Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:08 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 145–168 of 272 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: 12-weeks of Weight Loss Clear all

Conditions: Breast Cancer, Overweight or Obesity
Interventions: Contrave, Behavioral Weight Loss; Drug · Behavioral
Lead sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; Other
Eligibility: 18 Years and older · Female only
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Obesity
Interventions: Saxenda®, Placebo; Drug · Other
Lead sponsor: Texas Tech University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 73 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 2
States / cities: Lubbock, Texas

Conditions: Human Immunodeficiency Virus, Metabolic Syndrome
Interventions: Intermittent fasting, Standard of Care; Behavioral · Other
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Food Addiction, Overweight and Obesity, Weight Loss
Interventions: Behavioral Weight Loss (BWL) counseling; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Diabetes Mellitus, Type 2
Interventions: LY2944876, Exenatide extended-release, Placebo, Metformin; Drug
Lead sponsor: OPKO Health, Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 420 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 31
States / cities: Concord, California • Fresno, California • Los Angeles, California + 27 more

Conditions: Postpartum Weight Retention, Overweight and Obesity
Interventions: Early Time-Restricted Eating (eTRE), Control; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Type 2 Diabetes Mellitus
Interventions: Intensive Lifestyle Intervention; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Diabetes Mellitus, Type 2, Obesity
Interventions: laparoscopic Roux-en-Y gastric bypass (RYGB) procedure, Lifestyle Intervention; Procedure · Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 25 Years to 65 Years
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 2
States / cities: Seattle, Washington

Conditions: Obesity
Interventions: Mayo Clinic Diet, Usual Care; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 64 Years
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Obesity, Overweight, Weight Loss, Health Behavior, Lifestyle Intervention
Interventions: Core Behavioral Weight Loss Intervention, Limit Red Zone Foods, Limit Eating Window, Increase Protein, Increase Fiber Intake; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 208 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Prediabetic State, Overweight and Obesity
Interventions: Diabetes Prevention Intervention, Enhanced Usual Care; Behavioral · Other
Lead sponsor: University of Texas at Austin; Other
Eligibility: 25 Years to 65 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Rio Grande City, Texas

Conditions: Hypertension, Vascular Diseases, Cardiovascular Diseases
Interventions: MINT-TLC, Control Condition; Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 60 Years and older
Enrollment: 251 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Obesity
Interventions: Internet-based weight loss program, Brief phone coaching, Extended phone coaching; Behavioral
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years to 70 Years
Enrollment: 452 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Obesity
Interventions: Standard Behavioral Weight Loss Program, Stepped-Care Weight Loss Program; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 25 Years to 55 Years
Enrollment: 363 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2011
U.S. locations: 2
States / cities: Chapel Hill, North Carolina • Pittsburgh, Pennsylvania

Conditions: Obesity
Interventions: MOMENTUM; Behavioral
Lead sponsor: University of Nebraska; Other
Eligibility: 19 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Lincoln, Nebraska

Conditions: Weight Loss
Interventions: Step 1 Treatment: APP, Step 1 Treatment: APP + Coaching, Step 2 Treatment Strategy: Modest Step-up, Step 2 Treatment Strategy: Vigorous Step-up; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 400 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Craniopharyngioma, Hypothalamic Obesity
Interventions: Syntocinon, Placebo (for Syntocinon); Drug
Lead sponsor: Shana McCormack, MD; Other
Eligibility: 10 Years to 35 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Obstructive Sleep Apnea, Obesity
Interventions: Laparoscopic Gastric Banding, Continuous Positive Airway Pressure; Procedure
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 65 Years
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Adult Survivors of Childhood Leukemia
Interventions: individual diet & physical activity counselor and website through Healthways at Hopkins, self directed weight loss, questionnaires, fasting blood draw, measurement of height, weight and waist circumference, and blood pressure; Behavioral · Other
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 358 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2025
U.S. locations: 2
States / cities: New York, New York • Memphis, Tennessee

Conditions: Obesity, Overweight, Metabolic Diseases
Interventions: Low Calorie Diet (LCD), Phentermine; Behavioral · Drug
Lead sponsor: AdventHealth Translational Research Institute; Other
Eligibility: 18 Years to 55 Years
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Obesity
Interventions: Daily Caloric Restriction (DCR), Intermittent Fasting (IMF); Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 60 Years
Enrollment: 165 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Weight Loss
Interventions: Standard Behavioral Weight Loss Intervention (SBWL), Campaign Intervention (CI); Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 55 Years
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Obesity, Dental Care for Children
Interventions: Dental Cleaning and Oral Hygiene Instruction (OHI), Oral Hygiene Instruction (OHI); Procedure · Behavioral
Lead sponsor: Oelisoa Andriankaja; Other
Eligibility: 12 Years to 17 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Appetite, Weight Loss
Interventions: Higher Protein (HP), Lower Protein (LP); Other
Lead sponsor: Purdue University; Other
Eligibility: 21 Years and older · Female only
Healthy volunteers: Accepts healthy volunteers
U.S. locations: 1
States / cities: West Lafayette, Indiana

Search by objective public record fields.

Adaptive Nutrition and Exercise Weight Loss (A-NEW) Study

To Predict Weight Loss Response to Liraglutide (Saxenda®), From fMRI-based Determination of Food Cue Reactivity

2-5 Intermittent Caloric Restriction in HIV

Behavioral Weight Loss Treatment for Individuals With Food Addiction

A Study to Compare a New Drug for Type 2 Diabetes to Placebo and to a Treatment Already Available for Type 2 Diabetes

Time-restricted Eating for Postpartum Weight Loss

Changing Lifestyles for Better Health

Calorie Reduction Or Surgery: Seeking Remission for Obesity And Diabetes

Weight Loss Through Mayo Clinic Diet

Reset: Enhancing Weight Loss in a Digital Intervention

Diabetes Prevention for Mexican Americans

Counseling Older Adults to Control Hypertension

Phone Coaching and Internet-delivered Weight Loss

Evaluating the Effectiveness of a Stepped-Care Approach to Long-Term Weight Loss (The Step-Up Study)

Maximizing Outcomes Needed After Percutaneous Coronary Intervention (PCI) Using Weight Management (MOMENTUM)

SMART Weight Loss Management

Intranasal Oxytocin in Hypothalamic Obesity

Apnea, Bariatric Surgery Versus Continuous Positive Airway Pressure (CPAP) Trial

Exercise and QUality Diet After Leukemia: The EQUAL Study

Effect of Caloric Restriction on Fat Oxidation in Obese Men and Women (Magellan II)

Intermittent Fasting Versus Daily Caloric Restriction for Weight Loss

Feasibility of a Campaign Intervention Compared to a Standard Behavioral Weight Loss Intervention in Overweight and Obese Adults

MODERN-Dental: Pediatric Obesity, Cardiometabolic Risks, And Periodontal Disease

Dietary Pork, Appetite and Weight Loss in Human