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ClinicalTrials.gov public records Last synced Oct 6, 2026, 10:12 PM EDT

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Showing 25–48 of 62 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: 2% lidocaine gel Clear all
Completed Phase 3 Interventional

The Effect of Topical Lidocaine on Pain Scores During Manual Vacuum Aspiration for Nonviable Pregnancies

NCT01708330
View directory record Official record
Conditions
Nonviable Pregnancy
Interventions
Lidocaine, Placebo gel
Drug
Lead sponsor
Bridgeport Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 20, 2016 · Synced Oct 6, 2026, 10:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparative Ultrasound Analysis of Two Hyaluronic Acid Dermal Fillers

NCT05622851
View directory record Official record
Conditions
Volume Deficiency of the Midface
Interventions
Restylane Contour, Juvederm Voluma
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Santa Rosa Beach, Florida
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 6, 2026, 10:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

RHA Redensity - Perioral Rhytids

NCT03092219
View directory record Official record
Conditions
Perioral Rhytids, Aging, Wrinkle
Interventions
TEOSYAL RHA Redensity
Device
Lead sponsor
Teoxane SA
Industry
Eligibility
22 Years and older
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
6
States / cities
Beverly Hills, California • Santa Monica, California • Coral Gables, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 6, 2026, 10:12 PM EDT
Completed Phase 4 Interventional Results available

Lessons on Urethral Lidocaine in Urodynamics

NCT04038099
View directory record Official record
Conditions
Urethra Issue, Pelvic Organ Prolapse, Urinary Incontinence, Vaginal Vault Prolapse, Cystocele, Uterine Prolapse, Vaginal Prolapse, Pelvic Floor Disorders
Interventions
Water-Based Vaginal Lubricant, lidocaine topical
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Oct 6, 2026, 10:12 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Optimizing Pain Control in Transurethral Resection of the Prostate

NCT04102566
View directory record Official record
Conditions
Pain, BPH With Urinary Obstruction, BPH With Urinary Obstruction With Other Lower Urinary Tract Symptoms
Interventions
Ibuprofen 600 mg, Education
Drug · Behavioral
Lead sponsor
Benaroya Research Institute
Other
Eligibility
18 Years and older · Male only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 27, 2019 · Synced Oct 6, 2026, 10:12 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Efficacy of Lidocaine Gel Enema After Endoscopic Hemorrhoid Band Ligation for Relief of Post Procedural Pain

NCT03797703
View directory record Official record
Conditions
Hemorrhoids
Interventions
Lidocaine Hydrochloride 2% gel enema
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Oak Lawn, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 4, 2024 · Synced Oct 6, 2026, 10:12 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effectiveness of Synapse Transcutaneous Electronic Nerve Stimulation (TENS) During Dental Procedures Among Children

NCT03779659
View directory record Official record
Conditions
Dental Fear, Anesthesia, Local, Pediatric Dentistry
Interventions
Synapse TENS device, Topical anesthetic gel
Device · Drug
Lead sponsor
Boston University
Other
Eligibility
6 Years to 14 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 8, 2021 · Synced Oct 6, 2026, 10:12 PM EDT
Completed Phase 4 Interventional

Povidone Iodine vs AVEnova: A Pre-injection Disinfection Study (PAVE Study)

NCT04018482
View directory record Official record
Conditions
Age-related Macular Degeneration, Diabetic Retinopathy, Diabetic Macular Edema
Interventions
Povidone Iodine, Hypochlorous Acid
Other
Lead sponsor
California Retina Consultants
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Mar 10, 2020 · Synced Oct 6, 2026, 10:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Gene Expression Study Between Two Dermal Injectables Hydroxylapatite Semi-permanent Filler

NCT05620043
View directory record Official record
Conditions
Gene Expression
Interventions
Sculptra, Radiesse Plus
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years to 50 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 6, 2026, 10:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of Injected Local Anesthetic vs Topical Anesthetic in Cosmetic Injectable Fillers.

NCT02379221
View directory record Official record
Conditions
Anesthesia
Interventions
Injectable, Topical
Drug
Lead sponsor
David Grant U.S. Air Force Medical Center
Federal
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Travis Air Force Base, California
Source: ClinicalTrials.gov public record
Updated Apr 29, 2020 · Synced Oct 6, 2026, 10:12 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Pain Perception After Tubal Ligation

NCT01062087
View directory record Official record
Conditions
Pain
Interventions
Bupivacaine, Lidocaine
Drug
Lead sponsor
Oklahoma State University Center for Health Sciences
Other
Eligibility
21 Years to 52 Years · Female only
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 3, 2012 · Synced Oct 6, 2026, 10:12 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Self-administered Lidocaine Gel for Pain-control During Cervical Preparation for Dilation and Evacuation

NCT02852434
View directory record Official record
Conditions
Pain Management, Cervical Preparation
Interventions
Lidocaine Gel (2%), Lidocaine Paracervical Block (1%)
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 7, 2019 · Synced Oct 6, 2026, 10:12 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Tetracaine Versus Lidocaine Gel for Anesthetic Effect and Comfort in Patients Undergoing LASIK

