Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:16 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 169–192 of 272 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: 12-weeks of Weight Loss Clear all

Conditions: Weight Loss
Interventions: 2'-Fucosyllactose, Maltodextrin; Dietary Supplement
Lead sponsor: Advanced Protein Technologies Corporation; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: College Station, Texas

Conditions: Insulin Resistance, Obesity
Interventions: Roux-en-Y Gastric Bypass (RYGBP), Sleeve Gastrectomy (SG), Very Low Calorie Diet (VLCD); Procedure · Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Obesity, Exercise Reinforcement
Interventions: Exercise; Behavioral
Lead sponsor: University of Kentucky; Other
Eligibility: 18 Years to 40 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Type2 Diabetes
Interventions: Phone-Based Health Coaching Utilizing Lifestyle Action Plans; Behavioral
Lead sponsor: Beacon Health System; Other
Eligibility: 18 Years to 65 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: South Bend, Indiana

Conditions: Overweight, Obesity
Interventions: Counseling sessions, Wait List Control; Behavioral
Lead sponsor: University of Arizona; Other
Eligibility: 18 Years to 64 Years · Male only
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Type2 Diabetes, Coronary Artery Disease
Interventions: Liraglutide Pen Injector [Victoza], matching liraglutide-placebo pre-filled pens; Drug
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Obesity
Interventions: Standard, Early Intervention; Behavioral
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years to 70 Years
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Obstructive Sleep Apnea, Fat Disorder
Interventions: PAP Therapy, Lifestyle Counseling Intervention; Device · Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 70 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Obesity
Interventions: Core, Standard Diet Monitoring, Simplified Diet Monitoring, Adaptive Activity Goals (Daily), Adaptive Activity Goals (Weekly), Message Decision Points (Fixed), Message Decision Points (Adaptive), Message Decision Rules (Standard), Message Decision Rules (Adaptive), Message Choice (No), Message Choice (Yes); Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 39 Years
Enrollment: 759 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Cachexia-Anorexia Syndrome
Interventions: Selpercatinib, Strength Assessment; Drug · Other
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Overweight and Obesity
Interventions: ER, SBWC; Behavioral
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 13 Years to 17 Years
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Intellectual Disability, Overweight and Obesity
Interventions: Weight Loss Plus Cooking, Traditional Weight Loss; Behavioral
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years to 35 Years
Enrollment: 114 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: TRE plus SOC, SOC, TRE; Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2030
U.S. locations: 1
States / cities: New York, New York

Conditions: NAFLD
Interventions: NAFLD-specific weight loss intervention, Wait-list control; Behavioral · Other
Lead sponsor: University of Arizona; Other
Eligibility: 18 Years to 64 Years · Male only
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Breast Cancer, Weight Loss
Interventions: Weight Loss Counseling; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 75 Years · Female only
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Overweight and Obesity
Interventions: SMART 2.0; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 35 Years
Enrollment: 638 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Obesity
Interventions: Milk Thistle (MT), Lactobacillus Gasseri (LAC), Exercise (EX), Control (CON); Dietary Supplement · Behavioral
Lead sponsor: Kyle Flack; Other
Eligibility: 18 Years to 50 Years
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: PreDiabetes, Hyperglycemia, Glucose, High Blood, Overweight, Prediabetic State, Impaired Glucose Tolerance, Obesity, Weight Loss, Lifestyle, Healthy, Lifestyle Risk Reduction, Lifestyle, Sedentary
Interventions: Digital Diabetes Prevention Program (dDPP), Human Coach-based Diabetes Prevention Program (hDPP); Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 368 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 2
States / cities: Baltimore, Maryland • Reading, Pennsylvania

Conditions: Obesity, Weight Loss
Interventions: Standard Behavioral Weight Loss Treatment, AI-optimized Behavioral Weight Loss Treatment; Behavioral
Lead sponsor: Oregon Research Institute; Other
Eligibility: 18 Years to 70 Years
Enrollment: 301 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Obesity
Interventions: Roux-En-Y Gastric Bypass, Low-calorie Diet; Procedure · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 65 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Obesity
Interventions: Technology Supported, Standard; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 96 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm, Obesity-Related Malignant Neoplasm
Interventions: Behavioral Dietary Intervention, Educational Intervention, Health Promotion and Education, Internet-Based Intervention, Interview, Medical Device Usage and Evaluation, Mindfulness Relaxation, Physical Performance Testing, Questionnaire Administration; Behavioral · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: La Crosse, Wisconsin

Conditions: Obesity
Interventions: Roux-en-Y Gastric Bypass (RYGB), Sleeve Gastrectomy (SG), Very Low Calorie Diet (VLCD); Procedure · Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 51 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Pro-opiomelanocortin (POMC) Deficiency Obesity
Interventions: Setmelanotide, Placebo; Drug
Lead sponsor: Rhythm Pharmaceuticals, Inc.; Industry
Eligibility: 6 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Scottsdale, Arizona

Search by objective public record fields.

Effects of Human Milk Oligosaccharide Ingestion on Weight Loss and Markers of Health

Metabolism and Bariatric Surgery Study

Exercise and Weight Control

Pilot of Virtual Health Coaching Utilizing Lifestyle for Under-Resourced Patients With Type II Diabetes

Gender- and Culturally-Sensitive Weight Loss Intervention for Hispanic Males

Liraglutide Effects on Epicardial Fat Inflammatory Genes

Using a State-wide Initiative to Disseminate Effective Behavioral Weight Loss Strategies: Study 5

Metabolism and Sleep Apnea Treatment

Adaptive Goals and Interventions for Lifestyle Enhancement

Feasibility Study for Repurposing RET Inhibitors

Improving Emotion Regulation Skills Among Adolescents Attempting to Lose Weight

Cooking Skills to Improve Long-Term Weight Loss in Young Adults With Intellectual Disabilities

Diet and Meal Timing in Patients With Metabolic Dysfunction Associated Steatoic Liver Disease

A Gender and Culturally Specific Approach to Reduce NAFLD in Mexican-American Men

Lifestyle, Exercise and Nutrition Study 2 (LEAN 2)

SMART 2.0: Social Mobile Approaches to Reducing weighT in Young Adults

Exercise, Milk Thistle, and Lactobacillus to Influence Plasma Bilirubin

Effectiveness and Cost-Effectiveness of Fully-Automated Digital vs. Human Coach-Based Diabetes Prevention Programs

Using Artificial Intelligence to Optimize Delivery of Weight Loss Treatment

Bariatric Surgery Versus Diet Alone in the Bile Acid Pathway and Weight Loss

ENGAGED: E-Networks Guiding Adherence to Goals for Exercise and Diet

Virtual Mindfulness and Weight Management to Mitigate Risk of Relapse and Improve Wellbeing in Cancer Survivors

Cerebrospinal Fluid Biomarkers in Bariatric Surgery

Setmelanotide for the Treatment of Early-Onset Pro-Opiomelanocortin (POMC) Deficiency Obesity