine Dependent Women

12-step Facilitation for the Dually Diagnosed

POST Facilitation for Community Dwelling Older Adults (POST-RCT)

Integrated Intervention for Substance Abusers With Depressive Disorders

Facilitating Aftercare for Alcohol Detox Patients

Impact of Group Motivational Interviewing and In-Home-Messaging-Devices for Dually Diagnosed Veterans

Healthy Activities for Prize Incentives

Mobile Continuing Care Approach for Youth

Application Based Addiction Treatment Adherence Trial

Women Veterans' Substance Abuse Treatment

Prazosin for Alcohol Use Disorder With Withdrawal Symptoms

Cognitive Behavioral Therapy (CBT) for Posttraumatic Stress Disorder (PTSD) in Community Addiction Treatment

Making Alcoholics Anonymous Easier

Testing Effectiveness of the Community Reinforcement Approach and Family Training (CRAFT) With American Indians

Getting To Implementation: Improving Cancer Screening for Veterans