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ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:05 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 241–264 of 272 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: 12-weeks of Weight Loss Clear all

Conditions: Metabolic Syndrome X, Prediabetic State, Insulin Resistance, Obesity, Metabolic Diseases
Interventions: Dietary supplement for weight loss, Education and counseling for weight loss; Drug · Behavioral
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 21 Years to 60 Years
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2014
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Binge Eating/Loss of Control Eating
Interventions: Linking Individuals Being Emotionally Real (LIBER8), Weight Management Control; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 13 Years to 22 Years · Female only
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Diabete Type 2, Diabetes, Overweight , Obesity
Interventions: Intensive Multicomponent Healthy Eating and Weight Loss Intervention, Enhanced Usual Diabetes Care; Behavioral
Lead sponsor: University of Tennessee; Other
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 2
States / cities: Memphis, Tennessee

Conditions: Overweight and Obesity
Interventions: Experimental: Lifestyle Intervention with Body Image Treatment (LIBI), Lifestyle Intervention (LI); Behavioral
Lead sponsor: Texas Tech University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 2
States / cities: Lubbock, Texas

Conditions: Obesity
Interventions: Food Response Training (FRT); Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 80 Years
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 2
States / cities: New York, New York

Conditions: Weight Loss
Interventions: Ideal Protein Weight Loss Method, Standard Weight Loss; Behavioral
Lead sponsor: Tulane University; Other
Eligibility: 22 Years to 79 Years
Enrollment: 192 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Bogalusa, Louisiana

Conditions: Osteoarthritis
Interventions: Exercise and Dietary Weight Loss, Walk with Ease; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 50 Years and older
Enrollment: 227 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Obesity
Interventions: Internet Only, Internet + Incentives; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older
Enrollment: 418 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 2
States / cities: Columbia, South Carolina • Burlington, Vermont

Conditions: Overweight, Obesity
Interventions: Weight loss; Behavioral
Lead sponsor: University of North Carolina, Greensboro; Other
Eligibility: 18 Years and older · Female only
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Greensboro, North Carolina

Conditions: Cachexia, Non-Small-Cell Lung Cancer, Pancreatic Cancer, Colorectal Cancer
Interventions: PF-06946860; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 10
States / cities: Beverly Hills, California • Grand Junction, Colorado • Wheat Ridge, Colorado + 7 more

Conditions: Obesity
Interventions: Liquid meal responses, fMRI responses to food-cues; Procedure · Behavioral
Lead sponsor: New York Obesity and Nutrition Research Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: New York, New York

Conditions: Obesity
Interventions: Internet-based weight loss program, Yoga, Health and Wellness; Behavioral
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 210 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Weight Loss
Interventions: Transform Burn; Dietary Supplement
Lead sponsor: 4Life Research, LLC; Industry
Eligibility: 18 Years to 72 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 1
States / cities: Sandy City, Utah

Conditions: Obesity
Interventions: APD356; Drug
Lead sponsor: Eisai Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 400 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Arthroplasties, Replacement, Weight Loss, Nutrition
Interventions: Remote dietitian supervised weight loss intervention and mobile app; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 3
States / cities: Boston, Massachusetts

Conditions: Bariatric Surgery, Weight Loss
Interventions: Guided Self-Help Behavioral Weight Loss; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Obesity, Weight Loss
Interventions: Weight loss group (Full meal replacement products); Dietary Supplement
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 50 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Obesity
Interventions: Dietary; Other
Lead sponsor: Banner Health; Other
Eligibility: 18 Years to 50 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 2
States / cities: Gilbert, Arizona • Phoenix, Arizona

Conditions: PreDiabetes, Prediabetic State
Interventions: Diabetes Prevention Program (DPP); Behavioral
Lead sponsor: University of Mississippi Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Jackson, Mississippi

Conditions: Obesity
Interventions: GW869682; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 64 Years
Enrollment: 136 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006
U.S. locations: 3
States / cities: Daytona Beach, Florida • Baton Rouge, Louisiana • Portland, Oregon

Conditions: Breast Cancer, Obesity, Weight Changes
Interventions: behavioral dietary intervention, Exercise intervention; Behavioral
Lead sponsor: Fred Hutchinson Cancer Center; Other
Eligibility: 50 Years to 75 Years · Female only
Enrollment: 439 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2010
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Overweight
Interventions: High protein, high fiber dietary supplement, Placebo; Dietary Supplement
Lead sponsor: Beachbody; Industry
Eligibility: 25 Years to 50 Years
Enrollment: 206 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Obesity
Interventions: Go! Foods for You without Weekly MA Support., Go! Foods for You with Weekly MA Support.; Behavioral
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 70 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Overweight
Interventions: Weight Maintenance, Weight Maintenance + Intermittent Fasting; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 50 Years to 75 Years
Enrollment: 175 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 2
States / cities: Baltimore, Maryland • San Antonio, Texas

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Education, Counseling, and Drug Therapy to Reduce Symptoms of Metabolic Syndrome

An Integrative Intervention for Loss of Control Eating Among Adolescent Girls

The Healthy Eating and Active Living to Reverse Diabetes Pilot Study

Optimizing Weight Loss Outcomes Through Body Image Enhancement

The Retrain Your Brain for Healthy Eating Study

A Trial of the Ideal Protein System Versus Low Fat Diet for Weight Loss

Collaborative Lifestyle Intervention Program in Knee Osteoarthritis Patients

Internet Assisted Obesity Treatment Enhanced With Financial Incentives

Get Active and Eat Right: Moms at Work

Study to Assess the Safety and Tolerability of Repeated Doses of an Investigational New Drug in Patients With Cancer and Cachexia.

fMRI and Appetite-Related Hormones Pre and Post Obesity Surgery

Strategies for Improving Remote-based Weight Loss (PATH Trial)

Effect of Transform Burn on Weight Loss

Safety and Efficacy of APD356 in the Treatment of Obesity

Weight Loss Before Total Joint Arthroplasty Using A Remote Dietitian and Mobile App

Bariatric Scalable Internet Treatments

Weight Loss Study-Mechanism Underlying the Improvement of Insulin Resistance in Response to Weight Loss

Validation of a Personal Breath Analyzer for Diet and Energy Expenditure Assessment and Management

Evaluation of a Telehealth DPP With Medicare Patients at the University of Mississippi Medical Center

Weight Loss In Obese Subjects Taking Either GW869682 Or Placebo 3 Times Per Day For 12 Weeks

Effect of a Low-Calorie Diet and/or Exercise Program on Risk Factors for Developing Breast Cancer in Overweight or Obese Postmenopausal Women

The Effect of a High Protein, High Fiber Dietary Supplement on Weight and Fat Loss

Effectiveness of an Eight Week Online Mediterranean Based Diet

Promotion of Weight Management