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ClinicalTrials.gov public records Last synced Oct 1, 2026, 8:31 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–19 of 19 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: 2% Lidocaine HCl topical solution Clear all

Conditions: Acute Oral Mucositis Pain
Interventions: doxepin hydrochloride oral solution, DLA (diphenhydramine, lidocaine and antacids) rinse, Placebo; Drug · Other
Lead sponsor: Alliance for Clinical Trials in Oncology; Other
Eligibility: 18 Years and older
Enrollment: 275 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 350
States / cities: Anchorage, Alaska • Burbank, California • Dublin, California + 221 more

Conditions: Moderate or Severe Submental Fullness
Interventions: Deoxycholic Acid Injection, Placebo, Cold Compress, Lidocaine / Epinephrine, Loratadine, Ibuprofen, Compression Chin Strap; Drug · Other
Lead sponsor: Kythera Biopharmaceuticals; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Tempe, Arizona

Conditions: Lumbar Radiculopathy
Interventions: Corticosteroid injection; Drug
Lead sponsor: Lahey Clinic; Other
Eligibility: 30 Years to 75 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Burlington, Massachusetts

Conditions: Keratoconus
Interventions: Riboflavin-5-phosphate, Sham cross-linking; Drug
Lead sponsor: University at Buffalo; Other
Eligibility: 16 Years to 35 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2011
U.S. locations: 2
States / cities: Amherst, New York • Buffalo, New York

Conditions: Cystitis, Interstitial, Painful Bladder Syndrome
Interventions: Pelvic Floor Physical Therapy, Bladder Instillations; Procedure · Drug
Lead sponsor: Corewell Health East; Other
Eligibility: 18 Years to 85 Years · Female only
Enrollment: 128 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2027
U.S. locations: 1
States / cities: Royal Oak, Michigan

Conditions: Pain From onabotulinumtoxinA Injections
Interventions: onabotulinumtoxinA prophylaxis with Lidocaine, OnabotulinumtoxinA prophylaxis with Saline; Procedure
Lead sponsor: Association of Migraine Disorders; Other
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: East Providence, Rhode Island

Conditions: IUD Insertion Pain, IUD Insertion
Interventions: Benzocaine 20%, Lidocaine 2%, Sham injection, Saline 0.9%; Drug · Other
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older · Female only
Enrollment: 1 participant
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Healthy
Interventions: Videofluoroscopic swallow study, pharyngeal High Resolution Manometry; Procedure
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 45 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Postoperative Nausea and Vomiting
Interventions: 2% Lidocaine HCl topical solution, 0.9% Sodium chloride; Drug
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Pancreatitis
Interventions: Lidocaine Hydrochloride, Normal Saline; Drug
Lead sponsor: Abraham Mathew MD; Other
Eligibility: 18 Years and older
Enrollment: 506 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Diabetic Macular Edema (DME), Age-Related Macular Degeneration (AMD), Retinal Vein Occlusion, Diabetic Retinopathy (DR)
Interventions: Chloroprocaine Ophthalmic Gel 3% (IHEEZO), Sham Subconjunctival Injection, Proparacaine Hydrochloride Ophthalmic Solution 0.5%, Lidocaine Hydrochloride Injection 2%; Drug · Procedure
Lead sponsor: Harrow Inc; Industry
Eligibility: 18 Years and older
Enrollment: 236 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Tyler, Texas

Conditions: Bronchiectasis Adult, Mediastinal Lymphadenopathy, Pneumonia, Chest--Diseases, Infiltrates, Bronchopulmonary Disease, Cancer, Lung
Interventions: Topical lidocaine, Nebuliser solution, Nebuliser Suspension; Drug
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Macular Degeneration
Interventions: Proparacaine Ophthalmic, Tetracaine Ophthalmic, Lidocaine 4%, Lidocaine 2% Injectable Solution; Drug
Lead sponsor: Lahey Clinic; Other
Eligibility: 40 Years and older
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 3
States / cities: Arlington, Massachusetts • Burlington, Massachusetts • Peabody, Massachusetts

Conditions: Pain
Interventions: Microneedle Roller, Sham microneedle Roller; Device
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years to 60 Years · Male only
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Cervical Pain, Pelvic Pain
Interventions: Intracervical Lidocaine Injection, Topical Lidocaine Gel; Drug
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 74 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Chronic Migraine, Headache, Episodic Migraine
Interventions: Lidocaine 4% Topical Application Cream [LMX 4], Lidocaine Hydrochloride 2 mg/mL Injectable Solution, Normal Saline; Drug
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 7 Years to 21 Years
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Sleep Apnea Syndromes, Nasal Obstruction, Turbinate Hypertrophy
Interventions: Radiofrequency Turbinate Reduction, Sham RF; Procedure
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 80 Years
Enrollment: 242 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 3
States / cities: Seattle, Washington

Conditions: Peripheral Neuropathy
Interventions: Diode Laser fiber type Selective Stimulator, ZTlido 1.8 % Topical System, PeriCam PSI NR, Medoc Quantitative Sensory Testing, Inactive Topical System; Procedure · Drug · Diagnostic Test + 1 more
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Palo Alto, California • Salt Lake City, Utah

Conditions: Topical Anesthesia
Interventions: Lidocaine, Placebo, Propofol; Drug
Lead sponsor: Bassett Healthcare; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Cooperstown, New York

Search by objective public record fields.

Doxepin and a Topical Rinse in the Treatment of Acute Oral Mucositis Pain in Patients Receiving Radiotherapy With or Without Chemotherapy

Patient Experience Study of Deoxycholic Acid Injection

Preoperative Corticosteroid Epidural Injection and Lumbar Decompression Surgery Outcomes

Treatment of Keratoconus Using Collagen Cross-Linking

Bladder Directed vs. Pelvic Floor Therapy in IC/BPS

Topical Intranasal Anesthetic Block for Reducing the Pain of Botulinum Toxin Injections for Chronic Migraine

Intrauterine Device Insertion Pain Management

Swallowing Pressure Profiles in Healthy Adults

Intranasal Lidocaine for Prevention of Postoperative Nausea and Vomiting.

Topical Pancreatic Duct Lidocaine for Prevention of Post-ERCP Pancreatitis

Study Evaluating the Efficacy and Safety of Chloroprocaine HCl Ophthalmic Gel 3% vs Proparacaine Ophthalmic Solution 0.5% Plus Subconjunctival Lidocaine in Patients Undergoing Intravitreal Injections

Lidocaine Administration During Flexible Bronchoscopy and Endobronchial Ultrasound

Pilot Study: A Randomized Trial Of Anesthetic Agents For Intravitreal Injection

The Effect of Microneedle Pretreatment on Topical Anesthesia

Tenaculum Pain Control Study

Occipital Blocks for Acute Migraine

Randomized Clinical Trial of Nasal Turbinate Reduction to Improve Continuous Positive Airway Pressure (CPAP) Outcomes for Sleep Apnea

Diode Laser as a Biomarker for Neuropathic Pain of Peripheral Origin.

Impact of Topical Pharyngeal Anesthetics on Discharge of the Patients When Used in Conjunction With Propofol Sedation in Routine EGD's