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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:38 AM EST

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Showing 97–120 of 272 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: 12-weeks of Weight Loss Clear all

Conditions: Health Behavior
Interventions: Counseling, feedback report; Behavioral
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Overweight, Type 2 Diabetes Mellitus, Type 1 Diabetes Mellitus
Interventions: Lifestyle Intervention, No Intervention; Other
Lead sponsor: Joslin Diabetes Center; Other
Eligibility: 18 Years to 65 Years · Male only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Weight Loss
Interventions: Weekly Incentive; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 70 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Heart Failure, Diabetes Mellitus
Interventions: 12-week supervised weight loss intervention; Procedure
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 1
States / cities: Orange, California

Conditions: Weight Loss, Blood Pressure, Lipid Disorder, PreDiabetes, Diabete Mellitus
Interventions: Low-fat plant-based diet; Behavioral
Lead sponsor: Physicians Committee for Responsible Medicine; Other
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Obesity
Interventions: Shape Up Rhode Island + Online Resources, Shape Up Rhode Island + Online Weight Loss Program, Shape Up Rhode Island + Online Weight Loss Program + Group sessions; Behavioral
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years to 70 Years
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Prediabetes
Interventions: National Diabetes Prevention Program (DPP), Sleep Health Digital Application, Time-Restricted Eating (TRE); Behavioral
Lead sponsor: University of Delaware; Other
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Obesity
Interventions: Diet and Activity Education, Self-monitoring with Feedback; Behavioral
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years to 70 Years
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Obesity &Amp;Amp;Amp; Overweight, Environmental Exposure, Overweight (BMI > 25)
Interventions: Educational curriculum, Weight loss Application, Urinary EDC metabolite testing, Siphox clinic biomarker test, Weight loss reporting; Behavioral · Diagnostic Test
Lead sponsor: Million Marker Wellness, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 226 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Berkeley, California

Conditions: Obesity, Weight Loss, Weight, Body, Cardiometabolic Syndrome
Interventions: Exercise; Behavioral
Lead sponsor: Lindenwood University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Saint Charles, Missouri

Conditions: Obesity, Osteoarthritis
Interventions: Vest, Diet; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 65 Years to 79 Years
Enrollment: 37 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Obesity, Overweight
Interventions: Teaching Obesity Treatments to Adult Learners (TOTAL), Usual care; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 70 Years
Enrollment: 440 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: West Los Angeles, California • Madison, Wisconsin

Conditions: Obesity, Diabetes Mellitus, Type 2
Interventions: Meal replacement system, Intensive lifestyle Intervention; Dietary Supplement · Behavioral
Lead sponsor: Loma Linda University; Other
Eligibility: 25 Years to 65 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Diabetic Polyneuropathy, Weight Loss
Interventions: Weight Achievement and Intensive Treatment (Why WAIT); Other
Lead sponsor: Joslin Diabetes Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Obesity, Food Insecurity
Interventions: BWL+VOUCHER, BWL+HOME, Behavioral weight loss counseling (BWL); Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 105 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Obesity, PreDiabetes
Interventions: Liraglutide, Sitagliptin, hypocaloric diet, Placebos, Exendin (9-39); Drug · Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 329 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Obesity, Stroke
Interventions: Lifestyle Management Program, Post-stroke Optimization of Walking using Explosive Resistance; Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 35 Years to 85 Years
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Obesity
Interventions: Weight loss core, Weight loss core plus maintenance; Behavioral
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years and older
Enrollment: 425 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2018
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Weight Loss
Interventions: Behavioral weight loss program; Behavioral
Lead sponsor: East Carolina University; Other
Eligibility: 18 Years and older
Enrollment: 54 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Greenville, North Carolina

Conditions: Type 2 Diabetes
Interventions: Roux-en-Y Gastric Bypass surgery, Laparoscopic Adjustable Gastric Banding surgery, Intensive Lifestyle Modification; Procedure · Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 65 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Melanocortin Obesity Syndrome, MCOS
Interventions: Atomoxetine, Placebo; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 6 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 3
States / cities: New York, New York • Columbus, Ohio • Nashville, Tennessee

Conditions: Chronic Kidney Disease, Obesity
Interventions: Diet and exercise, Bariatric Surgery; Behavioral · Procedure
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 19 Years to 99 Years
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Obesity
Interventions: Behavioral weight loss followed by yoga instruction, Behavioral weight loss followed by cooking/dietary education instruction; Behavioral
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years to 60 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Overweight, Obesity
Interventions: internet, in-person and internet+in-person; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older
Enrollment: 481 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2009
U.S. locations: 2
States / cities: Little Rock, Arkansas • Burlington, Vermont

Search by objective public record fields.

Behavioral CVD Prevention Using Informatics

Impact of Metabolic Health on Sperm Epigenetic Marks in Humans

Helping Employees Lose Pounds

Effects of a High Protein Diet on Clinical Outcomes in Heart Failure

Feasibility & Implementation of a Plant-Based Weight-Loss Program in an Office-Based Setting

State-wide Health Approach to Increase Reach and Effectiveness: Study 1

Nested Pilot Study Comparing Two Treatments to Reduce Type 2 Diabetes Risk in At-Risk Delawareans

Innovative Technology To Improve Patient Adherence To Weight Loss Recommendations

Weight Loss and Endocrine Disrupting Chemicals (EDCs): Lifestyle Interventions to Lose Weight and Reduce EDC Exposure in Individuals With Overweight/Obesity

Effects of Adding L-BAIBA to Exercising Adult Overweight and Obese Men and Women

Arthritis Pilot for Preserving Muscle While Losing Weight

Teaching Obesity Treatment Options to Adult Learners (TOTAL): A Multisite RCT

Weight Management for the Remission of Type 2 Diabetes Using a Proprietary Meal Replacement System- Diabetes Remission Study (DRS)

Evaluating the Effect of Diabetes Control Through Intensive Lifestyle Modifications on Diabetic Peripheral Neuropathy

FoodRx for Obesity Treatment

Cardiovascular Effects of GLP-1 Receptor Activation

EMPOWER: Effects of Weight Loss and Exercise Post-stroke

Weight Loss and Maintenance for Rural, African American Communities of Faith (The WORD)

The Addition of Self-compassion Skills Training to a Behavioral Weight Loss Program Delivered Using Video Conferencing Software

Surgery Or Lifestyle Intervention for Type 2 Diabetes (SOLID)

Atomoxetine in Melanocortin Obesity Syndrome

Effects of Intentional Weight Loss Interventions in Chronic Kidney Disease

Approaches for Improving Long-term Weight Loss

Internet Assisted Obesity Treatment