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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: 2 Mediterranean Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Complex Effects of Dietary Manipulation on Metabolic Function, Inflammation and Health

NCT02706262
View directory record Official record
Conditions
Obesity, Insulin Resistance
Interventions
Metabolically abnormal obese - Mediterranean diet, Metabolically abnormal obese - Low carbohydrate ketogenic diet, Metabolically abnormal obese - Plant-based, very-low-fat diet, Annual Follow-up Visits
Other · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 55 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Sep 22, 2026, 10:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Fasting Mimicking Diet

NCT04150159
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
FMD Arm
Dietary Supplement
Lead sponsor
Hypertension Institute, Nashville
Other
Eligibility
35 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 30, 2020 · Synced Sep 22, 2026, 10:04 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Ketone Conferred Resiliency Against Sleep Restriction With Nutritional Intervention.

NCT06075914
View directory record Official record
Conditions
Sleep Deprivation, Nutritional Intervention
Interventions
Ketogenic Intervention, Mediterranean Intervention, Placebo, Ketone Ester
Other · Dietary Supplement
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 22, 2026, 10:04 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

The Healthy Diet and Lifestyle Study II

NCT05132686
View directory record Official record
Conditions
Intra-Abdominal Fat
Interventions
IER+MED, MED/DER
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
35 Years to 69 Years
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Sep 22, 2026, 10:04 PM EDT
Completed Phase 2 Interventional Results available

Rilonacept for Treatment of Familial Mediterranean Fever (FMF)

NCT00582907
View directory record Official record
Conditions
Familial Mediterranean Fever
Interventions
Rilonacept, Placebo
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
4 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
5
States / cities
Los Angeles, California • Madera, California • Bethesda, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2013 · Synced Sep 22, 2026, 10:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healthy Eating for Colon Cancer Prevention

NCT00475722
View directory record Official record
Conditions
Colon Cancer
Interventions
1 Healthy Eating, 2 Mediterranean
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
21 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 25, 2016 · Synced Sep 22, 2026, 10:04 PM EDT
Completed Not applicable Interventional Results available

Trial of Specific Carbohydrate and Mediterranean Diets to Induce Remission of Crohn's Disease

NCT03058679
View directory record Official record
Conditions
Crohn Disease
Interventions
Diet
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
197 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
35
States / cities
Tucson, Arizona • San Francisco, California • Denver, Colorado + 27 more
Source: ClinicalTrials.gov public record
Updated Jul 20, 2021 · Synced Sep 22, 2026, 10:04 PM EDT
Active, not recruiting Not applicable Interventional

Circadian Health Regulation and Optimization for Rejuvenation Outcomes

NCT07203196
View directory record Official record
Conditions
Aging, Healthy, Blood Sugar; High, Blood Sugar (Glucose) Control, Time Restricted Eating, Circadian Dysregulation
Interventions
Circadian Rhythm Optimization
Behavioral
Lead sponsor
Salk Institute for Biological Studies
Other
Eligibility
50 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Sep 22, 2026, 10:04 PM EDT
Completed Not applicable Interventional

Dietary Intervention and Gastrointestinal Function in Patients With Parkinson's Disease

NCT03851861
View directory record Official record
Conditions
Parkinson Disease
Interventions
Mediterranean Diet
Other
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 85 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 3, 2021 · Synced Sep 22, 2026, 10:04 PM EDT
Completed Phase 4 Interventional Results available

Real World Effectiveness of Combining an Employer-based Weight Management Program With Medication for Chronic Weight Management in Employees With Obesity

NCT03799198
View directory record Official record
Conditions
Obesity
Interventions
Weight Management Program (WMP), Medication for chronic weight management (Rx)
Other · Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 13, 2022 · Synced Sep 22, 2026, 10:04 PM EDT
Recruiting Not applicable Interventional

Mobile Health Dietary Intervention for Stroke Survivors With Prediabetes or Type 2 Diabetes

NCT07120334
View directory record Official record
Conditions
Stroke Recurrence, Type 2 Diabetes, Prediabetes
Interventions
PortionSize Ed + MedDiet Support, Standard of care for Stroke and Prediabetes or T2D
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
30 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 22, 2026, 10:04 PM EDT
Recruiting Not applicable Interventional

Mediterranean Diet vs no Dietary Intervention for Improving Signs and Symptoms of Psoriasis in Patients Treated With Anti-IL-17 or Anti-IL-23 Inhibitors

NCT06399432
View directory record Official record
Conditions
Psoriasis
Interventions
Mediterranean Diet
Behavioral
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 94 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 22, 2026, 10:04 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pharmacokinetics Study of Colchicine in Familial Mediterranean Fever (FMF) Patients