NCT01383200
View directory record Official record
Conditions
Pain
Interventions
Tetracaine drop, Lidocaine gel
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 11, 2017 · Synced Oct 6, 2026, 10:12 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Double Blinded Randomized Trial Between Lidocaine And Plain Gel For Urethral Straight Catheterization And The Q-Tip Test

NCT00883103
View directory record Official record
Conditions
Pain
Interventions
2% Lidocaine jelly, Plain aqueous gel
Drug
Lead sponsor
Baystate Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 13, 2011 · Synced Oct 6, 2026, 10:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Trial of 2% Lidocaine Gel for Intrauterine Device (IUD) Insertion

NCT01292447
View directory record Official record
Conditions
Pain
Interventions
2% lidocaine gel, Placebo gel
Drug
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years to 49 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced Oct 6, 2026, 10:12 PM EDT
Terminated Phase 4 Interventional

Gelclair at Conditioning or After Oral Mucositis Diagnosed vs. Magic Mouth Wash in Stem Cell Transplant Recipients

NCT03490396
View directory record Official record
Conditions
Oral Mucositis
Interventions
Gelclair, First® Mouthwash BLM
Device · Combination Product
Lead sponsor
Midatech Pharma US Inc.
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 22, 2019 · Synced Oct 6, 2026, 10:12 PM EDT
Completed Not applicable Interventional Results available

Anesthesia Preference for Intravitreal Injection: Topical or Subconjunctival

NCT01640171
View directory record Official record
Conditions
Age-related Macular Degeneration, Central Retinal Vein Occlusion, Diabetic Macular Edema
Interventions
Xylocaine 2% Injectable Anesthetic, Proparacaine Hydrochloride 0.5% Drop, Tetravisc 0.5% Gel, Acuvail, Intra-vitreal Anti-VEGF Drug
Procedure · Drug
Lead sponsor
Retina Vitreous Associates of Florida
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Clearwater, Florida
Source: ClinicalTrials.gov public record
Updated Apr 21, 2014 · Synced Oct 6, 2026, 10:12 PM EDT
Completed Phase 4 Interventional

Lidocaine for Pain After Urodynamic Testing

NCT03390790
View directory record Official record
Conditions
Voiding Disorders, Overactive Bladder, Urinary Incontinence
Interventions
Lidocaine gel 2%, Standard lubricant gel
Drug · Other
Lead sponsor
Atlantic Health System
Other
Eligibility
40 Years to 80 Years · Female only
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 19, 2019 · Synced Oct 6, 2026, 10:12 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Tenaculum Pain Control Study

NCT01421641
View directory record Official record
Conditions
Cervical Pain, Pelvic Pain
Interventions
Intracervical Lidocaine Injection, Topical Lidocaine Gel
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older · Female only
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 21, 2014 · Synced Oct 6, 2026, 10:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

RHA® 4 With New Anesthetic - Nasolabial Folds

NCT04087395
View directory record Official record
Conditions
Aging, Pain
Interventions
RHA®4 with new anesthetic agent, RHA®4-Lidocaine
Device
Lead sponsor
Teoxane SA
Industry
Eligibility
22 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
3
States / cities
Beverly Hills, California • Coral Gables, Florida • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 24, 2022 · Synced Oct 6, 2026, 10:12 PM EDT
Not listed Phase 2Phase 3 Interventional Accepts healthy volunteers

Treatment of Keratoconus Using Collagen Cross-Linking

NCT00841386
View directory record Official record
Conditions
Keratoconus
Interventions
Riboflavin-5-phosphate, Sham cross-linking
Drug
Lead sponsor
University at Buffalo
Other
Eligibility
16 Years to 35 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
2
States / cities
Amherst, New York • Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 11, 2009 · Synced Oct 6, 2026, 10:12 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Lidocaine for Pessary Check Pain Reduction

NCT05493735
View directory record Official record
Conditions
Pelvic Organ Prolapse, Stress Urinary Incontinence
Interventions
Lidocaine Hcl 2% Jelly, Placebo Jelly
Drug
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Dec 14, 2023 · Synced Oct 6, 2026, 10:12 PM EDT
Withdrawn Phase 2 Interventional

RCT of SPG Blocks for Post-dural Headache

NCT03560349
View directory record Official record
Conditions
Post-Dural Puncture Headache
Interventions
Lidocaine HCl Gel 2%, placebo gel
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 50 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 13, 2022 · Synced Oct 6, 2026, 10:12 PM EDT
Completed Phase 3 Interventional Results available

A Study to Compare the Safety and Effectiveness of a Non-FDA Approved Device Dermal Gel Extra (DGE) and an FDA Approved Device for the Correction of Nasolabial Folds (NLFs)

NCT00444626
View directory record Official record
Conditions
Facial Wrinkles at the Nasolabial Folds
Interventions
Dermal Gel Extra (DGE), Restylane, EMLA Cream
Device · Drug
Lead sponsor
Genzyme, a Sanofi Company
Industry
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
6
States / cities
Birmingham, Alabama • La Jolla, California • Miami Beach, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2015 · Synced Oct 6, 2026, 10:12 PM EDT