Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:53 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 217–240 of 272 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: 12-weeks of Weight Loss Clear all

Conditions: Obesity
Interventions: EndoFLIP device (FDA Device Listing Number : D091203); Device
Lead sponsor: Crospon; Industry
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Hurst, Texas

Conditions: Obesity
Interventions: Mindfulness Based Weight Loss Maintenance (MBWLM), Behavioral: Standard Behavioral Weight-Loss Maintenence; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 95 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2010
U.S. locations: 2
States / cities: Durham, North Carolina • Philadelphia, Pennsylvania

Conditions: High Blood Pressure
Interventions: Yoga exercise program, Blood pressure education/walking program; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 75 Years
Enrollment: 147 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Obesity
Interventions: Behavioral Treatment, Placebo, Semaglutide 2.4 MG/0.75 ML Subcutaneous Solution [WEGOVY]; Behavioral · Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 70 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Stage I Endometrial Adenocarcinoma, Uterine Cancer, Obesity
Interventions: Exercise on stationary recumbent exercise cycle, Health Education, Questionnaires, Neuroimaging, Genetic and Biomarkers; Behavioral · Procedure
Lead sponsor: Case Comprehensive Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2019
U.S. locations: 2
States / cities: Cleveland, Ohio

Conditions: Prostatic Neoplasm
Interventions: EMPOWER; Behavioral
Lead sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; Other
Eligibility: 18 Years and older · Male only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Colon Cancer, Obesity
Interventions: High Fiber Diet Featuring Legumes (HLD), Healthy American Diet; Dietary Supplement
Lead sponsor: Emory University; Other
Eligibility: 40 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Obesity, Overweight
Interventions: Whole Food Plant-Based Behavioral Weight Loss Treatment; Behavioral
Lead sponsor: Drexel University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Obesity
Interventions: CP-741,952; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2007
U.S. locations: 5
States / cities: Ann Arbor, Michigan • Kalamazoo, Michigan • New York, New York + 2 more

Conditions: Cachexia, Weight Loss, Gastrointestinal Cancer
Interventions: EXCAP©®; Other
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Gestational Diabetes
Interventions: Prevention of recurrent gestational diabetes through weight loss and exercise (English & Spanish), Lifestyle education (English & Spanish); Behavioral
Lead sponsor: California Polytechnic State University-San Luis Obispo; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: San Luis Obispo, California

Conditions: Overweight and Obesity, Weight Loss
Interventions: Time restricted feeding, Normal feeding; Other
Lead sponsor: Kyle Hackney; Other
Eligibility: 35 Years to 60 Years
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Fargo, North Dakota

Conditions: Obesity
Interventions: Escalating Lottery; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 30 Years to 80 Years
Enrollment: 259 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Type 2 Diabetes, PreDiabetes
Interventions: NDPP + Basketball (BB), NDPP Standard of Care SOC; Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years to 44 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Overweight and/or Obesity
Interventions: AGILE Intervention, Chatbot; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 39 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Overweight, Obesity
Interventions: SisterTalk Hartford, Attention control video series; Behavioral
Lead sponsor: UConn Health; Other
Eligibility: 18 Years and older · Female only
Enrollment: 322 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2006
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Unspecified Adult Solid Tumor, Protocol Specific, Weight Changes
Interventions: Megestrol Acetate, Oxandrolone 20 mg; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 155 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 20
States / cities: Newark, Delaware • Miami Beach, Florida • Louisville, Kentucky + 16 more

Conditions: Stress, Weight
Interventions: Comprehensive Dietary Self-Monitoring; Device: smartphone; Other: physical activity, Simple Dietary Self-Monitoring; Device: smartphone; Other: physical activity; Behavioral
Lead sponsor: University of Connecticut; Other
Eligibility: 18 Years to 65 Years
Enrollment: 64 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Storrs, Connecticut

Conditions: Time Restricted Feeding
Interventions: 14:10 Regimen, 12:12 Regimen; Behavioral
Lead sponsor: Jenny Craig, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 113 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Carlsbad, California

Conditions: Overweight/Obesity
Interventions: Snack Type 1: Walnuts, Snack Type 2: Pretzels; Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 25 Years to 45 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Obesity, Overweight, Binge Eating
Interventions: Interpersonal Psychotherapy, Health Education; Behavioral · Other
Lead sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine; Other
Eligibility: 12 Years to 17 Years
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2021
U.S. locations: 2
States / cities: Bethesda, Maryland • Fort Belvoir, Virginia

Conditions: Advanced Malignant Solid Neoplasm, Advanced Biliary Tract Carcinoma, Advanced Esophageal Carcinoma, Metastatic Esophageal Carcinoma, Locally Advanced Colorectal Carcinoma, Locally Advanced Esophageal Carcinoma, Locally Advanced Gastric Carcinoma, Metastatic Colorectal Carcinoma (mCRC), Advanced Lung Carcinoma, Locally Advanced Hepatocellular Carcinoma
Interventions: Olanzapine, Placebo Administration, Questionnaire Administration; Drug · Other
Lead sponsor: OHSU Knight Cancer Institute; Other
Eligibility: 18 Years and older
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Osteoarthritis, Knee, Osteoarthritis, Hip, Overweight, Obesity, Physical Inactivity, Weight Loss
Interventions: OA CARE Intervention, Usual Care control group; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 99 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Breast Cancer
Interventions: Cognitive behavioral therapy CBT) for weight loss; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 90 Years · Female only
Enrollment: 253 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: La Jolla, California

Search by objective public record fields.

LapBand Adjustment to Improve Early Weight Loss

Engaging Motivation for the Prevention of Weight Regain

Lifestyle Modification and Blood Pressure Study

Semaglutide Treatment, Appetite, and Eating Behavior: Long-term Effects

Assisted Exercise in Obese Endometrial Cancer Patients

EMPOWER Men to Reduce Weight and Inhibit Prostate Cancer Progression

Fiber-rich Foods to Treat Obesity and Prevent Colon Cancer

Evaluating a Remotely Delivered Plant-Based Behavioral Weight Loss Treatment

Safety, Toleration and Efficacy of CP-741,952 for the Treatment of Obesity

The Effects of a 12 Week Home-based Exercise Intervention on Physical Performance in Patients With Cancers of the Gastrointestinal Tract With Pre- Cachexia or Cachexia

A Pilot Study Using Weightloss and Exercise to Prevent Recurring Gestational Diabetes in Obese Women

Exercise Training and Time-restricted Feeding in Overweight and Obese Adults

The Weigh Forward, Financial Incentives for Maintenance of Weight Loss

Recreational Basketball to Increase Participation in Diabetes Prevention

Piloting a Generative Artificial Intelligence Chatbot in a Mobile Weight Loss Program

Effectiveness of SisterTalk Hartford for Weight Loss Among African-American Women

Oxandrolone Compared With Megestrol in Preventing Weight Loss in Patients Receiving Chemotherapy for Cancer

RELAX: A Mobile Application Suite Targeting Obesity and Stress

Effect of 14:10 Time-Restricted Eating on Body Weight and Metabolic Markers

Snacking Effects on the Brain Response to Foods and Satiety During Dieting

Preventing Obesity in Military Communities-Adolescents

Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer

OA Clinic-Community CARE Model

Weight Reduction Intervention for Breast Cancer Survivors