NCT01075906
View directory record Official record
Conditions
Familial Mediterranean Fever
Interventions
colchicine sprinkle capsules
Drug
Lead sponsor
Mutual Pharmaceutical Company, Inc.
Industry
Eligibility
2 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 9, 2012 · Synced Sep 22, 2026, 10:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mediterranean Style Diet and Low Glycemic Responses

NCT03410719
View directory record Official record
Conditions
Insulin Sensitivity
Interventions
Hi GI
Other
Lead sponsor
Purdue University
Other
Eligibility
30 Years to 69 Years
Enrollment
166 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 16, 2020 · Synced Sep 22, 2026, 10:04 PM EDT
Withdrawn Not applicable Interventional

Mycobiome Supporting Diet to Reduce GI Toxicity Associated With ASCT

NCT04685525
View directory record Official record
Conditions
Autologous Transplant, Myeloma
Interventions
Mycobiome Supporting Diet
Behavioral
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 25, 2024 · Synced Sep 22, 2026, 10:04 PM EDT
Completed Not applicable Interventional Results available

Stroke Telemedicine Outpatient Prevention Program for Blood Pressure Reduction

NCT03923790
View directory record Official record
Conditions
Stroke Prevention, Blood Pressure, Telemedicine, Psychosocial Impairment
Interventions
Educational Packet, Phone call at 72 hours by discharge nurse navigator, Telehealth visit at 7 days, 1 month, 3 months, and 5 months after discharge, Educational messages every other week, BP monitoring by QardioARM with periodic transmission of BP data
Behavioral · Diagnostic Test
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 8, 2022 · Synced Sep 22, 2026, 10:04 PM EDT
Completed Not applicable Interventional Results available

Personalized Dietary Management in Type 2 Diabetes

NCT05046886
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Standardized, Usual Care Control (UCC), Personalized Guidance to Minimize Postprandial Glycemic Response (PPGR)
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years to 80 Years
Enrollment
294 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 22, 2026, 10:04 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Impact of Dietary Intervention on Inflammation and Microbiome Composition Post-Colonoscopy

NCT06603519
View directory record Official record
Conditions
Colorectal Polyp, Inflammation, Dietary Intervention, Microbiota, Colorectal Neoplasms, Metabolomics
Interventions
Modified Plant-Based Mediterranean Diet
Dietary Supplement
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 22, 2026, 10:04 PM EDT
Completed Phase 3 Interventional

The Heart Institute of Spokane Diet Study

NCT00269425
View directory record Official record
Conditions
Myocardial Infarction
Interventions
American Heart Association Step 2 diet, Mediterranean diet
Behavioral
Lead sponsor
Providence Health & Services
Other
Eligibility
18 Years and older
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2008
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Aug 23, 2010 · Synced Sep 22, 2026, 10:04 PM EDT
Not listed Not applicable Interventional

Lifestyle Intervention to Reduce Body Weight and Systemic Inflammation Among World Trade Center Responders

NCT05138198
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Overweight and Obesity, Metabolic Syndrome, Inflammation
Interventions
Mediterranean Diet & Physical Activity, Usual Care
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
40 Years to 65 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Commack, New York
Source: ClinicalTrials.gov public record
Updated Nov 29, 2021 · Synced Sep 22, 2026, 10:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mediterranean Diet and the Gut Microbiome

NCT03269032
View directory record Official record
Conditions
Irritable Bowel Syndrome
Interventions
American Diet, Mediterranean-style Diet
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Sep 22, 2026, 10:04 PM EDT
Recruiting Not applicable Interventional

FAST-M: Prolonged Overnight Fasting and Mediterranean Dietary Intervention for Patients With Multiple Myeloma or Its Precursor Disease

NCT07446777
View directory record Official record
Conditions
Multiple Myeloma, Monoclonal Gammopathy of Undetermined Significance, Smoldering Multiple Myeloma
Interventions
Health Coaching, Prolonged Overnight Fasting (POF), Mediterranean Diet, Supportive Materials
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 22, 2026, 10:04 PM EDT
Completed Not applicable Interventional

Immune Modulation by Enhanced vs Standard Prehabilitation Program Before Major Surgery

NCT04498208
View directory record Official record
Conditions
Surgery, Immune System and Related Disorders, Preoperative Care, Gastrointestinal Disease, Urological Disease, Gynecologic Disease, Thoracic Diseases
Interventions
Physical Prehabilitation, Stress Reduction Prehabilitation, Cognitive Prehabilitation, Nutrition Prehabilitation
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced Sep 22, 2026, 10:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Remote Weight Management Program for Obese Women

NCT05635097
View directory record Official record
Conditions
Weight Loss
Interventions
Motivational Interviewing counseling on the Mediterranean diet and weight checks at regular intervals
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 1, 2023 · Synced Sep 22, 2026, 10:04 PM EDT