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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:57 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 121–144 of 272 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: 12-weeks of Weight Loss Clear all

Conditions: Obesity, Overweight, Weight Loss, Health Behavior
Interventions: Core Behavioral Weight Loss Intervention, Easier Step Goal, Harder Step Goal, Easier Calorie Goal, Harder Calorie Goal, Easier Eating Window Goal, Harder Eating Window Goal, Easier Red Zone Food Goal, Harder Red Zone Food Goal; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Pediatric Obesity
Interventions: Topiramate, Phentermine; Drug
Lead sponsor: Janey Pratt; Other
Eligibility: 12 Years to 25 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Cancer Survivor, Colorectal Cancer, Weight Changes
Interventions: Internet weight loss intervention; Behavioral
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 21 Years to 120 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2017
U.S. locations: 2
States / cities: New Brunswick, New Jersey • Philadelphia, Pennsylvania

Conditions: Obesity
Interventions: Active Intervention - Cooking, Demonstrations - Cooking; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older
Enrollment: 56 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Stress Reaction, Sleep Disturbance, Craving, Obesity
Interventions: Ashwagandha Root Extract Capsule, Placebo Capsule; Dietary Supplement · Other
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea, Overweight and Obesity
Interventions: FOCuSEd Integrated Intervention, Enhanced Usual Care; Other
Lead sponsor: Seattle Institute for Biomedical and Clinical Research; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 5
States / cities: Boise, Idaho • Chicago, Illinois • Minneapolis, Minnesota + 2 more

Conditions: Obesity
Interventions: GF-IGB: Obalon Balloon, Medically Supervised Meal Replacement Program: My New Weigh, Endoscopic sleeve gastroplasty: (ESG); Device · Dietary Supplement · Procedure
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 22 Years to 65 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Metabolism and Nutrition Disorder, Obesity
Interventions: liraglutide, placebo; Drug
Lead sponsor: Novo Nordisk A/S; Industry
Eligibility: 18 Years and older
Enrollment: 422 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 27
States / cities: Goodyear, Arizona • Peoria, Arizona • Huntington Beach, California + 22 more

Conditions: Obesity, Overweight
Interventions: Internet-based maintenance program; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 330 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Obesity, Hypertension, Diabetes Mellitus, Type 2
Interventions: Overstitch Endoscopic Suture System, Lifestyle Intervention; Device · Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 21 Years to 65 Years
Enrollment: 208 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 9
States / cities: Orlando, Florida • Chicago, Illinois • Evanston, Illinois + 6 more

Conditions: Obesity, Overweight
Interventions: Behavioral Weight Loss (BWL), Early Responder: BWL continued, Early Non-responder: BWL continued with medication added; Behavioral · Combination Product
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Obesity
Interventions: Vida Sana, Vida Sana y Completa; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 412 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Redwood City, California

Conditions: Heart Failure, Malnutrition
Interventions: Medically-Tailored Meals (MTMs), Protein supplementation shakes; Other · Dietary Supplement
Lead sponsor: Tufts Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Adolescent Obesity, Obesity in Adolescence, Adolescent Overweight
Interventions: VI-0521 oral capsule, Placebo oral capsule, Lifestyle Modification; Drug · Behavioral
Lead sponsor: VIVUS LLC; Industry
Eligibility: 12 Years to 16 Years
Enrollment: 223 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Norman, Oklahoma

Conditions: Obesity and Overweight
Interventions: Diet, Aerobic Exercise, Behavioral Sessions, Aerobic + Yoga Exercise; Behavioral
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 290 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Overweight, Obesity, Weight Loss
Interventions: Colorado Diet with soy protein foods., Colorado Diet with monetary payments; Dietary Supplement · Behavioral
Lead sponsor: DuPont Nutrition and Health; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Obese Adults
Interventions: VK2735 Drug, Placebo; Drug
Lead sponsor: Viking Therapeutics, Inc.; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Lake Forest, California • Miami, Florida

Conditions: Obesity
Interventions: Inpatient weight loss counseling, Motivational interviewing and troubleshooting via phone; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 176 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: ARTHROPLASTY, REPLACEMENT
Interventions: PACE, Delayed PACE; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 40 Years to 79 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Physical Inactivity, Overweight and Obesity
Interventions: Prevent T2, Move group-based classes, Fitness Membership, Mental Imagery, Move 1:1 Support; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 65 Years
Enrollment: 64 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Knoxville, Tennessee

Conditions: Weight Loss
Interventions: Get Social, Traditional, Smartphone; Behavioral · Device
Lead sponsor: University of Connecticut; Other
Eligibility: 18 Years to 65 Years
Enrollment: 329 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Storrs, Connecticut

Conditions: Overweight and Obesity, Pediatric Obesity, Eating, Binge
Interventions: Pathways to Health, Be4U; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 13 Years to 18 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: VTE
Interventions: VTE REHABILITATION: High-Caloric Expenditure Exercise Training (HCE) and The Dietary Behavioral Weight Loss Intervention (BWL); Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 16 Years to 79 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Weight Loss, Overweight and Obesity, Behavior, Health
Interventions: Active Intervention Group, Comparison Group; Behavioral
Lead sponsor: University of Tennessee; Other
Eligibility: 16 Years and older
Enrollment: 229 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Memphis, Tennessee

Search by objective public record fields.

Ignite Pilot: Goal Setting in a Digital Weight Loss Intervention

Medications After Adolescent Bariatric Surgery

Internet-Based Weight-Loss Program for Colorectal Cancer Survivors

Examining Cooking as a Health Behavior

Functional Assessment of Ashwagandaha Root Extract During Weight Loss

Functional Improvement in OSA and COPD With a Telehealth LifeStyle and Exercise Intervention

How Gas-Filled Intragastric Balloons or Endoscopic Sleeve Gastroplasty Affect Hunger, Hunger Hormones, and Gastric Emptying Compared to Meal Replacements

Comparison of Liraglutide Versus Placebo in Weight Loss Maintenance in Obese Subjects: SCALE - Maintenance

A Maintenance Program for the Be Fit Employee Wellness Program

Multicenter Endoscopic Sleeve Gastrectomy (ESG) Trial (MERIT Trial)

Weight Regain Treatment Post-Bariatric Surgery

Vida Sana y Completa Obesity and Food Insecurity Study

Food As Medicine for Heart Failure

A Phase IV Safety and Efficacy Study of VI-0521 in Adolescents With Obesity

Comparision of Aerobic Exercise to Aerobic Plus Yoga Exercise for Weight Loss in Adults With Overweight or Obesity.

Effect of Soy Protein and Colorado Diet on Weight Loss and Maintenance

A Phase 1 Study of VK2735 in Obese Adults Without Comorbidities

Inpatient Obesity Intervention With Phone Follow-up

Patient-Centered Weight Loss Program for Knee Replacement Patients

A Pilot Factorial Trial of an Integrated Lifestyle Intervention

Get Social: Randomized Trial of a Social Network Delivered Lifestyle Intervention

Evaluating the Feasibility of a Stepped-care Approach to Treating Adolescents With Binge and Loss of Control Eating

Exercise Training After an Acute Blood Clot

Choosing Healthy Activities and Lifestyle Management Through Portal Support